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Share your dilemmas and get honest opinions from other Mumsnetters.

What do we REALLY think about the weight loss jabs?

782 replies

Newbabynewhouse · 20/09/2026 21:52

I've put this on AIBU rather than weight loss jab because I want a neutral audience rather than people who are all using the jab.
What are peoples thoughts on the jab? I'd love to hear from someone educated in the medical field about whether these are actually safe for people without diabetes.
I'm obese and I have lost a stone so far by dieting although it's taking me a long time! I know if I keep trying hard I can lose what I need to. Lots of people I know have started dropping weight from using the jabs and I am tempted however, can't shake a feeling that there's something not quite right.
What I mean by this is... these jabs have been around for years for diabetic people, so why have they only just been 'released' to people despite obesity effecting the NHS for years?
I know a woman who fainted in work the other day with gallbladder issues, she's on the jab.
Also, I'm going to sound a little conspiracy theorist now, but, isn't it odd these jabs became popular straight after people starting refusing to have more covid jabs..?.. I'd love to hear from people with a bit of background info or medical professionals to tell me whether I'm overthinking or if I'm onto something?

OP posts:
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ChunkyMonkey36 · 22/09/2026 15:19

Stormyrose · 22/09/2026 15:16

No it means little, it just means she was on the meds basically. And they won’t have helped. My own doctor told me about that nurse, she was very unwell and the drugs were irrelevant, she would have died anyway.

what happened was her family linked them, and went to the media and it went viral , it was listed as a contributing factor, as the cost and time to do a huge investigation to prove it wasn’t the drugs was not seen as necessary as the medical staff knew why she died and the cause of death was clearly listed. She had acute pancreatitis, which was not as she’d taken a second low level injection of mounjaro

acute pancreatitis is quite common, about 50 people in every 100k, it’s not a new thing or anything.

Sorry, hadn’t seen this when I posted above.

Thanks. My concern was that it was a genuine contributory link, and after 2 doses that’s not something to be dismissed.

Chickpeacurrywithrice · 22/09/2026 15:22

mulberrymilk · 22/09/2026 14:32

What are you talking about. The poster wanted me to demonstrate someone who had died after using GLP1s, when wanting to lose weight before a wedding. The end.

I don't have a postition. HTH.

But if it makes you feel happy, there have been no deaths associated with GLP1s used by either diabetics or for weight loss, and there have not been 100s of thousands of reports of adverse effects in the UK alone. There, enjoy your delusions. Most sane people prefer to be well informed on any adverse long term effects of any drug they might be on. YMM clearly varies.

lots of people will have died after using WLI, that woman did, but it wasn’t linked! They’ll die from heart attacks, cancer, gastrointestinal issues, but at is clearly documented on the death certificate, it wasn’t linked, it’s just Roy (with £££££s in his eyes) deciding he has some sort of medical knowledge!

SilenceInside · 22/09/2026 15:28

@wldpwr there will likely be an “uptick” in gallbladder issues as it’s associated with losing weight. GLP1s mean people lose weight. There’s no evidence that taking a GLP1 increases your risk of developing gallbladder issues above and beyond any other risk factors that apply to you. With several million people successfully losing weight on GLP1s I’d be amazed if there was no increase in gall bladder issues at all. Overall it is still better for your health to lose weight, even if you end up having your gall bladder out as a result. Better than remaining obese, and still being at higher risk of gallbladder issues.

peppy23 · 22/09/2026 15:34

ChunkyMonkey36 · 22/09/2026 15:16

The gov info says:

Part 2
You should also enter any other diseases, injuries, conditions or events that contributed to the death, but were not part of the direct sequence, in part 2 of the MCCD. The conditions mentioned in part 2 must be known or suspected to have contributed to the death, not merely be other conditions which were present at the time.

I would say that 2 doses of WLI being either known or suspected to have contributed to death, rather than just that they were known to have been taken, is a concern.

You might, but that doesn’t mean the NHS/MHRA agrees and I’d be be inclined to listen to those who are in those organisations.

peppy23 · 22/09/2026 15:35

Sorry that sounded snippy @ChunkyMonkey36it wasn’t intended that way. Everyone has their own risk tolerances, good thing is no one is being forced to take any sort of medication.

the issue I have is when people (not you) misinterpret information and use it to scaremonger.

