Shelagh will give birth to a live and healthy baby. I'm going to call it now (I have limited insider knowledge this year - which adds to my suspicions). It will be bumpy but will be successful. That's my prediction! 
And I don't predict any health problems for Shelagh in this series. Can't speak for the next 3!
I predict Sister Ursula to be done by ep 4! Shame!
This is just my predictions, based on very little other than a knowledge of how the writers think. Just call me Mystic Meg. God I'm annoying...