Recurrent MC--Testing and beyond--Part 5 continues here

[LAF77]

Here is the list of us on the thread and where we are in our journey through RMC. Nearly 4,000 posts in a year, so mark your place for the next thread.

Part one Part one

Part two Part two

Part three Part three

Part four Part four

STARTING TESTING
LOLA78: mc1 Dec 07 (6wks), DD Oct 08 (problem free pregnancy and natural birth), mmc2 Nov 10 6wks ERPC at 10wks, mc3 Feb 11 at 7wks - suspected ectopic but mc naturally, mc4 mar 11 at 5wks (started 75mg aspirin from a week before bfp) - hospitalised for excessive bleeding and clots. Now referred for testing at local fertility clinic, we have started having blood tests and am on 5mg folic acid.
SCOOTERCHASTER: DS Oct 08 (managed for SVT heart from 35wks), mc1 Sept 10 (7wks), mc2 Dec 10 (9 wks - hb @ 8wks), mc3 April 11 (7.5 wks, hb day b4 mc).
HAIRYLIGHTS, age 42, MC1 (Jun 10, very low HCG, suspected ectopic, methotrexate), MC 2 (Nov 22 2010, MMC,ERPC, no heart beat at ten weeks, fetus 8 week size), MC3 (MMC - Medical Management, Feb 13 2011, MMC at 7 week scan). Waiting to TTC
PANDA 3MMC, no.1 (embryonic loss - empty sac) 7weeks, no.2 at 12 weeks, no.3 at 8 weeks. Awaiting raft of tests for recurrent MC
CLAIREDELOON Age 38 1st mmc, development stopped approx 5 weeks (2007), 2nd mmc development stopped at approx 6 weeks (2009), 3rd mc development stopped at 9 weeks after seeing hb at 8+3 (2010). Bicornate uterus, starting testing Feb 2011.
NOTSOBARRENBROOK Age 35. 1st mmc @ 6 weeks (Jan 2009), 2nd mmc @ 6 weeks (Jan 2010), 3rd mmc @ 11 weeks, development stopped at 6 weeks 3 days (March 2010), 4th mmc @ 5 weeks (August 2010). Possible adenomyosis, awaiting hsg and results of testing from St Mary's.
MILKYWAY2007 Age 28 - DD age 3. 1st MC Oct 2009, 6 weeks. 2nd MMC March 2010, 11 weeks (baby passed away at 7 weeks). 3rd MC July 2010, 6 weeks. 4th MMC 24 Jan 2011, 9 weeks - no amniotic sac, baby measured 7weeks 4 days, no HB, had seen a healthy HB at 7 weeks. Blood clotting, hormone, genetic karyotype and shape and health of uterus checked and all clear. High dose folic acid prescribed.
LUCKYFOR2 Age 32 - DD age 5. DD age 3. 1st MC May 2010 found at 12 week scan passed away at 9 weeks. 2nd MC September 2010 natural at 8 weeks. 3nd MC January 2011 at 16 weeks, saw hb at 13 but no hb at 15.5. All tests have come back clear. Going to take Aspirin and Progesterone in next pregnancy (will be on Promise trial) currently ttc.
IGGI999 - Age 40, 3 year old DS. 3 MC last year, at 6, 8 and 8 weeks. Last two had hb detected. NHS blood tests came back clear, except for presence of antinuclear antibodies. To take aspirin for this. Going to see Shehata in May as think steroids are needed.
CONFU3ED - Age 35 1st MC 1998 14 weeks. DD age 11. 2nd MC July 2009 5.5 weeks. ERPC Twice. No tests. 6 months Clomid 3rd MC January 2010. The foetus sent for testing - came back fine. Been referred to recurrent MC clinic at the hospital for tests, waiting for appointment. Was told I have PCOS through a scan but never diagnosed.