Stormyrose · 22/09/2026 15:39

peppy23 · 22/09/2026 15:35

Sorry that sounded snippy @ChunkyMonkey36it wasn’t intended that way. Everyone has their own risk tolerances, good thing is no one is being forced to take any sort of medication.

the issue I have is when people (not you) misinterpret information and use it to scaremonger.

That’s how I feel, if a contributing factor is a concern then don’t take them but if I remember correctly the poster doesn’t want to anyway, so no big deal. Everyone has their own risk factors. For me this isn’t remotely a concern. Especially with the new study showing no increase in risk of pancreatitis, and my own gp knowing the details behind this.

wldpwr · 22/09/2026 15:41

SilenceInside · 22/09/2026 15:28

@wldpwr there will likely be an “uptick” in gallbladder issues as it’s associated with losing weight. GLP1s mean people lose weight. There’s no evidence that taking a GLP1 increases your risk of developing gallbladder issues above and beyond any other risk factors that apply to you. With several million people successfully losing weight on GLP1s I’d be amazed if there was no increase in gall bladder issues at all. Overall it is still better for your health to lose weight, even if you end up having your gall bladder out as a result. Better than remaining obese, and still being at higher risk of gallbladder issues.

I completely agree...

... and I also suspect over time there will be a proven association between GLP 1 and gallbladder complications based on what the doctors have said.

Allisnotlost1 · 22/09/2026 15:51

Stormyrose · 22/09/2026 13:58

I recognise your writing style from other threads on this subject and your insistence on face to face reviews and the whole prevent obesity and it’s been pointed out to you many many times, I don’t beleive you are surprised, I beleive it ruins your argument so you don’t wish to accept it.

I don’t think I’ve ever posted on WLIs, only saw this thread because it came up on the list below another. I (mistakenly) thought it was an interesting subject.

I haven’t insisted on face to face reviews, at all. And I couldn’t care less what you believe.

Allisnotlost1 · 22/09/2026 15:57

Stormyrose · 22/09/2026 14:42

Nope, she also didn’t die due to the drugs, she was very unwell in the first place. The drug didn’t directly cause her death, sadly she would have died anyway, they are listed as a contributing factor, but she would have died sadly anyway,

honestly just stop you’re embarassing yourself now and coming across as desperate..

A contributing factor on a death certificate is a medical condition or disease that played a role in the death, but did not directly cause the final chain of events that led to it.

You can argue that the drugs didn’t cause her death but it’s plainly wrong to pretend they were irrelevant. If they were they wouldn’t be listed.

You keep describing others as desperate but you sound like someone petrified that the small amount of evidence of harm will somehow threaten your supply. You’re incapable
of accepting any different viewpoint or idea without flying off the handle.

ChunkyMonkey36 · 22/09/2026 16:02

@peppy23 / @Stormyrose

No you’re quite right, I don’t take them. Not because of the risk factors, but because I don’t personally see the cost vs benefit as enough for me.

I don’t, for example, believe there’s a gall bladder risk that doesn’t exist with other factors. It might be that WLI increase your risk of gall bladder issues. But that’s not likely because of the injection themselves, but because that’s an associated risk of losing weight, which is what they’re used for.

I had gallstones already at my last scan, they just weren’t bothering me. If they start bothering me now because I’ve lost weight, they’d have done that with or without WLI.

I commented on the deaths and whether they were associated or not is because whether you’re taking them personally or not, if they were increasing risk of death that’s obviously a concern. I know plenty on them, I’d rather they didn’t have a death contributed to by them. That’s not an unreasonable concern.

However now you’ve explained the context, I have already acknowledged that.

ExtraOnions · 22/09/2026 16:05

I have Gallstones, used to have a terrible attack every couple of months.

I’ve not had one since I started on the WLIs ..

I’ve lost 5 stone, I sm on a lower dose now as still have weight to lose.

The knee surgery I was getting scheduled for is no longer needed.

I am at a lower risk for Heart Attack and Stroke.

