Mostly. We didn't when we were young - as children my sister and I would quarrel and even physically fight quite a lot, and then as teenagers we despised each other as we had basically opposite tastes in everything.
But once we got to adulthood, we gradually developed a closer relationship - I'm sure others are the same - that uniquely shared history where you instantly know what the other is talking about does a lot to cover other differences.
I have to give her space, though. She has a kind of limited tolerance of people generally and has sometimes lashed out at me if I've breached it; I don't tend to do that in return. If I let it alone, she'll get over it.
We do have very different tastes and style. She's a jeans/t-shirt/zero make up sort of person, whereas I'm a skirts and dresses routinely wear make-up person. Musically, I joke that there's only one song in the entire history of rock and pop that we both like. However, we share the same favourite colour and have a bit of friendly rivalry as to which of us has got in first wearing it when we go out together. We do look very alike facially and have very similar hair though hers is always in better nick than mine.
Ultimately, we love each other and though we are not a gushy, touchy-feely family, we are not afraid to say 'I love you' when the occasion is right.