Mounjaro July 2024 - continued

[Lumirubin]

The first thread was almost full, so I thought I'd start a second so we can carry on the fab support!
I don't think I could manage tagging everyone!! But here is the link to the first thread https://www.mumsnet.com/talk/weight-loss-injections/5101435-mounjaro-july-2024?page=1

I've had 4 doses of 5mg and I've got a 7.5 really, I think I'll take the 'bonus' dose but the last 5mg I had didn't really give me any suppression. It was brilliant for the first 2, maybe 3, but now I'm constantly hungry and wanting to eat

It's my weigh-in day today, it's been 8 weeks on Mounjaro - seems to have flown by.

SW: 139kg (21st 12lbs)
CW: 122.8kg (19st 4lbs)
GW: 112kg (17st 9lbs)

That's a total of 16.2 kg down, or about 36lbs. A NSV for me is a really little thing but it pleases me - I was having to do my watch strap up on the last hole 8 weeks ago, and now it's gone in by two holes and it's not tight at all.

I'm finding that I have almost no knee pain at the moment, and feel a lot lighter just going about my daily life. I went bowling recently and I can't easily lift a 15lb bowling ball with one hand, yet I was carrying the equivalent of 2.5 of them around when at my heaviest weight. Crazy. Still have a long way to go though, my current goal weight is an interim goal of another 10% of my body weight. I can't bear to write my actual final goal down as it's so far away!

@SilenceInside i reckon go for the 7.5 mg pen but count clicks for 5 mg doses…better value for money then, as long as your comfortable with going beyond the 30 day limit.

@KeepinOn well done, the clothes fitting better is really motivating!

I have my bonus dose of the 5mg pen to take at the weekend. Then I will move up to the 7.5mg pen but count the clicks to do 6mg for a couple of weeks before doing 7.5mg.

I have been 11st 9.5 since Sunday. The scales have not budged. However, I gave blood yesterday and today I am 11st 8! Apparently you burn 650 calories giving blood as 'according to researchers at the University of California, San Diego. This happens because the body uses energy to replace the red blood cells that are removed.'

I took my bonus dose from my 5mg pen yesterday, and injected the whole lot - 0.75ml. Not sure what exact dose that is, but man, I'm feeling it today. Absolutely shattered and no desire to eat anything at all. And the worst part is, I'm really not sure why I did it, as my next pen is also 5mg 😂

0.6ml is the normal quantity so would be 5mg for your 5mg pen. 0.75 is 0.6 multiplied by 1.25. So you also multiply the 5mg by 1.25 which makes your dose 6.25mg.

Thanks @SilenceInside - really kind of you to work it out, I haven't had the mental capacity to even want to try today!

Ooops Mounjaromunchie, hope you feel better soon! I think that must be why prescribers caution against using the 'bonus' dose and counting clicks etc, people don't know how much they're taking.

I had a bad experience too on the bonus dose of my 2.5mg pen and have been stuck on 3.75mg ever since 🫣😂

@NewLifter @SilenceInside It may not actually be the MJ that had me feeling crook yesterday, I've woken up absolutely full of cold today. Also gutted to have gained a pound this week, but I've already given myself a stern talking to about water weight - I've 100% been in a deficit every day since starting MJ. Could also be muscle gain from the gym, but my understanding is that that's nigh on impossible when eating in a deficit.

Just completed Week 9 (it has been years since I managed to stick to a diet for this long). Despite, what I thought would be a difficult week (family events and revising for an exam), I have managed to continue to lose weight. Last Saturday I only used half the bonus dose (as my pen broke mid injection) so I injected myself on Wednesday and that worked well. My appetite suppression is still reasonably good on 5.0mg and my side effects are virtually zero.

Week 1 loss 1.6kg
Week 2 loss 1.1kg
Week 3 loss 1.2kg
Week 4 loss 1.4kg
Total loss on 2.5mg = 5.3kg

Week 5 loss 0.8kg
Week 6 loss 0.9kg
Week 7 loss 0.6kg
Week 8 loss 0.7kg
Week 9 loss 0.9kg
Total loss on 5.0mg = 3.9kg

Total weight loss = 9.2kg (or just over 20lbs)

So just 0.8kg to my first mini goal of losing 10kg.

I have fully moved down a size in my clothes. Bought some tops on vintage a size down from that (but they feel snug - I like clothes to feel reasonably lose and shapeless…wonder if that will change).

diian - Well done for giving blood and thanks for the information about the calorie loss!

SilenceInside - Amazing weight loss, well done.

MounjaroMunchie - Hope you feel better soon.

I've come to the end of week 8 and my second 2.5mg pen - and this week, weirdly, I have had a major whoosh. I had expected the 2.5mg to lose its power but actually I have lost really well in the second month on it, with no side effects and I've really been enjoying food though obviously in moderate amounts.

So I am now extremely anxious about the 5mg pen in my fridge waiting for me tomorrow! I desperately do not want nausea or vomiting or diarrhoea or sulphur burps, and with the 2.5mg being so very effective I'm wondering if I should count clicks and take half doses of the new pen. I just hate the idea of messing about with it - I've never taken a bonus dose as I am an inveterate rule follower and I feel because I have a 5mg pen I should take it as it's supposed to be taken.

So I'm undecided!

@WeepingInASunlitRoom I am an inveterate rule follower too, but I have just taken a 5mg dose from my current 7.5mg pen. So counted 40 clicks instead of continuing on to the full 60. It didn't feel like a massive "rule break", and it was straightforward to do. Everything else apart from the counting of the clicks was the same process as all the other times.

