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Back on jabs after weighty hiatus - desperate!

17 replies

Uggcoo · 07/11/2026 10:09

Back on Mounjero after promising myself I wouldn't fail at keeping away from this very expensive option. In a month, my appetite returned with a vengeance ( course it did). So now back to original weight and bad habits despite downloading diet apps , couch25k etc.I am feeling down about it all but LOVED being slim plus can't fit into any of lovely clothes I bought for this period of my life. I took it for 3yrs and am 62. Anyone on here who has had a similar experience ? Am I now on it for life? I work full time (about 60 hours a week ) bumping up private pension because I hope to retire 2yrs time. I keep thinking once I retire I will exercise and plan proper healthy meals..

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OP posts:
WeAllHaveWings · 07/11/2026 11:30

For many it will need to be a life long treatment for the relapsing chronic disease of obesity. Hopefully once patents expire and generics come out it will get cheaper.

I have not come off, I am slowly working out the lowest dose that continues to support me.

I have decreased slowly over the last 10 months and I am currently on 1.67mg (8 weeks) and maintaining so far. It doesn't feel like it is doing much, but I am sure it is and I plan to stick with for at least a year as I cannot risk going back to being morbidly obese.

The small dose, if I can continue to maintain on it and retain the inflammation benefits, makes it very affordable.

LouisFuton · 07/11/2026 11:35

I wonder if maintenance is based on how big you were before starting? Like if you were big for a long time beforehand?

Mackerelfillets · 07/11/2026 11:44

Uggcoo · 07/11/2026 10:09

Back on Mounjero after promising myself I wouldn't fail at keeping away from this very expensive option. In a month, my appetite returned with a vengeance ( course it did). So now back to original weight and bad habits despite downloading diet apps , couch25k etc.I am feeling down about it all but LOVED being slim plus can't fit into any of lovely clothes I bought for this period of my life. I took it for 3yrs and am 62. Anyone on here who has had a similar experience ? Am I now on it for life? I work full time (about 60 hours a week ) bumping up private pension because I hope to retire 2yrs time. I keep thinking once I retire I will exercise and plan proper healthy meals..

.

This is what i'm afraid of. I've lost just over 4st and another 11lbs to go. I have decided i will stick to a maintenance dose long term. I have been jabbing for about the same length of time as you so it has been slow going for me but i love being slimmer. BMI says overweight but im close to where i want to be.

Fedupofthisgame · 07/11/2026 12:02

I'm thinking of coming off it. I got to 10mg having lost 6.5st but I just can't get any lower than 11st 10lb. I'm wasting money and I find for the first 2 days after I've jabbed I am useless. Can't function tired. I don't see what else I can do.

Wildfairy · 07/11/2026 12:04

I’m on it for good or till something better comes along.

im fifty seven and fully aware of my own body. I know i needed the drug to help me get my weight back down, i tried everything and failed before i used mounjaro and i know my body will go back to normal if i come off. Which means i will spend my days hungry, deprived and struggling to maintain my weight.

i chose not to do that and i want the other health benefits of the medication. I pick my physical and mental heath over the struggle.

so staying on a maintenance dose is my choice.

Wildfairy · 07/11/2026 12:07

LouisFuton · 07/11/2026 11:35

I wonder if maintenance is based on how big you were before starting? Like if you were big for a long time beforehand?

I don’t think so, it took me five years all in to gain and lose the weight basically. But I’m post menopause and my body will revert when I come off, the drugs don’t work when you don’t take them, so my blood sugar will no longer be controlled, my inflammation will return, my insulin response will be faulty. All this will result in cravings, hunger and my body converting glucose to fat.

EnterCaroline · 07/11/2026 12:58

I stopped after 19 months due to the price rise; I was 10lb off target. I have put on 20lb of the 70 I lost. It almost bounced on, not so much a gradual creep. I did save hard to afford to try again, but after 3 months saw none of the weight loss benefits. I can't afford it at all now due to a rent increase. I'm hoping that maybe if I can at least maintain where I am and keep saving I could do it again in a year or so, once I have had a long break it may be effective again.

PivotPivotmakingmargaritas · 08/11/2026 17:59

I’m going to be on it for life … I’ve accepted that - I’ve had gastric sleeve and WLI - only WLI have worked in reducing the need for me to seek food for comfort/ dopamine hit. Still there but so much less.

