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Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

Has anyone started MJ who has existing digestive issues/reflux? Scared of them getting worse!

31 replies

redcherrybottle · 26/04/2025 23:23

I really want to try mounjaro but I’m scared to aggravate my existing digestive issues.

i get regular bloating, heartburn and bouts of nausea - I think probably GERD or similar. Have had a prescription of lansozprazole which has reduced the symptoms.

would love to hear from others with similar symptoms.

OP posts:
JG1586 · 09/06/2025 16:50

I'm the same for years I've took omeprazole every day for heartburn/reflux. Often find myself waking up in my kitchen sleep drinking gaviscon because I'm getting heartburn while I sleep. I started mounjaro last Thursday - after having the same anxieties as yourself but touch wood alls good. Last night tho was quite bad with heartburn but I hadn't taken my omeprazole for a few days so I'm assuming that's where that came from. Thing is with me I'm always refluxy, have crazy stomach acid, it's gonna be there regardless I'm fat or less fat :) I hope this helps :))

Jabtastic · 09/06/2025 16:54

It made mine worse, bad enough that I stopped. I may have been unlucky though.

gimmemounjaro · 11/06/2025 15:05

I have been on omeprazole for reflux for a few years. Since being on MJ I have halved the dose and could probably come off it altogether. I might try every other day or something like that. I’ve only had one episode, which was pretty bad, but tbh it was my own fault for eating too much pizza and drinking too much wine just before bed. I haven’t had any other GI side effects bar the occasional day of eggy burps.

ShrankLastWinter · 11/06/2025 18:05

I’ve been on Omepraxole for reflux for years. On MJ I’ve occasionally had sulphur burps and/or a bit of heartburn after eating (a tiny bit of) fatty food. But nothing particularly bothersome. Now I’m 27kg down and should probably try reducing my Omepraxole dose.

Alibot · 16/07/2025 09:13

Hi. I took Omeprazole for 15 years to manage my reflux symptoms. Hated taking it but given no option. Have lost 35lbs with Mounjaro since last October. Started tentatively reducing my Omeprazole about 3 weeks ago. Have now gone 5 days without taking one and guess what - absolutely NO reflux symptoms!! It seems like a miracle, but researching online there is a lot of evidence that weight loss reduces pressure on the stomach and lower oesophageal sphincter and thus prevents acid from being forced up. Feeling wonderful and so relieved if this really is the end of gastric reflux . . .

Rallentanda · 16/07/2025 11:12

I'm not very far in, just been taking it for a week, but to my surprise my acid reflux (which I assumed was related to weight) has reduced by about 70%. I'm on 2 or 3 Rennie's a day and that's it!

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