I've read in a few places that 2.5mg is a starter dose to get bodies ready for true suppression. I've just started my second pen and doing pretty well on it. But I'm having a busy August and earlier this week met up with an old friend for a delicious meal out. Margo in Glasgow if you are interested- amazing place. So I thought I was being careful, ate as healthily as possible. Went to bed happily that night and felt fine. Until about the same time the next night when I had all the bad effects I've read about at one time. Sulphury burps, nausea and of course the dreaded cramps and the need to "go" as quickly as possible. However my biggest problem was that this happened when I was in the middle of Murrayfield Stadium watching Oasis. I still had a fantastic time and just about managed to hold on to my dignity, but lesson learned, I guess.