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What do we REALLY think about the weight loss jabs?

782 replies

Newbabynewhouse · 20/09/2026 21:52

I've put this on AIBU rather than weight loss jab because I want a neutral audience rather than people who are all using the jab.
What are peoples thoughts on the jab? I'd love to hear from someone educated in the medical field about whether these are actually safe for people without diabetes.
I'm obese and I have lost a stone so far by dieting although it's taking me a long time! I know if I keep trying hard I can lose what I need to. Lots of people I know have started dropping weight from using the jabs and I am tempted however, can't shake a feeling that there's something not quite right.
What I mean by this is... these jabs have been around for years for diabetic people, so why have they only just been 'released' to people despite obesity effecting the NHS for years?
I know a woman who fainted in work the other day with gallbladder issues, she's on the jab.
Also, I'm going to sound a little conspiracy theorist now, but, isn't it odd these jabs became popular straight after people starting refusing to have more covid jabs..?.. I'd love to hear from people with a bit of background info or medical professionals to tell me whether I'm overthinking or if I'm onto something?

OP posts:
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6
Stormyrose · 22/09/2026 10:29

Cucurella · 22/09/2026 09:46

Yes, in my case HRT. I request repeat prescriptions from my GP and send them blood pressure readings which I take myself. I haven’t seen the GP in years but my Mounjaro provider sends them details of every prescription and my surgery contacted me to give me advice on adjusting my HRT dose when using Mounjaro.

I’ve also bought pharmacy medicines online from Boots and other providers by filling in forms on my condition and other medications I’m taking.

Self reporting and management is the way forward for many conditions and it works. I don’t need to see a GP for HRT or Mounjaro. I can manage it myself, freeing up doctor’s appointments for those who need it more.

Same for my blood pressure meds when I was on them and my husband with his statins and presciption only anti histamines, and he sees the asthma nurse once a year.

the population is a lot more intelligent than posters are giving them credit for. And for weight loss meds if you wish to see a private doctor, you can. It’s a widely available service, and every pharmacy has a prescriber available to discuss, and many of them offer a mid service where you can have video calls etc, and it doesn’t cost more.

but I strongly suspect the small handful of posters know this, there is clearly something else behind their extreme concern about obese people. I’d also suspect they aren’t arguing about any other prescription only meds, just the ones where women can lose weight and look fab.

Gettingbysomehow · 22/09/2026 10:30

mulberrymilk · 22/09/2026 08:35

"...no one has to take them, but for the millions and millions who do wish to, it’s nothing short of wonderful.”

I would think for those poor souls who died taking them - just hoping to lose a dress size or shirt size or two before a wedding, etc. - it is a fair bit short of wonderful.

Edited

I'm sorry but you don't get prescribed GLP-1s so you can lose a dress size for a wedding. They have very strict criteria and you have to provide proof that you are obese. Even if you buy them privately. Then you have to provide photos of yourself in very skimpy clothing.
You have to be on the obese scale to get them.
I was 15 stone and had diabetes, massively high blood pressure and joint problems. Mine were not available on the NHS so I paid for them.
I am now 9 stone, no diabetes, no high blood pressure and I don't need the knee replacement. I took charge of my own health.
You have to send a lot of medical information in.
They emailed my GP to check. Twice actually. It took two years to lose weight not five minutes.
You can only get GLP-1s to lose a dress size if you get them on the black market and who knows what is in it. Several people have died from black market injections.

Allisnotlost1 · 22/09/2026 11:55

Cucurella · 22/09/2026 09:46

Yes, in my case HRT. I request repeat prescriptions from my GP and send them blood pressure readings which I take myself. I haven’t seen the GP in years but my Mounjaro provider sends them details of every prescription and my surgery contacted me to give me advice on adjusting my HRT dose when using Mounjaro.

I’ve also bought pharmacy medicines online from Boots and other providers by filling in forms on my condition and other medications I’m taking.

Self reporting and management is the way forward for many conditions and it works. I don’t need to see a GP for HRT or Mounjaro. I can manage it myself, freeing up doctor’s appointments for those who need it more.

Interesting, thanks. This wasn’t my experience, and I’m glad to have had periodic in person reviews of HRT and all the meds I’ve had to take because of the potential for side effects. I can request repeats but have to see or speak to the GP every year and have annual
blood tests/check ups.

