Anyone not lost weight on wegovy pill after 2 months?

[BountyChoc]

I've been following the wegovy pill threads here and am seeing lots of people post about their weight loss.

I started 2 months ago, did the 1st month at 1.5mg, went up to 4mg in the second month.

I've lost zero pounds over the 2 months, so am going to try 9mg but I'm assuming this just might not work for me.

Take it first thing in the morning with a sip of bottled plain water, don't eat or drink anything after for at least 30 mins.

Maybe it just doesn't work for me? I'm thinking if I continue to have 0 weight loss next month on 9mg to give up.

I could easily eat a massive meal I've not noticed any effects of feeling too full up to eat.

I've also had two bouts of 24hs of vomitting and diarrhoea 30 days apart. I thought I got norovirus the first time but since it happened again a month later it is making me wonder whether the wegovy pill might be reacting with something I've eaten?

Just a bit lost atm and don't know whether to give up on it.

I'm 5'3" and 14 stone. I was 14 stone when I started at the beginning of aug and I'm still 14 stone. I guess that's a good thing that I haven't gained?

its making poor choices and overeating that made me fat to begin with. If it were as simple as reducing calories and eating more salad, id not need to spend £100s on these pills

who knows what the long term benefits of the pills will be, as they have only been available since July so unlikely to be many people on the higher doses

maybe the pills are not as effective as the jabs

I never really get this argument. Obviously you need to eat less to lose weight but the entire point of the pill is to make you want to eat less, or unable to eat more, whatever it might be. If it has no effect on appetite then it’s pointless really, I can force myself to eat less with no pill but it’s hard work and I’ll be hangry, why would I pay for the pill if it’s still going to be the same hard work? People are able to make changes to their diet precisely because of the effects of the pill/jab when it’s working, not because they’ve suddenly decided to make an effort, otherwise they wouldn’t need the pill/jabs in the first place.

What’s the point of them then? I couldn’t count calories and make better choices, that’s why I opted for the medication

Good to know 👍

There was an article the other day saying it's not effective for some people. I'm seeing some weight loss (which seems to have stalled) but nothing drastic. My intake is a lot less.
Have you tried leaving longer before eating or drinking? Research shows that 1.5 hours is the optimum. I try to do this, do if I wake some time between 5 & 6 I take it then.

i was hoping to lose a stone and feel more energised and motivated . I used to run a lot but being overweight doesn’t help with joint strain

🙄

Sp the advice in the leaflet is to wait half an hour

the people on MN said to wait an hour

now you’re saying 1.5 hours

it all very frustrating

@bananaobama the Wegovy tablets are a bit less effective than the Wegovy injections, and both are less effective than Mounjaro.

The effects of the tablets take a while to build up, as the medication builds in your system. The first dose level is to get your system used to the medication and isn't expected to produce significant weight loss, although for some people it may.

Remember, on the Wegovy tablet clinical trial research, on average people lost about 14% (or around 33lbs) of their bodyweight over 64 weeks. That's an average of 0.5lbs a week, and they would have been on the 25mg dose.

Anyone else finding that eating relieves the nausea?

That’s good to know. Thanks

i think that sounds like a sensible and reasonable rate to lose weight

@BountyChoc

we need to keep going

The instruction in the leaflet is to wait "at least 30 minutes". The suggestion to try waiting an hour or 1.5 hours is just in case for some reason your system takes a bit longer than other people's to digest and absorb the medication. It's not an instruction, it's a suggestion to try to see if makes a difference. It still fits with the leaflet instruction to wait at least 30 minutes.

@BountyChoc You’ve probably seen this phrase before if you’ve been reading in the group: GLP1s are useful tools, they are not the full solution.

From what you’ve described, it sounds like you may be expecting the GLP1 to do most of the heavy lifting. Unfortunately, for many people, it doesn’t quite work that way. The effects can be much more subtle. That doesn’t mean it isn’t working or that all is lost,you may still be able to get benefit by working with the medication rather than expecting it to do everything for you.

Based only on my own experience, my advice at this point would be:

1. Calculate your sedentary TDEE and work out your calorie deficit
2. Work out your protein and fibre targets.
3. Stay on your current dose for now and start tracking calories and macros. This isn’t something you need to do forever, even a month or so can give you a baseline and help you understand what your portions need to look like now. Where you can, reduce refined carbs, added sugar, sweeteners and UPFs, and make small, sustainable swaps to whole foods.
4. Build up your hydration to at least 2L of water a day
5. Move more if you can (for muscle preservation rather than weight loss)

Then give it 2–3 weeks and see whether working with the medication is actually helping satiety and food noise. If you’re still not noticing any difference, you can continue with the changes you’ve made and consider moving up to the next dose.

For me, it was actually the more subtle effects of the medication that made the difference and supported me through my weight loss over the last 2+ years. I’ve now maintained for the last 9 months, something I’d never been able to sustain previously.

