Not any that I haven’t got over, but the one that shook me and really stayed with me for a good couple of months was Adan Canto. I had just discovered “The Cleaning Lady” and was surprised they killed off a prominent character towards the end of the second season. I was googling why they left the show and was shocked to find articles about Adan (the main male lead) dying. He hadn’t even told the rest of the cast and crew about his cancer because it was one that it was something like 1 in a million die from. So the show runners and he obviously thought he just needed a few months off - so they wrote a storyline around that. And then he died! So, so sad as he was so young too.
I was incredibly sad about Matthew Perry, but not shocked.