Chickpeacurrywithrice · 22/09/2026 16:08

ExtraOnions · 22/09/2026 16:05

I have Gallstones, used to have a terrible attack every couple of months.

I’ve not had one since I started on the WLIs ..

I’ve lost 5 stone, I sm on a lower dose now as still have weight to lose.

The knee surgery I was getting scheduled for is no longer needed.

I am at a lower risk for Heart Attack and Stroke.

And many cancers

SilenceInside · 22/09/2026 16:22

@wldpwr I think that with real world data in the millions across the world it will be the case that the risk of gallbladder complications will prove to be no higher than the risk of gallbladder complications from losing weight on its own. There should be a lot of data available and I’m sure someone somewhere is crunching the numbers.

WLIcurious · 22/09/2026 16:28

Going back to the original post, it does look like for some people, WLI scaremongering and misinformation is taking the place of the covid jab conspiracies. Back then, every time someone got ill or died it was attributed to the covid jabs. Didn’t matter if they’d fallen off a cliff or had terminal cancer, it was definitely the jab wot done ‘em in.

Allisnotlost1 · 22/09/2026 16:28

SilenceInside · 22/09/2026 15:28

@wldpwr there will likely be an “uptick” in gallbladder issues as it’s associated with losing weight. GLP1s mean people lose weight. There’s no evidence that taking a GLP1 increases your risk of developing gallbladder issues above and beyond any other risk factors that apply to you. With several million people successfully losing weight on GLP1s I’d be amazed if there was no increase in gall bladder issues at all. Overall it is still better for your health to lose weight, even if you end up having your gall bladder out as a result. Better than remaining obese, and still being at higher risk of gallbladder issues.

Agree but it’s associated with rapid weight loss of any kind, not weight loss per se, so it’s the speed which is the issue. Of course that same risk applies to crash diets, gastric bands etc.

Stormyrose · 22/09/2026 16:29

ExtraOnions · 22/09/2026 16:05

I have Gallstones, used to have a terrible attack every couple of months.

I’ve not had one since I started on the WLIs ..

I’ve lost 5 stone, I sm on a lower dose now as still have weight to lose.

The knee surgery I was getting scheduled for is no longer needed.

I am at a lower risk for Heart Attack and Stroke.

Weight gain and loss leads to gall stones. I don’t see anyone posting about fat people having an increased risk.

the bottom line is everyone has different risk assesments, for me the proven and very real risks of obesity related illnesses or death is much higher than a small unproven risk associated with these meds, but that’s my risk factor assessment,

same with nurofen, 2000 people die each year on average from taking it in recommended dosage. I’ve yet to see any threads on it. And that’s over the counter.

either way as said, the drugs aren’t going away, they will only be more widespread, obesity rates will thankfully reverse and the population become healthier, we will see less heart attack,strokes, diabetes, cancers, and less joint replacements required, amongst many other things, and if some don’t want to take it as they are scared and feel there is a bigger risk to their health, that’s also all good, it’s personal choice. If they have weighr problems I hope they get to a healthy weight and can maintain it, thr latter being the most difficult part. But I wish them well on their journeys and I hope they succeed before they feel the impacts of their weight and that they feel happy when as they go on their journey, as mental health is also important.

what those people can’t do, is dictate no one else can have them, or how they access them, their opinion carries no weight other than what they themselves do for their own health,

lovethepuppies · 22/09/2026 16:39

I started them a 2.5 years ago, as soon as they came out . Was very nervous, but I never had any side effects ( apart from weight loss )
I lost 12.5 stone and so far have managed to keep it off. It’s literally helped me save my life

MeetMeOnTheCorner · 22/09/2026 16:44

@ChunkyMonkey36Depends if there’s a greater risk of death and other serious health problems by not losing weight though. Nearly every decision has a risk but the risks associated with being overweight are well known. So I’d rather be lighter and I’m more than happy with my jabs. My only “regret” is my beautiful clothes at size 18 are now falling off me! I’m very delighted to be a size 14 again but it’s expensive buying new clothes! Fun, but pricey.

MoneyJo · 22/09/2026 17:20

mulberrymilk · 22/09/2026 07:52

Are you still upset I quoted this and mentioned it was ironic?