AWomanOfWealthAndTaste · 22/09/2026 12:48

Stormyrose · 22/09/2026 10:29

Same for my blood pressure meds when I was on them and my husband with his statins and presciption only anti histamines, and he sees the asthma nurse once a year.

the population is a lot more intelligent than posters are giving them credit for. And for weight loss meds if you wish to see a private doctor, you can. It’s a widely available service, and every pharmacy has a prescriber available to discuss, and many of them offer a mid service where you can have video calls etc, and it doesn’t cost more.

but I strongly suspect the small handful of posters know this, there is clearly something else behind their extreme concern about obese people. I’d also suspect they aren’t arguing about any other prescription only meds, just the ones where women can lose weight and look fab.

I may be wrong, but I've often had the impression that the people insisting there needs to be more scrutiny and face to face genuinely are surprised to learn how common it is to rely on remote consultations and self-reporting. Possible I'm misreading them.

What I do know is they never come back and explain either why private WLI prescriptions need more scrutiny than so many other conditions and drugs, and where the HCPs are going to come from.

mulberrymilk · 22/09/2026 13:25

Gettingbysomehow · 22/09/2026 10:30

I'm sorry but you don't get prescribed GLP-1s so you can lose a dress size for a wedding. They have very strict criteria and you have to provide proof that you are obese. Even if you buy them privately. Then you have to provide photos of yourself in very skimpy clothing.
You have to be on the obese scale to get them.
I was 15 stone and had diabetes, massively high blood pressure and joint problems. Mine were not available on the NHS so I paid for them.
I am now 9 stone, no diabetes, no high blood pressure and I don't need the knee replacement. I took charge of my own health.
You have to send a lot of medical information in.
They emailed my GP to check. Twice actually. It took two years to lose weight not five minutes.
You can only get GLP-1s to lose a dress size if you get them on the black market and who knows what is in it. Several people have died from black market injections.

There is a whole wide world out there. That is what has been reported, by the partners of these deceased people. Maybe they needed to lose a lot more weight than that, objectively speaking, but they died anyway.

mulberrymilk · 22/09/2026 13:35

Stormyrose · 21/09/2026 13:35

Sigh. Nope that was early trial data, recent wide clinical review shows no increased risk, you can google there is many studies and reviews.

https://pubmed.ncbi.nlm.nih.gov/40358430/

https://www.ccjm.org/content/92/8/483

https://www.medrxiv.org/content/10.64898/2026.03.19.26348844v1.full

Here you go. Perhaps they have got it all wrong, along with the BMJ.

"The product information for all Glucagon-Like Peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists (dulaglutide, exenatide, liraglutide, semaglutide and tirzepatide) has been further updated to highlight the potential risk of severe acute pancreatitis with these products, including rare reports of necrotising and fatal pancreatitis. Healthcare professionals should remain vigilant for signs and symptoms of acute pancreatitis in patients treated with GLP-1 and GLP-1/GIP receptor agonists."

GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases - GOV.UK

GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases

The product information for all Glucagon-Like Peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists has been further updated to highlight the potential risk of severe acute pancreatitis...

https://www.gov.uk/drug-safety-update/glp-1-receptor-agonists-and-dual-glp-1-slash-gip-receptor-agonists-strengthened-warnings-on-acute-pancreatitis-including-necrotising-and-fatal-cases

Gettingbysomehow · 22/09/2026 13:50

I cant understand why it is suddenly so dangerous. Diabetics have been using it for 20 years. There was no country wide freaking out about that. Maybe diabetics don't matter. IDK.

peppy23 · 22/09/2026 13:51

mulberrymilk · 22/09/2026 08:35

"...no one has to take them, but for the millions and millions who do wish to, it’s nothing short of wonderful.”

I would think for those poor souls who died taking them - just hoping to lose a dress size or shirt size or two before a wedding, etc. - it is a fair bit short of wonderful.

Edited

Here’s a grip, sounds like you need it.

peppy23 · 22/09/2026 13:52

This reply has been deleted

Message deleted by MNHQ. Here's a link to our Talk Guidelines.

peppy23 · 22/09/2026 13:52

mulberrymilk · 22/09/2026 13:35

Here you go. Perhaps they have got it all wrong, along with the BMJ.

