The oblivious condescension.
The main way this manifests is seeing the common and everyday aspects of sex as just too boring, and obsessively focusing on the 'inner truth'. Even when totally irrelevant, as per 'trans'.
As an analogy, it's like someone who thinks of themselves as a profound physicist because they know of special relativity, and that Newton's laws of motion are only approximations.
Of course, lots of other people know this, but don't bring it up when considering everyday issues because it's irrelevant. And unsurprisingly get exasperated when the wannabe 'profound thinker' keeps interjecting with 'but if your relative velocity approaches the speed of light'.
But for the 'profound thinker', they can only ever discuss the errors in Newton's laws. Or facts about males and females. To discuss the far larger accuracies would be beneath them.
Someone discussing 99.99999% of the truth and ignoring 0.00001% shows themselves to be ignorant.
Continually interjecting about 0.00001% of the truth and ignoring 99.99999% of it shows you to be profound and smart.
A childishly stupid way to approach things. Narcissistic, even. With negative practical value to society.