I have had some digestive issues on the 5mg although it's settled now, but I was just very concerned about the 7.5mg being too much. I've got lots of suppression on the 5mg and so I realised I wanted to continue on with that. I ordered the pen a while ago and at that time was worried that I might need to move up if the 5mg had stopped being so effective. Hence getting the 7.5 🤦🏼‍♀️

That's interesting @SilenceInside thank you! My whoosh reversed itself back to my standard 2lb a week loss which is fine, that's a perfectly acceptable rate to lose at - I think I have found peace with that now I have the confidence that I will keep losing weight on this medication so if it's slower than others or if there are a couple of blips and plateaus along the way I feel secure that overall it is working and will continue to work.

So I might try a 5mg dose, given that it's the therapeutic dose and I'd like to see if it does speed things up and how that feels, but if the side effects are bad then I'll count clicks for a lower dose going forwards. Work is busy in September, I work from home so can manage symptoms more easily but I need my wits about me!

@WeepingInASunlitRoom i didn’t tolerate the bonus dose in the 2.5mg pen very well so I’ve stuck at 3mg doing 38clicks of the 5mg pen. It’s worked well for me I’m consistently losing and have lots energy with no side effects impacting my life.

Weigh in number 9 and happy to report a loss of 3lbs this week, pleased with that after no loss last week, I'm now into the 12's and 27 lbs down. Had my last dose from my 5mg pen, it was a little more than 5 and I'm feeling a bit nauseous this afternoon...hoping suppression kicks in as the 5mg was wearing off. Got my 7.5 ready to go next week.

Well done on all the other losses and NSVs this week 👏

Thank you. I just took a 5mg dose and I now feel extremely nervous. I am a bit phobic about vomiting so really afraid that I will and that there is nothing I can do until the drug reduces in my system if that happens. However, I never got any gastric symptoms with 2.5mg so hopefully this is just anxiety talking. And if it doesn't go well, I will follow your example, thank you.

Well done everyone! Some great losses. I can totally relate to this being the longest I’ve stuck to a “diet”. Normally by now I’m starting to let the bad habits creep back in but with this I feel like I’m still just getting started.

I’ve been steady loosing 2lbs the last few weeks. I’ve lost 2st 11lb now which I’m thrilled with! That 3 stone and my next stone bracket are both in sight. I weigh what I did pre pregnancy now which feels good albeit 3 years later! Oops.

I had a weird one last week. I took the bonus dose from my 5mg pen and had the same suppression/symptoms as I’d had on the 5mg. Then my first dose from the 7.5 pen it was like I had come off the drug completely. My suppression was gone after 2 days, zero symptoms even after eating a take away which would have crippled me usually. I got my usual injection site reaction though so I’m 99% certain it wasn’t a misfire or anything. Took my 2nd 7.5mg on Sunday and I can tell I’m on it again, massive suppression, nausea and fatigue but thankfully the digestive symptoms have stayed at bay. We’ve had covid doing the rounds In my wider family and I’ve felt a bit ropey last week so wondering if being poorly has affected the efficacy of the drug maybe. Who knows!

Well I spoke too soon about the digestive symptoms staying at bay!! It’s about to be an uncomfortable hours drive to work for me!! I hope I have a really decent loss this week as a result because man this is awful!

Yikes! I started taking psyllium husk at the weekend due to constipation, seemed to kick in yesterday. Was a scary drive home! Hope you made it

Joining in with the digestive symptoms here, 48 hours after the 5mg jab and violent, painful diarrhea kicked in and went on all through the night.

Part of me this morning is furious with myself and framing this as I ordered drugs off the Internet (ok, Asda online pharmacy), injected them into my body and now I'm ill and in pain, can't eat, can't go to the gym, will struggle to work today - how can this be a positive health decision?

I'll certainly be going straight back down to 2.5mg and staying there - I am not capable of staying on a higher dose if this is the price.

Hope everyone else is doing better!

I've been described as having the constitution of an ox, and have only had mild nausea and mild constipation as side effects from the 2.5 and then moving up to the 5. But I also feel like I'm pushing my luck a bit and don't want to risk anything terrible by moving up to 7.5 if I'm happy with results at 5 - which I am.

Am I the only one making comparison pics from how I looked earlier this year to now? I'm using google photos to create side-by-side collages and the differences are shocking! So different.

Also, my partner and I suddenly noticed I've stopped snoring! Another win.

@WeepingInASunlitRoom sorry it’s kicked in for you ☹️ I had similar after my first 5mg. After 5 weeks of 2.5mg, I did 2 x 3.75mg then a 5mg and had v bad burps and diarrhea (and didn’t even lose weight that week!). Went back to 3.75mg for one then did another 5mg last night so a bit nervous myself.
the burps are back with a vengeance but peppermint oil capsules are amazing. Am waiting to see if diarrhoea hits tomorrow but I feel like it will 🙄

The burps are awful @User364837 - I don't think I could risk this again. I hope it holds off for you!

I'm vomiting now. I don't think I'll be able to take any more injections now this has happened - really wish I'd stuck to 2.5 all along! But now I will worry about this happening again even if I drop back down - I don't know how long this 5mg dose will be in my system for. It's really unbearable.

Oh @WeepingInASunlitRoom so sorry to read this. How are you doing today?