MJ 2.5mg to 5mg - advice / experiences

[OMarina]

I've been on mounjaro for a month. So far it's been fine and the side effects minimal. I should move up to 5mg for my next dose. Would be really grateful for advice.

I usually take my dose on Wednesdays. However I have to go to on a work trip on Thursday for an all day meeting with clients which I cannot fuck up. Usually I work from home so it's not a worry.
I'm totally paranoid that I'll take the first 5mg dose on Wednesday, suddenly have awful side effects and be really ill. Will it be a problem if I have a break and start it on Friday?

What have been others experiences of moving up a dose? I suppose I'm worried that having been so nervous about taking it, it's actually been fine for the first month and I'm worried I've got a false sense of security!

Thank you in advance

You don’t need to move up if your suppression is ok. We all seem to react so differently to the medication so it’s hard to predict but I had minimal side effects on moving up - bloating was pretty much it!

There would be no problem with you injecting 2 days later than usual but the levels of MJ in your system would be low so you may feel the 5 more than otherwise.

Take an extra week of 2.5 from your 5 pen (30 clicks)

Yeah, get your bonus dose of 2.5mg

if not, then no it’s not an issue putting it off until Thursday / Friday. I’ve moved mine around loads.

I thought it was the thing to do and move up, really the suppression was fine and I should have stuck at 2.5mg for longer.

I was worried about side effects so thought I'd do a mid way step first and I did 3.75mg. I've stayed there for 15 weeks now and suppression is good enough for me with minimal side effects.

How do you feel on 2.5mg? If it is work ok, stick with it. Or stick with it for another week until more convenient to move up.

When you say a month, is that 4 dose done?
If it is, then use the 5th dose of 2.5 for another week then move up to 5 after..

I did 5 x 2.5 dose then went to 5 and was fine, no side effects, apart from constipation, but thats easy to deal with!

I stayed on 2.5mg for 10 weeks and then moved on to 5mg

I was on holiday when due my first 5mg and didn’t want to risk it. Used the 2.5mg from the bonus dose. Have a 5mg pen now but thinking of just sticking to 2.5mg as suppression still strong.

How do you do the 3.75mg?

On a 5mg pen when you dose you turn the dial all the way to the number 1. This is 60 clicks (or a 0.6ml dose).

To get a 3.75mg dose only click 45 times (mark with a biro in the window if you are going to do every week incase you lose count the next time).

If you use 3.75mg from a 5mg pen you will get 5 doses out the pen without having to break it, injecting on days 0,7,14,21,28 within the 30 day limit.

You will still have liquid left in the pen after 5 doses. There is enough for a 6th dose of 3.75mg which could be used on day 35. This is beyond the 30 day limit, so you would need to research and risk assess for yourself if you want to use it, but you would need to break into the pen the access it (hard twist or use a syringe to extract 0.45ml for a 3.75mg dose through the red seal).

Do be aware through that providers will not condone adjusting doses or use of the 5th dose and some may notice/question if you do not order pens every 4 weeks and it could cause problems reordering especially as you go up the doses and you don't have proof of a prescription 4-5 weeks prior. You also don't want to get into a position of stockpiling as you won't know when you will need to move up strengths in the future.

I done 4 x 2.5 then um on 5mg and I think I got more suppression on 2.5

Fab great explanation thanks!!