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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Restarting @2.5mg - what to expect!

12 replies

Bossingit67 · 24/05/2025 14:00

I have been on MJ But took a break due to finances and a few other reasons. I’ve decided to go back on it and I am starting again at 2.5 mg. I guess I’m curious to hear from other people as to how they have got on when they have taken Mounjaro before stopped and then gone back on it?? I took my jab yesterday and so far not much effect , but I am well aware that this is normal. Last time taking it from about three days after the jab is when I had the most suppression and I did get good suppression on the starter dose. Just hoping that might be the case again this time!

OP posts:
hoarahloux · 24/05/2025 17:55

How long have you been off it for? And what strength were you on when you stopped?

I had a month break and it's only working again now I'm at 7.5. Finally losing again, albeit slowly.

A longer break will probably mean it'll work better.

Bossingit67 · 24/05/2025 19:36

It’s been 4 months , I was fine on 5mg with suppression but it was starting to wane but I was due to go up to 7.5

OP posts:
Bossingit67 · 26/05/2025 09:04

Just a quick update… I’ve definetly had some suppression. I can still eat but I feel fuller quicker!

OP posts:
MamaorBruh · 26/05/2025 13:15

These posts read through exact same as mine last week - I had to check I wasn't reading my own post 😅

I stopped 4 months ago and started again at 2.5mg a week last Sat.
So I'm on W2D3.

Sadly the alcohol refusal I got during my first set, isnt there! Meaning I'm probably getting my calories from wine as I'm not eating much.
Ive only lost 4.5lb so far wheres it wad more last time after 10 days on it.

Going to try stay of the wine this week which should be ok as its half term so no plans to be drinking.
Good luck; let me know how you get on!

Bossingit67 · 26/05/2025 16:25

@MamaorBruh ahh thanks for your message it’s really nice to hear someone’s opinion who is in the same boat! So this is actually the 3rd time I’ve been on Mounjaro but my break the first time was only about 6 weeks. I’m getting more suppression than I did when I restarted after a 6 week break so that is something I guess!! I never found it put me off alcohol which is annoying !! I feel like the suppression is not so much as first time but I’m definetly getting something and didn’t really want much dinner last night !! Are you getting any food suppression? I’m still liking my food but just feel like I’m fuller for a lot longer this past 24hours more than the day after I took the jab. As I remember tho around 48 hours after jab is when I got most effect . Mine tends to wane about day 5, fingers crossed it works for you - 4.5LB is not a bad loss but it’s hard to not compare it to how much you lost at first isn’t it! I lost a stone pretty quickly… prob in about 8 weeks?!!

OP posts:
MamaorBruh · 26/05/2025 18:27

Bossingit67 · 26/05/2025 16:25

@MamaorBruh ahh thanks for your message it’s really nice to hear someone’s opinion who is in the same boat! So this is actually the 3rd time I’ve been on Mounjaro but my break the first time was only about 6 weeks. I’m getting more suppression than I did when I restarted after a 6 week break so that is something I guess!! I never found it put me off alcohol which is annoying !! I feel like the suppression is not so much as first time but I’m definetly getting something and didn’t really want much dinner last night !! Are you getting any food suppression? I’m still liking my food but just feel like I’m fuller for a lot longer this past 24hours more than the day after I took the jab. As I remember tho around 48 hours after jab is when I got most effect . Mine tends to wane about day 5, fingers crossed it works for you - 4.5LB is not a bad loss but it’s hard to not compare it to how much you lost at first isn’t it! I lost a stone pretty quickly… prob in about 8 weeks?!!

Ive got a lesser appetite for sure, but Im struggling with the alcohol thing as that's definitely my downfall.
Last time it never appealed to me at all plus when I did have the odd drink, the heartburn was so bad that it put me off even more!

Bossingit67 · 26/05/2025 19:51

I wish it had the effect that I didn’t want wine but unfortunately not!!

OP posts:
MamaorBruh · 30/05/2025 10:58

Bossingit67 · 26/05/2025 19:51

I wish it had the effect that I didn’t want wine but unfortunately not!!

That effect seems to have disappeared now!

This is waaaay less effective than it was the first time round.
I haven't stopped eating this week and have actually put 0.8lb back on! Its ridiculous.
Ive taken my 3rd jab this morning then I may go to 3.75mg next week as there will be enough left in my pen.
Just hope it has a good effect.

I will be honest, I've not drunk anywhere near enough water so need to up that too.

How have you got on?

Bossingit67 · 30/05/2025 11:45

Hi @MamaorBruh ! Nice to hear your update altho sorry it’s not been going to well!! So I’ve not lost this week maybe 1/2 lb. The suppression has actually been ok for me not ‘amazing’ but I’ve just been a bit lazy and drunk too much wine! I’ve def not been as hungry. I’m getting more suppression than when I started again after say 1 month tho so maybe the longer breaks helps reset you more? I’ve just done my second dose of 2.5 I’ll be doing the magic 5th dose of 2.5 and going to 5 altho I may step up to 3.75 before fully going to 5 if it’s working for me xx

OP posts:
MamaorBruh · 30/05/2025 12:09

Bossingit67 · 30/05/2025 11:45

Hi @MamaorBruh ! Nice to hear your update altho sorry it’s not been going to well!! So I’ve not lost this week maybe 1/2 lb. The suppression has actually been ok for me not ‘amazing’ but I’ve just been a bit lazy and drunk too much wine! I’ve def not been as hungry. I’m getting more suppression than when I started again after say 1 month tho so maybe the longer breaks helps reset you more? I’ve just done my second dose of 2.5 I’ll be doing the magic 5th dose of 2.5 and going to 5 altho I may step up to 3.75 before fully going to 5 if it’s working for me xx

Perhaps it just needs a bit longer for my system to get used to it again?
I'll order another pen and see how I get on with that.
And will up my water intake!

Bossingit67 · 30/05/2025 14:56

@MamaorBruh im just so bad with water ! I’ve seen so many posts about people never getting much from a 2.5mg loading dose as it’s more to get your body used to the drug. I think like me if you have had previously good suppression on 2.5mg then you kind of are disappointed if you don’t get it again. Not sure how I would have felt if I had had no suppression from 2.5mg at the start of ever taking it… might have put me off ? I feel like I’m getting some suppression today but I eat when I am bored or because I like the taste not just for hunger so managing that is hard! X

OP posts:
MamaorBruh · 30/05/2025 15:02

Bossingit67 · 30/05/2025 14:56

@MamaorBruh im just so bad with water ! I’ve seen so many posts about people never getting much from a 2.5mg loading dose as it’s more to get your body used to the drug. I think like me if you have had previously good suppression on 2.5mg then you kind of are disappointed if you don’t get it again. Not sure how I would have felt if I had had no suppression from 2.5mg at the start of ever taking it… might have put me off ? I feel like I’m getting some suppression today but I eat when I am bored or because I like the taste not just for hunger so managing that is hard! X

Edited

Yes, that's the same as me - eating through boredom (and part hunger!)
Need to snap out of it.
Yes good point re first time - I'd have been super disappointed in this.

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