Sorry cyteen, not anxious at all. DH is away weekly with work and it's not often that I go away for either the day or overnight but it does happen. We were super worried about DD1 when we left her for the first time together at 18 months, especially as her grandparents (who we leave them with) aren't local and super familiar. She went to nursery as usual though and they kept her busy and utterly spoilt the rest of the time. She didn't notice a bit apparently.
Our second attempt at going away pre-DD2's birth, some of those with good memories around here might remember was a disaster as she woke up being sick on the day we left. She seemed a bit better so we left as planned but she then got worse and worse. In the end my Mum called us to come home. Naturally the 24 hr bug was up just as we walked back through the door. (Definitely a bug though and not anxiousness)
We really are far more worried about my Mum than the girls - they have each other too. We plan to keep much of their normal routine going and are going away on the days they'd normally be at nursery anyway. My Mum's also coming to stay in August, mainly to help out then but it'll also be good practice for both her and the girls.
Honestly, DS will be fine. They're old enough too now to explain that you will go away but you will come back. We actually told DD1 on that first occasion that we were both going away to work as she was used to us both doing that and we always came home.
Really must go to bed now. Poor DH needs to be at the airport by 5.30am tomorrow so needs to sleep now. Night all!