Negging! Despite many reservations about how TBBT depicts things, one time it did well was when it mocked negging:
Howard: Mock me if you will, but it works. You show up at a club in something distinctive, scope out your target and toss out some negs.
Raj: What are negs?
Howard: A neg is a negative compliment that throws a pretty woman off her game, like “Normally, I’m not turned on by big teeth, but on you, they work.” I’ve got a whole list of ‘em. Who wants to be my wingman?
Leonard: You’re not gonna need wingman, you’re gonna need a paramedic.
Penny (entering): Howard, your scooter’s blocking my car. Aw, did you get pinkeye again?
Howard: Step one, she notices the eye patch. May I say, Penny, not a lot of women could look as hot as you do with such greasy hair? (She reaches out, pulls his eye patch away from his face, then lets go allowing the elastic to spring it back into place.)
Penny: Yeah, just move your stupid scooter before I pick it up and throw it in the dumpster.