Anyone tried old style tricyclic meds?

[Sunnyscot80]

Hi all,

After a very long battle with postnatal depression which manifests as severe anxiety, including derealization, nocturnal panic attacks, nightmare, insomnia and horrific morning anxiety, my psych has now recommended I try a tricyclic med.

Ive tried pretty much all the ssri's (setraline, mirtazapine and lexapro) which just make the aggitation worse, or make me very sick. I also tried venlafaxine which was OK but I felt off my face (in an illegal drug kind of way!).

I'm desperate and feel theres not much left for me. I hate this anxiety. And the nocturnal panic attacks / waves of adrenaline are just the worst.

I was wondering if anyone has had similar symptoms and had any luck with tricyclics? I'd maybe try venlafaxine again (reluctantly) to see if the 'off my chops' feeling passed.

There was also talk of valdoxan but its hard to get here in Scotland on the NHS. Any advice appreciated 🙏❤️

@Notanotherwindow

Don't piss about with the dose. The coating is gastro-resistant, it's designed to break down slowly for controlled release. If you cut it, you get too much too quickly and then a period without enough. Take it as instructed.

I also wouldn't keep stop starting things. Again, you are upsetting the chemical balance in your brain by keep changing things.

You're only going to make the adjustment period worse and longer by messing about with it. Its one of those things where you have to either commit to trying something and give it a chance, or not.

Just wanted to say I didn't suggest pissing about with the dose,I suggested asking the psychiatrist if this was possible.

OP,really hope the new meds help🤞

@MrsPelligrinoPetrichor thank you lovely x

For my elder sister, a combination of a tricyclic and an ssri worked.