"The product information for all Glucagon-Like Peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists (dulaglutide, exenatide, liraglutide, semaglutide and tirzepatide) has been further updated to highlight the potential risk of severe acute pancreatitis with these products, including rare reports of necrotising and fatal pancreatitis. Healthcare professionals should remain vigilant for signs and symptoms of acute pancreatitis in patients treated with GLP-1 and GLP-1/GIP receptor agonists."

GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases - GOV.UK

POTENTIAL not definitive cause.

Allisnotlost1 · 22/09/2026 13:54

AWomanOfWealthAndTaste · 22/09/2026 12:48

I may be wrong, but I've often had the impression that the people insisting there needs to be more scrutiny and face to face genuinely are surprised to learn how common it is to rely on remote consultations and self-reporting. Possible I'm misreading them.

What I do know is they never come back and explain either why private WLI prescriptions need more scrutiny than so many other conditions and drugs, and where the HCPs are going to come from.

I can’t speak for others but I have been surprised by it, because it hasn’t been my experience of a range of medications, including some of the ones mentioned and some less and more dangerous.

Stormyrose · 22/09/2026 13:56

peppy23 · 22/09/2026 13:52

POTENTIAL not definitive cause.

Not just that the trial data of 740k participants showing no increase in risk was published In April this year, 3 months after the uk gov data, but the poster is refusing to accept new data is out proving the potential risk is not a risk at all.

SilenceInside · 22/09/2026 13:57

@mulberrymilk perhaps I'm missing something about that gov.uk website but it doesn't mention anything about an increased risk of pancreatitis? It just mentions it as a possible but rare side effect and serves to repeat the information to HCP about it being a rare side effect and to make sure patients are informed of the symptoms. Which they should have been anyway.

From the link, the MHRA Yellow Card scheme received 1296 reports of pancreatitis associated with GLP1 usage, with 19 fatalities and 24 reported as necrotising pancreatitis across 2007 to Oct 2025. That's in the context of an estimate of 25.4 million packs of GLP1 medication prescribed. Importantly, the MHRA Yellow Card scheme absolutely does not determine causality, it is an association only, and in each case the cause of the pancreatitis may not be related to GLP1 use at all.

Stormyrose · 22/09/2026 13:58

Allisnotlost1 · 22/09/2026 13:54

I can’t speak for others but I have been surprised by it, because it hasn’t been my experience of a range of medications, including some of the ones mentioned and some less and more dangerous.

I recognise your writing style from other threads on this subject and your insistence on face to face reviews and the whole prevent obesity and it’s been pointed out to you many many times, I don’t beleive you are surprised, I beleive it ruins your argument so you don’t wish to accept it.

mulberrymilk · 22/09/2026 13:59

peppy23 · 22/09/2026 13:52

POTENTIAL not definitive cause.

Potential risk. Yes, that is what the warning is for. You know, acknowledged adverse effects, as put on the product warnings by the manufacturers.

You know, the one the poster I quoted said did not exist.

Nope that was early trial data, recent wide clinical review shows no increased risk

You could read the whole NHS page linked to properly understand what this is about.

peppy23 · 22/09/2026 13:59

mulberrymilk · 22/09/2026 13:59

Potential risk. Yes, that is what the warning is for. You know, acknowledged adverse effects, as put on the product warnings by the manufacturers.

You know, the one the poster I quoted said did not exist.

Nope that was early trial data, recent wide clinical review shows no increased risk

You could read the whole NHS page linked to properly understand what this is about.

Are you this passionate about all medication? Or just the ones that help fat people?

Stormyrose · 22/09/2026 14:00

SilenceInside · 22/09/2026 13:57

@mulberrymilk perhaps I'm missing something about that gov.uk website but it doesn't mention anything about an increased risk of pancreatitis? It just mentions it as a possible but rare side effect and serves to repeat the information to HCP about it being a rare side effect and to make sure patients are informed of the symptoms. Which they should have been anyway.

From the link, the MHRA Yellow Card scheme received 1296 reports of pancreatitis associated with GLP1 usage, with 19 fatalities and 24 reported as necrotising pancreatitis across 2007 to Oct 2025. That's in the context of an estimate of 25.4 million packs of GLP1 medication prescribed. Importantly, the MHRA Yellow Card scheme absolutely does not determine causality, it is an association only, and in each case the cause of the pancreatitis may not be related to GLP1 use at all.

