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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Anyone else doubled their 2.5mg dose to 5?

12 replies

Frrrout · 08/09/2026 21:06

I’ve been on mounjaro for 4 weeks, 2.5mg. Had some side effects for first 2 weeks, all ok by week3 and by week 4, very little suppression and all of 0.5kg weight loss. Stupidly, when I ordered my next dose just after dose 4, I got all weird and worried about side effects at 5mg so ordered a further 2.5mg pen. I have regretted it since, as for the past two days I’m back to having my usual appetite.
I don’t want to waste a pen, so I have considered having 2 x 2.5mg doses to make a 5mg pen ( using 2 different sites), then order a 5 mg pen from now on if that is well tolerated and carry on as usual.
Has anyone else done something similar?

OP posts:
purplepie1 · 08/09/2026 21:36

I am on week 6 of 2.5 mg and this week is the first week I have actually felt hungry quite quickly after eating. I had forgotten what it felt like. I still have another 3/4 shots from this pen as I managed to get 5 from the first pen. I will see how the rest of this week goes but if im still feeling the hunger pangs I might increase the clicks to 3.75mg for the last two jabs from this pen. Then I will go up to 5mg.

Frrrout · 08/09/2026 21:42

Thanks @purplepie1,that’s a great idea. I’ve only used my thighs before now as I read it was better tolerated in the thigh, so tonight I’ve used my stomach, but I’ll do the same and move to 3.75 next week if no joy and at least get 3 weeks.
So stupid question, presume you give a full dose wound to 1 to get 2.5 then withdraw and reset by counting clicks to get the last 1.25? Is there a good resource for finding out how many clicks that is please?
(Sorry, new to this and a bit crap at it, clearly!)

OP posts:
MoneyJo · 08/09/2026 22:03

There's a click calculator on the monj.co.uk website.
https://monj.co.uk/mounjaro-click-calculator/

DumpedByText · 08/09/2026 22:38

Try 3.75mg, Google how to micro dose from a 5mg pen, I did 3.75 for 4 weeks with no side effects.

Frrrout · 08/09/2026 22:55

The issue is I have a 2.5mg and should have ordered a 5mg. I figured a double dose would just mean I get through the pen in a fortnight and the dose should be identical but for some illogical reason I’m paranoid about doing it because when I asked AI it said not to 😩

OP posts:
MoneyJo · 08/09/2026 22:57

You absolutely can do it.

SilenceInside · 08/09/2026 22:59

AI is not a great source of help with medical information and anything it tells you should be clear that it is not able to give specific medical advice. All it’s doing is summarising what information is available from (mostly) reputable sources. Those sources will all say to follow the manufacturer guidance, so no variation on dosing, no click counting etc etc. AI is not an authority on anything.

If you are really struggling on the 2.5mg then you could do as you’ve suggested and double dose for 5mg and order a new 5mg pen as soon as your pharmacy allows it.

madeinthe80z · 09/09/2026 06:25

You could do it as a split dose rather than on the same day. So you could do 2.5mg and then another 2.5mg 3.5 / 4 / 5 days later rather than 2 injections on the same day and a straight jump up to 5. There’s a few options but also see how you get on this week with your 2.5. In the earlier days I found some weeks were different to others, better suppression one week and the. Rubbish the next. There’s some factors which affect it, including your cycle and what you’re eating and drinking etc.

morbidcuriosity · 09/09/2026 09:18

Try 2.5 every 5 days until you get your 5 pen maybe?

Takemeawayy · 10/09/2026 11:23

I am on my second time round with Mounjaro and had to start at 2.5 but I am doing it every 5 days which seems to be working for me.

5289843DM · 10/09/2026 11:39

2.5mg to 5mg is the only time in the regime that you double the dose. I didn't want to just jump to 5mg having read about others having ill effects- not always, but I wanted a smoother transition. I used the golden dose in the 2.5mg pen, it was only about 3.8mg but my goodness, I had awful side effects. D&V and felt dreadful the entire afternoon. No idea why and I've never had a reaction like that since.

I bought a 5mg pen as the 2nd pen, (I know you didn't) and used the click dosing. I 'think' I did 3mg, 3mg, 4mg then to 5mg with no issues at all. As soon as I could move up, I always bought the next strength pen so I could do this. I'd do similar with the 2.5mg pen- give a 2.5mg dose- inject, then click to add say 0.5mg and inject.

Cheesecake53 · 10/09/2026 15:25

@Frrrout the link @MoneyJo posted is really good, is shows how many clicks, but also how many ml these are and you could take these out with a syringe - like a golden dose.

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