UNDERGOING TREATMENT
HAVINGKITTENS Age 41 - MMC1 Nov 07 8wks (discovered due to bleeding at 10.5wks) ERPC, TOP1 for TS21 Aug 08, TOP2 for TS21 Feb 09, TOP incomplete, ERPC performed, Genetic Counselling & tests confirmed no chromosome problems with us, "just bad luck ", MMC2 Feb 10 5.5wks (seen at 8wk scan, no bleeding), MMC3 May 10 (as MMC2), RMC testing at UCH, no cause found - empirical 75mg asprin & vit D + early & regular scans for next pregnancy, MMC4 No fetal pole seen at 6.5 wks, follow up scan 10 days later, told of MMC, then "Something" spotted so instructed to wait another week before they would allow ERPC, ERPC a week later, waiting for NK Cell test results from Mr S on NHS, taking 75mg Asprin, Vit D, Pregnacare Plus (w/Omega 3), 5mg Folic Acid (been taking since 1st TOP to try & prevent TS21 or similar issues), NK Cells levels almost double what they should be. 25mg Prednisone from ovulation - CD1 or if BFP then 'til 12 wks and then weaned off 'til 14wks plus Progesterone pessaries from BFP - 16wks, Folic Acid, Omega3, Vit D - 12wks, Asprin - 20wks.
CRYSTAL5 Age 38 - DS age 4. 6 m/c 1 at 11 weeks, 5 at 5/6 weeks. Ok blood tests, under Endocrinologist for Hypothyroid
LADYBEE 37, MC1 (5wks), DS (2), MC2 blighted ovum discovered @ 8 wk scan, MC3 natural @ 9 wks following hb seen at 7 1/2 wk. PCOS previously diagnosed, Factor V Leiden heterozygote discovered in recent testing. Treatment with aspirin (from BFP) + clexane started at 6 weeks. MC4 MMC @ 8.1 wks (discovered @ 11 wk scan) following hb seen at 6+6 wks. Consultant suggests aspirin + clexane to start at 4 weeks, plus progesterone pessaries. Management of MC tbc.
DIGITALGIRL Age 32 - DS 2.8 - 4MCs since ttc#2. MC1 Nov2009 @5wks. MC2 Apr2010 @6-7wks. MC3 Oct2010 @7-8wks. MC4 Mar2011 @8wks. All natural, except MC4 managed with ERPC for karyotyping. Clotting tests normal. DH & I genetically normal. On Metformin for mild PCOS, plus 75mg aspirin, Pregnacare Plus & 25mcg VitD3. Diagnosed with high NK Cells (1.25) after MC4. Starting TTC in May with prednisolone from ovulation and will add cyclogest once pg. Under care of Mr S.
PUREEQUEEN Age 34, MC1 (7 weeks Jan 08) MC2 (6 weeks March 08), DS born (prem) 2009, MC3 (9 weeks Oct 10). MC4 Jan 2011. First 2 natural mcs latter 2 mmc/ERPCs. Chromosome test MC4 showed she had a genetic abnormality (cri du chat). Karotyping for me and DH fine but with "increase in length on satellite of short arm 13 and 15" (??) . Also have endo &septate uterus. Now TTC and will take aspirin and progesterone.
LAF77 , Age 33, MC1 (7 weeks Apr 10) MC2 (5 weeks Sept 10) MC3 (9 weeks Dec 10). All have been natural mcs and number 1 and 3 were embryonic . No children, First appointment with St. Mary's in April, second round of bloods in May, with results in June.

PREGNANT
MATTSMAMA Aged 41. 1st MMC November 2004. My DS (who I love with all my heart) born 2006. 2nd MMC July 2010. 2 chemical pregnancies September and October 2010. Under Dr Shehata and got BFP on first round of treatment for high thyroid antibodies and high killer cells.
BANANA87 Age 30- 1mmc@7 weeks, DD (2), 1 mmc 6 weeks, 1 mc 7 weeks, Going to try aspirin and progesterone as per consultant. Clotting bloods normal.
MUMMYABROAD Age 36, 1DS (2.9), 1MMC Mar 2010 (@14weeks) Ashermans diagnosis and treatment Nov 2010, Started TTC Jan 2011 BFP on Cycle 2 EDD 4/11/11. Heartbeat seen at 10 weeks.
GLITTERYBITS 1 anembryonic MC (12 weeks), unexplained infertility, 1 round of clomid, currently pg and terrified!
JUSTMEE Age 21, MC1 (7 weeks), MC2 (6weeks), MC3 (5weeks) currently pregnant with 4th pregnancy using clexane injecting 20mg a day
LOVELYBUNCHOFCOCONUTS Age 23, 1 MC (13 weeks), 1 MMC (10 weeks - growth stopped at 7), 1DD born 2008, PCOS diagnosis, bi-cornuate uterus. EDD 03/10/11
LOVEMYSLEEP Age 39, 1 mmc, dd born(now 5), 2nd mc (9wks, 2days), 3rd mc (9wks, 3days) and 4th mc at 5 wks. All tests on NHS came back clear. Currently undergoing treatment with Dr.Shehata for very high natural killer cells - aspirin, progesterone, steroids, omezaprole and one intralipid infusion completed.