Yes and there is now many studies published showing not only no increase in risk but that the drugs actually reduce the number of pancreatic cancer cases, which can be directly linked to pancreatitis, in mounjaro it’s 69 percent reduction. So you’re safer on them.

but again, let’s use old data and pretend it’s up to date.

Stormyrose · 22/09/2026 14:01

peppy23 · 22/09/2026 13:59

Are you this passionate about all medication? Or just the ones that help fat people?

Fat women to be precise,,

mulberrymilk · 22/09/2026 14:01

peppy23 · 22/09/2026 13:59

Are you this passionate about all medication? Or just the ones that help fat people?

I'm passionate about facts.

People in denial are intensely devoted to ignoring or twisting facts.

mulberrymilk · 22/09/2026 14:03

SilenceInside · 22/09/2026 13:57

@mulberrymilk perhaps I'm missing something about that gov.uk website but it doesn't mention anything about an increased risk of pancreatitis? It just mentions it as a possible but rare side effect and serves to repeat the information to HCP about it being a rare side effect and to make sure patients are informed of the symptoms. Which they should have been anyway.

From the link, the MHRA Yellow Card scheme received 1296 reports of pancreatitis associated with GLP1 usage, with 19 fatalities and 24 reported as necrotising pancreatitis across 2007 to Oct 2025. That's in the context of an estimate of 25.4 million packs of GLP1 medication prescribed. Importantly, the MHRA Yellow Card scheme absolutely does not determine causality, it is an association only, and in each case the cause of the pancreatitis may not be related to GLP1 use at all.

The part I quoted, for starters, which included this line -

The product information for all Glucagon-Like Peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) receptor agonists (dulaglutide, exenatide, liraglutide, semaglutide and tirzepatide) has been further updated to highlight the potential risk of severe acute pancreatitis with these products, including rare reports of necrotising and fatal pancreatitis.

SilenceInside · 22/09/2026 14:04

Regarding self reporting, my NHS GP practice expects me to self measure my BP with an at home BP machine and self report it, to a pharmacist, for my annual review. They don't even ask for any other information or changes, not interested in my current weight despite knowing that I was obese.

Stormyrose · 22/09/2026 14:05

mulberrymilk · 22/09/2026 14:01

I'm passionate about facts.

People in denial are intensely devoted to ignoring or twisting facts.

That doesn’t appear to be the case, your arguments are one sided, don’t look at the meds and why we have rhem holistically and you only want to focus on data that helps your position.

mulberrymilk · 22/09/2026 14:07

WLIcurious · 22/09/2026 09:45

Can you provide evidence that of the people who have died while using WLIs that it was the WLIs that directly caused their death?

Also, how many of those people were confirmed to be taking WLIs only to lose a dress or shirt size before a wedding?

While she didn’t have diabetes, the 56-year-old Australian woman hoped to lose weight in the lead-up to her daughter’s wedding, after diet and exercise proved unsuccessful.

56-Year-Old Woman's Death Linked to Ozempic, Family Claims

Ozempic: Woman dies after using weight loss drugs | Nine.com.au

Trish wanted to lose a few kilos, now she's dead

https://www.nine.com.au/australia-news/60-minutes/ozempic-weight-loss-drug-side-effects-20231105-p5rg66.html

peppy23 · 22/09/2026 14:08

mulberrymilk · 22/09/2026 14:01

I'm passionate about facts.

People in denial are intensely devoted to ignoring or twisting facts.

lol no you’re not! there’s plenty of positive facts associated with WLI and I’ve not seen you mention any?

Every single highly effective medication from common blood pressure pills to basic antibiotics carries a list of rare, severe side effects. Singling out GLP-1s is purely a cultural bias, not a medical one.

These medications lower blood pressure, lower cholesterol, lower cancer risks, and save lives, but you're so blinded by your own fat-shaming bias that you're treating a medical breakthrough like a moral failure!

do better

peppy23 · 22/09/2026 14:10

mulberrymilk · 22/09/2026 14:07

While she didn’t have diabetes, the 56-year-old Australian woman hoped to lose weight in the lead-up to her daughter’s wedding, after diet and exercise proved unsuccessful.

56-Year-Old Woman's Death Linked to Ozempic, Family Claims

Ozempic: Woman dies after using weight loss drugs | Nine.com.au

No where in that article does it state WLI were the cause.

the family think it was. That means sweet FA.

it even says NO DIRECT LINKS HAVE BEEN MADE.

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