Best (in no particular order):
Ash (Manchester Apollo, Decemeber 1999). My first ever gig. Was absolutely mesmerized.
The Charlatans (Delamere Forest, 2009ish)
The Charlatans (MEN Arena, 2008?)
Madness 2009 (GMEX, refuse to call it Manchester Central or the MEN the AO Arena lol)
Future Islands (Manchester Cathedral 2014/5)
Foo Fighters, The Strokes, Angels and Airwaves (loved them but not so good live and got various stuff flung at them!), The Subways and Eahles of Death Metal. Thought I remembered the Manic Street Preachers being there but that may have been another gig? (Lancashire County Cricket Club 18th June 2006)
Muse MEN Arena (2005 or 2006 or something haha)
Heavens (Manchester Club Academy 2007 or something, memory ia terrible)
Alkaline Trio (Liverpool Echo Arena I think, 2007ish)
Funeral for a Friend (Manchester Apollo 2007ish)
There are so many, many more.
Worst:
So wanted to love Placebo (GMEX 2008/9) but they were better on CD! Their 2006 gig at the MEN was sooo much better.
The Cure (Leeds 2022) was slightly disappointing. Have liked them since being young but I think they played too many new songs! They can't play all the old uns though I suppose.
There will be loads more but posting before it gets lost.