GRADUATES WITH BABIES!!
LUNATIC dd1(4) 2 mmc (8 wks) dd2 stillborn (32+5). Seen at St Mary's. clotting problem, pg #5 aspirin 150g daily. Ds1 born 9/2/11 c/s @ 35 wks
STILLFRAZZLED Age 35, DS1 (3.6yo), 1 mc @ 5 weeks Jan 09, 2nd mc @ 9 weeks March 09, DS2 born @ 35+3 on 04/01/11 with Intra Uterine Growth Restriction but currently home and doing well.
MUMATRON Age 28 2 dc then 4mc, 3 @9weeks 1@5weeks, tests showed possible free protein s ishoo. dd2 born 06/01/2011, aspirin, claxane and high dose folic acid through pg.
JULEZBOO Age 29 1 mc @ 14 wks, DS1 (8yo) 4 mc @ 5/6 wks, DS2 (3) 2 mc @7 wks... DS3 (14/01/11 @35 wks) Dx with Factor V Leiden and Septate Uterus. Clexane and Aspirin throughout pregnancy and progesterone with DS3.

Thank you for that, you are very reassuring!
Perhaps fortunately we are staying with relatives tonight so I'm away from the machine.

I can be reassuring but believe me, when I was in your shoes I was a complete wreck so I know how you feel! :)

Must be amazing to hear that little beat, I can't imagine what the stress is like when it moves, I stress enough waiting for my 7 weeks scan to come around:)

Wondered if you ladies could help me with something? I'm due af on Thursday and started feeling nauseaus, hot, disturbed sleep (Sat,Sunday,toady) and spotting very small amount light brown (today) i'm about 12dpo. What do you think?

By 12 dpo I would usually be on my third day of testing! I would bring out the trusty first response if I were you
I made dh take the doppler to work with him btw, to prevent any more 'experimenting'.

@ iggi i too poas at 10dpo!!

Well my spotting is getting heavier now still brown sorry if tmi! Seems the witch is on its way, after re-checking im due todayatleast im getting more regular!

Oh well little disapointed but at least Im seeing my consultant next

Hope everything having a good day

jules you still could be pg if the spotting is brown, but only time or clear blue will tell. I've never had spotting during my pgs, but other women do have them. Good luck for your appt next week.

iggi I hope we haven't encouraged you to get a doppler to scare yourself with! It isn't easy in the early days (relatively speaking) to find the HB. I wasn't really sure what I was listening for until the MW visit. The consultant couldn't find it when I went at 14 weeks! It does help to have a full bladder and look quite low down with plenty of gel. It may take some time, but when you find it, it is a little miracle. Hope you are OK.

Hi hope everyones ok and having a good day.

Well af came right on schedule my cycles back to 28 days now after last mc!

Off to see my consultant tomorrow absolutley bricking it if i'm honest! Feels so mad to me, that i'm going through all this being so young (but i'm learning i'm not on my own and my situation could be a lot worse)

Think i'm frightened really of taking that next step, even though I know it needs to be done!

How did your appointment go jules?

Thanks for asking farfallarocks.

Now being seen by a fertility specialist after being stroppy and bursting into tears, she kept reverting back to my mmc at 11 weeks last year (I had a d n c) she asked me why!

They're going to send me for a hysteroscopy and scan (I've never had one when I've not been pregnant) she mentioned I could have scaring that's causing me pain and heavy periods. Or fibroids but wont know till they look!

