Big itchy red mark where I injected (Mounjaro)

[MounjaroUser1233]

I've never had this before; this is my 1st week on 10mg so week 13 of doing MJ and I have done Ozempic for about 6m a couple of years ago also.
I have always injected into my belly. But this time I injected a big closer to the centre / navel as opposed to the side / love handles area. It is insanely itchy and about 2 x 1 inches. I think I might have injected onto or near a stretch-mark. Could this be why it's caused this reaction? It's been 24 hrs now and if anything it's looking redder than it was yesterday!

It’s a common side effect, anti histamines and anti histamine cream You will likely get it every time now, for the next few weeks. It’s an anti histamine reaction,

Yeah a lot of users develop a histamine response, it's quite annoying! Anti histamines as pp said

I often get this, mostly on the 5 jab.

Antihistamine tablet really helped. I didn't have any anti itch cream so I put vagisil on it, that helped too 🤣🤣

Mine just started out of nowhere too after months of using MJ. It happens every time now, some weeks are worse than others. It's itchy as hell.

I’ve had it too. I used Eurax cream which helped. And a few months in it’s not so bad. Only itches for a day or so rather than almost the whole week!

I get this every time I inject now. I put some sudocreme on it and it seems to help.

Same, but have had it with every jab. I get it with my Aimovig as well.

Hydrocortisone cream does the trick for me.

Injecting into my stomach seems to be much less itchy though.

Yep same here from roughly 10mg onwards too. I alternate thighs and the itch from one leg goes when I inject the other side! Then the itch and red patch comes to new leg after a few days, it seems to get worse sometimes as a new injection is due 🤔 but yes a big round, itchy red patch. Thankfully mine isn't too itchy for too long.

Mine started out of nowhere too about 3 months in, and is worst on about the third day after injecting. Happens every time and takes about 2 weeks to fade. Weird how it started all of a sudden - I was freaked out but as others have said, apparently it’s quite common.

Mine started on my 6th injection and only started to die down on my 30th. Now I don't need the pills and might dab on some cream once or twice after the injection.

Antihistamine pills and creams reduce the reaction. A longer needle might help, so 6mm or even 8mm rather than 4mm, but didn't work for me.

Thanks everyone for your replies x
It is so strange for me as I'd already injected 12 times with absolutely no side-effects. But seems like a reaction can start out of the blue and randomly. I wonder what causes it to suddenly make you allergic?! So weird 😕

I think you build up antibodies to it, so the reaction is considered a sign of a working/ healthy immune system.

Oh that's cool! I have very little knowledge of stuff like this so thank you 🥰 x

I’ve posted about exactly the same problem today! I’ve had no reactions in 16 weeks apart from my last 2 where I’ve had this itchy raised red area where I inject. Another poster has suggested it could be to do with the length of the needle. It coincides perfectly to when I changed my provider! I’m going to change needles and see if that makes a difference.

www.mumsnet.com/talk/weight-loss-injections/5254218-suddenly-getting-skin-reaction-at-injection-site?reply=141435666

I’ve just done dose 31 and haven’t had an injection site rash for a while now - can’t remember when it stopped but had it the first time I did my thigh (wk 9) and then went back to abdomen - definitely had it there week 13 through 16 (and I am pretty sure beyond that) at some point it stopped but I also stopped recording my symptoms/things like this so not sure when exactly. I remember trying thigh again and it was worse there so never tried it again.

I had it weekly for 3 months until I started leaving the pen to warm up for 1hr or so before injecting. Was big and very itchy. All fine now!

I got this out of the blue for a few weeks after having no reaction initially. It stopped as quickly as it started after a few weeks, I wouldn't worry.