Have been taking my antidepressants (venlofaxine) for PND. Have been on them for bout 5 months now and have started having the odd glass of wine which has turned into the odd bottle of wine. Does anyone know if the alchol stops the antideps from working properly as have been feeling quite desolate again. Or maybe someone else has experienced mixing the two. Will go to the doctors at some point but just thought I would post on MN for any others experiences.