Lost 6 pounds in less than a week after first injection. Is it safe to lose this much so soon?

[JuststartedWLI]

Hi all. I had my first Mounjaro 2.5mg dose on Monday (6 days ago). I stood on the scales today and my weight was down to 13 stones 7 pounds. I was 13 stones 13 pounds just before I injected the first dose. I am very pleased with the weight loss so far.

I've read that losing too much weight in a short time can increase your risk of pancreatitis. Should I be worried? Did anyone else see a significant weight loss in their first week?

I think most people would lose like that week one if you have changed your diet significantly and not dieted before. It's usually glycogen stores rather than fat. It should settle to a pound or two a week after the initial whoosh.

I had the same and for me it didn’t continue like that. It was just the initial water weight that you hear about. I’ve now been on mounjaro for 14 days and have lost 5 kgs. Just give it more time.

I was the same starting weight as you op and lost about the same amount first week....it's slowed down considerably now.

Any weight loss in the first week of a significant change in calorie intake will see a massive loss depending on how overweight you are.

Out of that 6lb, 4lb is probably 'water weight' as they say, the stuff making your liver stiff.

Yep 1st couple of weeks a large weight loss wouldn’t be surprising. It’s if it carries on week after week. Up to 2lb a week loss after the initial few weeks is safe.

I lost 9lbs in the first week, a great confidence boost. Eating sensibly since then I lose about a pound a week, so I wouldn’t worry at this stage, just enjoy the good start.

Totally normal in the first couple of weeks. It will slow down so don’t panic.

Yes, I’ve lost that much in a week on SW and with fasting too.

It likely won’t carry on at that rate.