mums tried Sertraline and then switched to Venlafaxine (75 now 150mg). Initial boost, but then dip again.
Consultant has suggested rather than increase Venlafaxine to its near maximum - lets add 15mg of Mirtazapine.
even the Doctor used the word "blockbuster" combination. and googling it states "Californian rocket fuel"... Goodness me, what is this going to do to my 65 year old mum?