Monjaro Wearing off after a few days

[NextDoorButOn]

Has anyone else experienced this. I’m only 3 weeks in, but each time I jab I have some appetite suppression. Then on days 5 and 6 I want to gnaw my own arm off.
If you have had this did it go away eventually or on higher doses?

Month one, on 2.5mg, your body is getting accustomed to the medication. Some people experience very little suppression, some experience a lot. Going up to 5mg, in month 2, should help. My friend is on a maintenance amount of 7.5mg and she is often hungry.

Completely normal. The medication has a 5 day half life.

You may be feeling extra hungry because the medication is wearing off plus you might have eaten so little in the previous days your body needs fed. It is worth tracking your food in the first couple of months and monitoring your eating patterns - calories and macros are both important.

If you are not already, try to work with the medication and increase your protein, water, fiber etc and it will help towards the end of the week. Add in a protein based snack on those days. Also look at your calorie deficit over the week rather than daily, you can calorie cycle / eat a little more towards the end of the week.

You’re basically on half a dose, just intitiating treatment, before you go to the first full therapeutic dose of 5mg. Some peoples get full suppression, some get none on 2.5.

you just need to ride out the month, mounjaro is not a quick fix. It is a long journey, and this is normal.

Can you take a second 2.5 dose after 5 days?

This is normal, 2.5mg only worked 2 weeks for me then completely stopped for suppression, satiety and managing food noise. I had to go up to 10mg before it gave me all the required benefits all week long and then it only lasted 7 weeks. You could benefit with moving upto 5mg. What I didn't know back then 14 months ago was a high protein, low carb diet and plenty of water would keep me fuller for longer. I was also prediabetic so the doses wore odd quickly for me until I got to a lower bmi and my natural insulin sensitivity kicked in. Then I went back down the doses as they were too high for me.