Anyone had UTIs while taking Mounjaro, or is it unrelated? Scared to take next dose

[Harriette678]

I had a recent UTI which was hell and it’s taken over two weeks to settle. First time in years and it was random. Not to do with sex so don’t know how I got one.

I didn’t take my Mounjaro last week as I was feeling poorly. I unfortunately read too much Google and found some people have had utis or sparked chronic ones after mounjaro use. And now I’m much better and want to take my next dose. I’m all of a sudden terrified if I take it again I’ll get another uti. I’ve been on it 13 months.

should I just take it or has anyone else experienced similar? Yes im highly anxious esp with health but im doing so well with mounjaro, im in maintenance and would orefer to stay on it but i dont if it means ill get another uti or symptoms return.

Getting a UTI from sex isn't the only way to get a UTI, there are lots of mechanisms that are totally unrelated to that.

I can see why people want to connect every other health issue to the medication that they're taking, but it doesn't make much logical sense. I take other medication long term as well as Mounjaro, I don't ascribe every health issue that I get to that medication or to the Mounjaro.

Stopping taking Mounjaro won't guarantee that you'll never get another UTI. It will likely mean an end to your weight loss though.

Continuing taking Mounjaro won't guarantee that you'll never get another UTI. It will likely mean that your weight loss will continue though.

Which of those two options would you prefer to happen?

ideally stay on mounjaro. It’s just been such an awful few weeks. Just worried.

I was of the impression most uti’s were from e-coli, so stool/improper front to back wiping.
I would continue with wli as most likely unrelated.

I got a UTi after two weeks on mounjaro. It came on suddenly and aggressively and was really scary. I was so unwell and had to go to the walk in centre urgently for antibiotics. It was definitely connected to the mounjaro (in my opinion) as I haven’t had a UTI for 10 years previously. It scared me so much I didn’t continue with mounjaro. I’d been drinking SO much water for the whole two weeks as well, so it wasn’t down to dehydration. I did do some research afterwards to help me decide whether I should continue on mounjaro and there are studies that show a link between Mounjaro and UTis . Unfortunately I was one of the people it affected.

You have been on MJ for over a year - if the two were linked, for you, I would have expected this to happen much earlier.

Can you give us some references to these studies as I’ve looked into it and can myself find no studies that show any link at all

I saw a urologist about UTIs and minor kidney issues. She was clear there was no known link between GLP1 and UTIs. They are protective of kidney function as well.

There is no way the medication causes a uti. As a pp said, people do seem to think every single ailment they get when on the meds is down to the meds, like they become super human and can’t get sick normally, it’s incredibly odd, as logic and basic common sense would say this is impossible, how would it cause a urine infection?

Here are a couple of documented studies below that show a link between MJ and UTis. As the studies highlight, there is a scarcity of official data on this issue, addressing unusual urinary reactions. This highlights a critical gap in the current literature, particularly given the rapid expansion of GLP-1 and their use.

Informally, there are lots of Reddit forums discussing user experience with MJ and UTis in people with no underlying renal problems. To read these just search on Reddit.

https://pmc.ncbi.nlm.nih.gov/articles/PMC11454838/

pmc.ncbi.nlm.nih.gov/articles/PMC12914309/

I can believe that - if you have constipation or diarrhoea as a result of the jabs - there might be a knock on UTI if going to the loo is less straightforward in general.

ETA x-post with the link to the studies

Just starting a painful UTI - I have had to up my HRT because my vagina feels drier. I think the meds do affect the pelvic floor, my irritable bladder is worse and I will stop after my 3 month course because I can’t cope with migraines from under eating. I am on semaglutide not MJ.

If you are really anxious and scared about getting another UTI @Harriette678 then stop taking the Mounjaro and in about 30 days it will all be out of your system. Then you definitely won't get a UTI that's been caused by being on Mounjaro. Of course, you may just get another UTI anyway, but at least you'd then know that it isn't related to the Mounjaro.

I can see why that would make you nervous, especially after such an awful UTI and with health anxiety in the mix. Speak to your prescriber before taking the next dose, rather than making the decision based on things you’ve read online. They can look at your symptoms and medical history and help you work out whether continuing in maintenance is appropriate

Did you see a doctor to have a water sample tested for infection?

So I’ve read those case studies. Neither of those show a link between Mounjaro and UTIs.
The first describes a case where a 59 year old man suffered kidney failure, no UTI.
The second describes a case where a 40 year old man suffered some sort of reaction to the drug where infection was specifically ruled out, again no UTI. That paper also says that randomised controlled trials and meta studies have identified no increased risk of UTIs from the use of Mounjaro.
So I still haven’t seen any evidence of a link between Mounjaro and UTIs. Experiences being discussed by posters here or on Reddit aren’t evidence of any causal link, they’re just people discussing problems they’re currently having.
UTIs can be extremely unpleasant, I wouldn’t dispute that, but I remain to be convinced that the use of Mounjaro increases the risk of getting one.

It’s also worth noting that any sugar in your urine increases your risk of a UTI significantly. Type 2 diabetes medication can do this, such as Dapagliflozin and Empaglflozin. Increased UTI risk is a known side effect of these drugs.

Mounjaro will reduce urine sugar.

I haven’t heard of this as a side effect. I have been taking for 21 months and know plenty of other people on it.

Horrible for you but I think it’s a coincidence.

The link is not a conventional “report” or trial. It is a very short conference case abstract about one man, and the clinical story is much less dramatic than the title: prolonged vomiting and diarrhoea caused severe dehydration, which temporarily injured his kidneys and improved promptly with fluids.
This is consistent with the current prescription information that warns nausea and vomiting is a side effect for some users.
Importantly it is NOT a documented research paper linking MJ with UTIs !

As for the second report. In its own words.
“Tirzepatide might rarely produce urinary or pelvic symptoms that mimic a UTI, but this report provides no evidence that it causes bacterial UTIs.”

Again, another report of a single male having a rare reaction is not evidence of a link . The paper acknowledges that larger trials and pooled studies have not demonstrated an increased UTI risk with tirzepatide.
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@HaleyMorgan - another post virtually identical to one you made on a different thread. Are you a bot? Will you answer?