Mounjaro 2.5mg every other week?

[greenspaces03]

Hi I’m just about to start. I was wondering if starting on 2.5mg every 2 weeks (or 10 days) has been attempted by anyone?? How did it go?

I know someone who follows this regime to maintain. Not sure it would be enough to lose on but worth a try I guess! Are you thinking it’ll save ££?

The half life of the medication is 5 days which is ideal for 7 day dosing.

What is your driver/are you trying to achieve by injecting every other week?

I started on 1.25mg so a half dose per week. This was a restart after finding 2.5mg was too much for me initially due to really bad sides, which I would point out doesn’t seem to be the norm for most people. I think 2.5mg per fortnight would mean that you’re not keeping a consistent dose which might be unpleasant. What is your reason for considering it?

if helpful I take 2.5 once a week and have never gone up. My appetite is definitely suppressed and I’ve been losing 1lb a week since the start. I don’t have side effects and feel well and normal. It’s working very well for me.

Go for a small dose weekly if you want to use less

It’s a prescription medication. You should take it as prescribed and see what the effects are and how it works for you before changing the dosage schedule.

Why though??

@greenspaces03 there is someone on another thread who did this to minimise side-effects

I've been scouring around because I've had problematic side effects from the start

That's probably my next step as well

I took a break last week because I wasn't sure I was going to carry on, then took it two days late. So far, I don't have an upset stomach. Fingers crossed.

Try Reddit there is lots of information there

ask your provider, I bet they'll say it's fine though obviously they want the money they don't want you to give up on the med

It’s the side effects I want to minimize really hence the protocol. I have just 10kg to lose. Worried about side effects

How are you getting it with only 10kg to lose??

Let me clarify. I weigh 100.7kg and my BMI is 36. Personally I only want to lose 10kg. Medically I should ideally weigh 75kg or so @ShawnaMacallisterhope this clarifies

@greenspaces03 there is a website where you can enter details of doses and see a graph that shows an estimate of the amount of medication in your system over time - https://glapp.io/tools/glp1-plotter It can be useful to visualise how the medication will rise and fall after each injection.

Doing 2.5mg every fortnight results in higher peaks and lower troughs, so a more spiky profile compared to 2.5 each week. 1.25mg each week produces lower peaks and a more stable dose level. Anyway, you can try out various options and see what you think.

Thank you @SilenceInside🤗👏

Ive done 1.25mg every 7 days and it worked really well for me. After 4-5 months i moved to 1.25mg every 5 days. Then 1.75 every 5 days and now (9 months in) im doing 2.5mg every 5 days. I have lost a bit more than 3 stones and i have one stone to go which im confident i’ll achieve with this dosage (and careful eating + lots of physical activity). Then i’ll start decreasing the dosage again and perhaps extending the time between the doses again…

Thanks @Placestogohow did you microdose with 2.5mg needle and supply?

At first yes but now im using a 7.5mg pen as this is what i am most comfortable with (and economical). I dont want to get a bigger pen as i would worry about the number of punctures in the seal and the extended life of the pen. A 7.5mg pen last me about 2.5 months (incl golden dose) and about 15 punctures (one for each dose - regular or golden) which i am comfortable with. Longer than that and i would start worrying.
i am using this calculator to check clicks etc…https://mounjaroclicks.co.uk/

Thank you!

Not much point… you’ll be letting it run out of your system a week before the next dose hits.

Not how it works
Use the plotter

it can stay in your system for about 30 days

@greenspaces03 I wish I had taken your approach from the start

This time I've had a 10 day gap and now is day two. I don't feel half as bad as I usually do on day two. It hasn't affected me doing things, it's manageable - but I have found the whole experience not pleasant.

So I think my next dose is gonna be 10 days time and it's gonna be lower.

You haven’t even started yet so maybe just take it as prescribed and see how you get on? Lots of people don’t even get much from 2.5mg (I did I have stayed on it for over a year and lost 8 stone) so if it isn’t effective you would literally be throwing money away. I think start as you are supposed to and if you do suffer side effects reassess. You can try to minimise SEs by eating a clean and healthy diet and staying well hydrated too.

This is more akin to the microdosing strategy that I and others on here have been doing. I started on 1mg a week and have seen good results just from that. No major side effects and fairly rapid suppression/weight loss.
Have regained some of the weight (around 5lb) since I stopped though; however that could be because I let my weight get a bit too low for what I could sensibly sustain.

I’ve been doing this for a few weeks now in order to maintain. My maximum dose was 5mg during my weight loss phase and I’ve been titrating down.

I was still losing on 2.5mg every 2nd wk before Xmas - but that was partly because I am very anxious about regaining and was probably being too controlling. I’m not sure I feel much of any suppression in my second week after injecting and my losses are because I’ve been retraining myself since last April.

I don’t understand why you wouldn’t start with the recommended dose and see how you get on to begin with though. Whilst lots of people respond well to 2.5mg (I lost 2 stone on it) many don’t get much effect at all. I would try it as it’s supposed to be used initially and then tinker with it if and when you find suppression too high on 2.5mg.

Something to consider - this medication has been through actual clinical trials by actual professionals, doses and a dosing schedule designed to maximise effectiveness and minimise side effects and that’s usually a sensible place to start.

If that doesn't work out then perhaps look for some sensible suggestions, but honestly, going into it with an armchair pharmacist mentality is not wise.