I'm also going to go against the grain, I'm 51 and had never tried profilo before despite using Botox and fillers.
I had my second session about 2 months ago and it's given me the most glowy skin I've ever had. I've put a before and after photo. The lighting is slightly different but if you zoom in my under eye wrinkles have improved dramatically where it has spread as well as my whole face looking plumper.
@JustFrustrated I recently bought a lip duo from by Terry, it's got a scrub and the rose lip balm in and it's really lovely as well as being extremely hydrating it was on offer too!
@jibbe I too have been using the perricone cold cream on my neck and décolleté and it's fantastic. Skin looks smoother and seems plumper, not cheap but worth it.
@DuncanBiscuits try the revitalash for eyebrows. Mine used to be quite thin but are much thicker now ( although still get the odd white hair 
). Laminating is a good shout as well, it makes a huge difference in conjunction with threading to tidy them up.
I agree entirely with using a medical professional. My practitioner is a qualified Dr and I really trust him. I've been using him for 4 years now and he's absolutely brilliant .
As a topical treatment I've recently discovered, which I use in conjunction with the Md perricone cold plasma cream - Bioeffect EGF serum and it's been a complete game changer for me. My skin is pretty ok for 51 anyway due to the profilo but I tried this and the results are gorgeous. I wouldn't be without it now.