I suffered from depression in the past without medication and it was a terrible time.
More recently when depression came, even though it was less crushing, I went on to ADs and have been on for nearly 2 years and feeling mostly fine.
I've never suffered particularly with PMS, apart from slight and short lived mood changes.
I'm mid 40s and have started to notice that mid cycle I am getting terribly low and really hating life, despite the medication, which usually makes me feel pretty normal. Does anyone else have this? Is ovulation related depression a thing in perimenopause? I also have headaches at the same time and around my period. My periods are still normal and regular but this is taking me out of action for a few days each month.