Good luck

From the links I read, Novo decided on the dose strengths and a 30m minimal window as consistent compliance of a longer fasting window would be difficult.

So the dose strength, fasting windows are what was followed through in the trials and are in the instructions. There are some small studies (if you google or ask ChatGPT they are fairly easy to find) that show waiting longer increases concentration in body (such as this graph), but they don't go as far as trials to find out if they give genuine results.

I am feeling the same!

Did 4 weeks of 1.5, on second week of 4mg and lost absolutely nothing

Feeling quite fed up and wondering if there is any point keeping going and trying the 9

Everyone else on other threads seems to be losing so easily so I totally get how disheartening it is!

Exactly this! Unfortunately due to the negative press MJ and W receive, people seem to mistakenly think that you just pop a pill or jab and the fat melts away! They aren’t going to work unless you are in a calorie defect, eating a healthy diet and massively increasing protein. Yes they reduce food noise (for most people) and can stop you eating as much but they are just a tool to help people make the right choices. The not being able to eat stage only usually happens when you first start or increase a dose. If you expect them to be a magic pill where no effort is required then you’re going to be disappointed! You need to try calorie counting, increasing your dose etc before claiming that they don’t work.

I’ve noticed this, there is another thread asking what people think of wli. And a poster is havering on about people not changing their eating habits. I Reallu think many people don’t understand the medication and think you inject and the fat melts off, they don’t understand you need to proactively diet, the meds just enable you to do that and stick to it.

if you want the medication to do the heavy lifting, then you’re in a lot of trouble, as you will need to be on a high dose forever.

howver the op is feeling no impact at all, so for her right now, she’s on too low a dose, or she’s one of the 20 percent where they simply have no impact. The pills though are significantly less effective than the injections.

howver the op is feeling no impact at all, so for her right now, she’s on too low a dose, or she’s one of the 20 percent where they simply have no impact.

I can only speak from my own experience. If I don't work with the medication or if I slip back to the diet I had before (sugary cereal, carbs, ready meals, out of routine over Christmas the last two years) I quickly get cravings/food noise and hunger again and it feels like the medication is doing nothing for me. I can easily, using the ops words "eat a massive meal" if I want to and at times I do.

For me I need both the medication and the changes working in tandem to get any benefits - if I changed to a different GLP1 I would personally not be looking at a dose increase a this stage if I hadn't set myself up for success by trying to put in place the basics first.

Are you trying to reduce your food and eat healthy? Or do you just expect the pill to melt the fat…because that’s not how it works

I dont think its unreasonable to expect the pills to do the heavy lifting

thats what the injections have done for many. And it’s why loads of people have been overweight all their lives but suddenly found it easy to shed the pounds

whilst my appetite is definitely surpressex, im still able to eat enough calories a day to stay the same weight

i want a life that doesn’t include calorie / macro counting. It’s not worked for me before. It’s depressing.

Unfortunately, it simply doesn't work for some people - about 10% - and sometimes that unrelated to your dietary choices. If you are on the highest dose and you aren't losing any, that might be the problem.

@bananaobama - same

if I had the time, bandwidth or inclination to do all the calorie counting, I would!

If I’m paying out this amount I do want the meds to do the heavy lifting and stop the food noise and make me want less

But the people on the jabs have been eating less…if you don’t eat at a deficit you won’t lose weight.

People who do well on the jabs are successful because they are dieting and/or exercising, and they are able to stick to the diet more easily because they have the jab to suppress the appetite.

I jab, and I lose weight…because I am on a diet. I could definitely eat enough not to lose weight, just add a chocolate bar into my diet, and a burger instead of a salad for lunch…but I don’t do that because I want to lose weight. The suppression is what means that a diet I would normally be bored with after 2 months, has now been going for 4 and I’m still going strong.

The suppression won’t happen for all, but if the suppression is happening for you then you have the extra tool to ensure you lose weight, to make dieting easier to stick to…but you do still need to make an effort to reduce your calories to a deficit.

There is definite evidence on the benefits of waiting longer than 30 minutes after taking the tablets before eating and that even having more water or a coffee or tea can affect absorbtionof the tablet. Also about ensuring that your stomach us empty and not taking it either more than a sip of water. This is because apparently ithe tablet can still can be only partially absorbed for up to 90 minutes.
I now take mine as early as possible as we eat dinner early here anyway so can easily get the 8hr overnight fasting period in.

Luckily I tend to wake about 5am anyway for a bathroom visit most days and can drop back off again fairly easily so its not really a problem to wait until about 7 or 8 am for a cup of tea. And I usually dont eat until mid morning . I certainly have noticed good appetite suppression on 9mg and just have now have brunch and dinner most days. I have lost just over a stone so far on the tablets but have just ordered the 25mg as I still have a way to go.
Ill post a link to an article that I posted previously on another thread, next

This is the article .
www.simpleonlinepharmacy.co.uk/health-advice/weight-loss/wegovy-pill/why-cant-i-eat-after-wegovy-pill/