Best Amazon Prime Day deals: Mumsnet favourites

Best Amazon Prime Day deals:
Mumsnet favourites

Shop now

Please or to access all these features

Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Has anyone found Mounjaro less effective when restarting after a break?

5 replies

Cornishbelle · 20/05/2026 11:45

Hi I've just restarted mounjaro after a five month gap, I titrated down and came off completely in January due to the cost, and I've already put a stone back on! I took my first 2.5mg Sunday but have not felt any suppression yet which was almost instant first time around. Really hoping to be successful this time just wondering if anyone can share experience of restarting

OP posts:
boundtobe · 20/05/2026 17:58

I've read that most people need to get back up to at least the dose they were on before stopping before feeling the effects.

Brenda782 · 02/06/2026 21:48

I restarted Mounjaro after a break too and the suppression definitely felt slower the second time, but it still worked for my weight loss once I got back into the routine. I’m using a medically supervised programme now which made me feel a lot more comfortable restarting, plus it’s been more affordable for me this time around 🙂

badboss2020 · 02/06/2026 22:11

I started on wegovy after a break from mounjaro and it’s done nothing for 3 months. Such a waste of money. I’m on 0.5 now so maybe the next step up? Otherwise I’m giving up.

Twoshoesnewshoes · 02/06/2026 22:18

I’ve only ever used it for one month at the lowest dose so my experience may not be very useful.
i also found suppression from day 1 first time around.
i went back on after i think six or seven months - two weeks and nothing except a (perhaps placebo) craving for sugar. I gave up!

Johnnyfartpants · 02/06/2026 22:19

I gave up on MJ because of the cost (had lost 4.5 stone) - went on We Govy which had zero effect and I have put on 2 stone now :(

Back up to 7.5mg of MJ and only now starting to feel even slight suppression, even though the weight loss last time was right from the word go.

New posts on this thread. Refresh page