However when it is discussed with a lot of misinformation, people are bound to come in with some facts.

This thread is full, if you actually read it, of people on WLI who are posting incorrect "facts," incorrectly correcting correct facts, refusing to accept the actualities, for example, arguing until they are blue in the face that gallbladder disease is not in any way related to WLI beyond the losing weight fast bit, or that pancreatitis is in any way related to using WLI. These are established facts.

Edited

Nope. I didn't appreciate your rudeness though, and clearly I wasn't the only one as it seems some of your posts were reported and deleted.

Allisnotlost1 · 22/09/2026 18:02

Stormyrose · 22/09/2026 16:29

Weight gain and loss leads to gall stones. I don’t see anyone posting about fat people having an increased risk.

the bottom line is everyone has different risk assesments, for me the proven and very real risks of obesity related illnesses or death is much higher than a small unproven risk associated with these meds, but that’s my risk factor assessment,

same with nurofen, 2000 people die each year on average from taking it in recommended dosage. I’ve yet to see any threads on it. And that’s over the counter.

either way as said, the drugs aren’t going away, they will only be more widespread, obesity rates will thankfully reverse and the population become healthier, we will see less heart attack,strokes, diabetes, cancers, and less joint replacements required, amongst many other things, and if some don’t want to take it as they are scared and feel there is a bigger risk to their health, that’s also all good, it’s personal choice. If they have weighr problems I hope they get to a healthy weight and can maintain it, thr latter being the most difficult part. But I wish them well on their journeys and I hope they succeed before they feel the impacts of their weight and that they feel happy when as they go on their journey, as mental health is also important.

what those people can’t do, is dictate no one else can have them, or how they access them, their opinion carries no weight other than what they themselves do for their own health,

You are shockingly ill informed for someone so opinionated. Obesity is a major risk factor for gallstones, and gallbladder dysfunction for women.

https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/gallstones/

https://www.doctorbotvinov.com/blog/the-link-between-obesity-and-gallbladder-issues

Stormyrose · 22/09/2026 18:09

Allisnotlost1 · 22/09/2026 18:02

You are shockingly ill informed for someone so opinionated. Obesity is a major risk factor for gallstones, and gallbladder dysfunction for women.

https://www.nhsinform.scot/illnesses-and-conditions/stomach-liver-and-gastrointestinal-tract/gallstones/

https://www.doctorbotvinov.com/blog/the-link-between-obesity-and-gallbladder-issues

Did you quote the wrong person, as you literally agreed with me. Or did you want to attack so badly you didn’t read properly?

Allisnotlost1 · 22/09/2026 18:15

Stormyrose · 22/09/2026 18:09

Did you quote the wrong person, as you literally agreed with me. Or did you want to attack so badly you didn’t read properly?

Obesity means an increased risk of gallstones, weight loss is actually not mentioned. I also thought rapid loss was the main issue but I went off and read up on it.

wldpwr · 22/09/2026 18:18

SilenceInside · 22/09/2026 16:22

@wldpwr I think that with real world data in the millions across the world it will be the case that the risk of gallbladder complications will prove to be no higher than the risk of gallbladder complications from losing weight on its own. There should be a lot of data available and I’m sure someone somewhere is crunching the numbers.

Sure, although I haven't reported my gallbladder issues to Eli Lilly (and they might well say "how do you know you didn't have them anyway?").

I bet many people are the same.

Pelotonia · 22/09/2026 18:19

OonaStubbs · 20/09/2026 23:32

I don't like them at all.

It's not fair on people who have lost weight through use of exercise and willpower. Some people will still be eschewing the use of these drugs and doing it the old fashioned way, yet people will think they are cheating by shooting up drugs. To me it is no different to sports people taking performance enhancing drugs.

Seriously??? I lost 5 stone ‘naturally’ a few years ago. How on earth am I adversely affected by someone else losing weight in a different way?

SilenceInside · 22/09/2026 18:26

@wldpwr I don’t think people would need to individually report gallbladder issues to the manufacturer. The kind of data analysis I had in mind would be done on data held by the NHS or the equivalent in other countries. For example my NHS record shows my private Mounjaro prescription and would also record any treatment I had for gallbladder issues.