Im 1kg from my goal then I will filter down to- I have a weight bracket I am comfortable being before I start increasing the amount currently 3mg

ThisLemonBee · 08/11/2026 18:20

Everyone, if you are using this medication and want to maintain the results (and long term health) if you’re not already you NEED to be resistance training. Muscle is more metabolically active than fat, the more you have the more you can eat (you will also
also be stronger and look better). If you’ve lost a lot of weight on the jabs and not been lifting weights you have likely lost a lot of muscle too and significantly reduced your metabolism. The app Ladder is brilliant for easy to follow programmes. Not a bad shout to get a few sessions with a coach if unsure on form. Good luck x

YassQweeennn · 08/11/2026 18:53

I don't know a single person that has stayed slim after coming off it. You're on it for life.

FloozyMcGee · 09/11/2026 18:42

your problem is not your will power, your problem is a METABOLIC disorder. Imagine if all of your post had been the same, except instead of fat you were fighting hypothyroidism. "I promised myself I'd never have to take thyroid pills again." It would be ridiculous. Yes, if you want to keep it off, the research is pretty clear: 80% of people will gain back at least 2/3 of their weight. I think of it more as I have to take it to keep myself healthy--I went from failing at high blood pressure meds to now having LOW blood pressure! And my A1C went from being the highest it had ever been to now the lowest. My belly fat is greatly reduced AND I just had my bone density scan and it's far above average. Yeah, I'd LOVE to not have to pay for this, but I'd rather that than die early. Accept it and it will go far easier!

Oxaloacetate · 09/11/2026 20:54

LouisFuton · 07/11/2026 11:35

I wonder if maintenance is based on how big you were before starting? Like if you were big for a long time beforehand?

Every Single method of weight loss shows a U shaped curve over time. Whether that’s diet and exercise, drugs or even bariatric surgery some weight gain always reoccurs. It’s important to remember that the body benefits even from a few months or years at a healthier weight.

Oxaloacetate · 09/11/2026 20:57

YassQweeennn · 08/11/2026 18:53

I don't know a single person that has stayed slim after coming off it. You're on it for life.

Yes that’s how it’s designed…

OddBoots · 10/11/2026 13:36

ThisLemonBee · 08/11/2026 18:20

Everyone, if you are using this medication and want to maintain the results (and long term health) if you’re not already you NEED to be resistance training. Muscle is more metabolically active than fat, the more you have the more you can eat (you will also
also be stronger and look better). If you’ve lost a lot of weight on the jabs and not been lifting weights you have likely lost a lot of muscle too and significantly reduced your metabolism. The app Ladder is brilliant for easy to follow programmes. Not a bad shout to get a few sessions with a coach if unsure on form. Good luck x

I heard the other day an interesting theory that it isn't the same body fat level the body tries to regain after loss, but instead it is the lean mass there is a pressure to replace - because fat is built so much easier than muscle and other lean tissue its increase is a side effect.

It would be interesting if it was even partly true as it would help explain why they have found that one of the most effective things someone can do to maintain a weight loss is exercise (even though exercise seems to only have a tiny benefit in weight loss) and might also explain why rebound weight seems to overshoot and people end up with even more fat than before they lost.

Hopefully the science will become clearer, especially as so many of us are taking these medications and are looking at what options we have going forward.

Wildfairy · 10/11/2026 13:38

Oxaloacetate · 09/11/2026 20:57

Yes that’s how it’s designed…

I mean you could argue that for all medications, it is not a cure, that if you take it it magically works when you stop taking it and you never encounter the issue again, No drugs do this.

Janeshelly · 10/11/2026 16:39

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Stuckoncrossroads · 10/11/2026 21:03

Similar experience op, I think keeping weight off after quitting jabs completely is unrealistic …I hope it gets cheaper and dose/ frequency can be decreased for maintenance…but I now believe it will be for life.
After finally reaching my perfect BMI, I tried going without and was okay for about a week, and then I was out of control and all I want to do is eat…I’ve gained 5 kg in 2 weeks and am horrified…. Mounjaro really affects my mental well being and I was hoping that somehow I will find a way to maintain my weight without it once I reach a healthy weight …tomorrow I’m taking my jab first thing in the morning:(

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