Feeling much more positive glad someone finally listening:-)

Anybody found this helped or helped get a diagnosis?

That is great news jules I hope you get some answers!

Are they doing any blood tests?

iggi I just noticed your post on the pred thread, is everything ok with you?
Keeping everything crossed for you

Hi all , hope your all keeping ok

No more bloods for now waiting for hysteroscopy on wait list should have in the next 6 weeks.

Had my scan yesterday I've got quite a large fibroid that's probably been causing painful, heavy af's.

When they do hysteroscopy they'll see exactly where it's sitauted i.e womb wall and then decide to remove or leave it be!

Farfall thank you for asking - my midwife heard the heartbeat on Wednesday and there has been no more bleeding since Sunday so (tentatively) hoping I'm in the clear for now.

iggi I'm sorry to read that you had a scare. I hope that you are able to relax a little now that the bleeding stopped and you heard the heartbeat. Will they scan you to see if they can identify the cause of the bleed?

Thinking of you.

Aww iggi send you a big hug.

Fingers crossed all will be fine x

Phew iggi, that must be a big relief

jules good luck with everything

Thanks farfallarocks keeping my fingers crossed for a better year next year!

Merry Christmas everyone

Hello ladies, I hope you don't mind but I've popped in for some advice. I am 36 and I have a DS aged 3.6 (took 6 months to conceive, straightforward pregnancy) I have been trying for DC2 for 2.6 years and in that time I've had 2 early miscarriages (at 7ish weeks), an ectopic (where I lost my left tube) and this week I have had a chemical pregnancy. I am being investigated for RMC by a gynae consultant at my local hospital, I've had several blood tests but I don't have the results appt until Feb, however I work at the same hospital and I have been able to access most of the results (apart from the chromosome tests) and they all seem to be within normal range

The only thing I haven't been tested for is NK cells and the more I read about them the more I think that could be my problem. From my research on Mumsnet it seems that Mr Shetata is the man to see and I was wondering whether I could see him on the NHS, and if so how would I go about it and how long would I have to wait? Also does anyone know the costs/waiting time to see him privately? Thanks in advance ladies!

Hi Greenolives, sorry for your losses.
I know there are people who see Mr Shehata on the NHS, not sure if you have to be local to him or not - worth asking your GP? I know I couldn't see him on NHS and had to go private. I waited a few weeks for the appointment, it is so much faster. The appt was (roughly) 250 and the nkc test 250 iirc - if you can show results for the regular tests he won't repeat them, doing all the tests would cost a lot more. I've had 4 mc after my ds, and am currently 18 weeks pg - still a way to go but my most positive pg yet.
Good luck!

Hi Greenolives, sorry for your losses.
I know there are people who see Mr Shehata on the NHS, not sure if you have to be local to him or not - worth asking your GP? I know I couldn't see him on NHS and had to go private. I waited a few weeks for the appointment, it is so much faster. The appt was (roughly) 250 and the nkc test 250 iirc - if you can show results for the regular tests he won't repeat them, doing all the tests would cost a lot more. I've had 4 mc after my ds, and am currently 18 weeks pg - still a way to go but my most positive pg yet.
Good luck!

Morning, thanks for the info iggi and massive congratulations on your pregnancy So roughly £500 ish for consultation and NK cell tests, that's not as bad as I thought. Do you mind me asking how much your ongoing treatment/care during pregnancy is costing? I need to know how much saving I need to do if we do decide to go private!

Ok let me think. Follow up consultations are a bit cheaper (150 I think). Meds (depends on what you get) cost me 80 for 4 months supply (some people's GPs will take on prescribing for you, mine wouldn't) and once pg you need a couple of scans which are dear at about 200 a piece.
A lot depends on how long it takes to get pg I suppose. If you could try for an nhs referral and start of privately you could switch over. I didn't save I'm afraid, time being of the essence at my age, it's all on a zero percent credit card!

Thanks again iggi, I'm going to have a chat with my consultant when I see him in February and decide what to do then - 0% credit card sounds like a good option! After the heartache of recurrent miscarriages then it seems a relatively small price to pay for the chance of a successful pregnancy. Wishing you a very healthy next 22 weeks and a short and painless labour