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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

5mg too little, 7.5mg too much

10 replies

Tranquilitybaby · 07/02/2026 02:08

I’ve been on Mounjaro for 11 months now, three stone down. Slow but steady.

Having not really lost much weight since Christmas on 5mg, I decided to do 7.5mg a few days ago. I’ve felt rubbish ever since - no appetite, nauseous, can barely eat more than about 6 bites of food at dinner, yet 5mg was doing nothing.

Unsure where to go from here, I want to lose at least another 14-21 lbs.

anyone else has this?

OP posts:
SooooAIBU · 07/02/2026 04:39

I would try 6mg and see if that works.

VashtaNerada · 07/02/2026 04:42

I use a 7.5 pen but have 3mg twice a week.

lovealongbath · 07/02/2026 05:28

move up slowly….

from a 7.5mg pen -

5.5mg is 44 clicks
6mg is 48 clicks
6.25mg is 50 clicks

LizzyTango · 07/02/2026 05:43

7.5 but inject every eight days.

SchoolDilemma17 · 07/02/2026 07:02

I’m in the exact same position. Can’t deal with 7.5mg. Also have the last stone to lose, lost 4 already. Staying on 5 for now and have uppes the exercise. Losing very slowly atm, but I guess better than nothing.

Herewegoagainandagainandagain · 07/02/2026 08:03

DottyMcDiet · 07/02/2026 07:00

Why jump from 5mg all the way to 7.5mg?

I only take what I need for adequate suppression and am currently on 6mg.

https://weightlossuk.co.uk/mounjaro-click-chart/

I’m hoping you didn’t mean that to sound as judgy as it reads 🤔 Following the official dose steps is not unusual.

@Tranquilitybaby The steps ups relatively speaking on the lower doses can hit hard. It might just take a couple of weeks for your body to adjust or stepping back to previous dose or mid way are options depending on you risk tolerance.

As you have been on it for 11 months I'll assume you are already aware of click counting, but if not some suggestions have been given.

Hope you feel better soon.

Boots89 · 07/02/2026 08:09

When I moved from 5 to 7.5 I felt unwell for a couple of weeks I think its normal when moving up any dose. I got all the way up yo 12.5. I've lost just over 7 stone in 12 months on MJ.

janedoe26 · 07/02/2026 08:11

Lots of options if you are happy to diverge from the prescribers instructions OP.

You could take 5mg every 5-6 days. That’s 40 clicks from your 7.5pen. Or if you prefer to stick to the weekly dosing schedule then take less. Half way step up from 5 to 7.5 is 6.25mg which is 50 clicks from your 7.5mg pen.

as well as finding a level that works for your without being too high in side effects, any of these options have the bonus of being better value as you will get more doses per pen. Just keep in the fridge always and v strict with hygiene and checking fluid stays clear.

nevertoolater · 07/02/2026 08:51

I’ve had the exact same problem OP. I was on 7.5mg for 5 months and then all of a sudden started struggling with nausea. I dropped to 5mg over Christmas but felt really hungry and I quickly gained 5lbs.

I’m now back on 7.5mg because to be honest, the nausea is better than the scary feeling of not being in control. So far so good but I’ve carefully looked at my diet. I’m upping the protein and avoiding anything too fatty. I’m also just eating small amounts regularly and being really strict about water intake. I’m not really hungry but don’t feel as permanently sick as I did.

Perhaps try 7.5mg again but tinker about with your diet and see if anything you’re eating (or not eating) is affecting you.

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