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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

June 2025 Starters - Mounjaro (thread 5)

1000 replies

Focusispower · 13/08/2025 20:19

Heading into month three now!

OP posts:
Thread gallery
32
MissMogs · 18/08/2025 07:25

I’m on the move again hurrah! Been stuck at 94/95 for a couple of weeks!

SW 104.4
CW 93.05
GW 65 ish

I would be thrilled to get into the 80s before September. No dress size changes yet, although clothes aren’t as tight as they were. I was kidding myself I was still the size I was wearing!

Only on week 2 of 7.5mg and suppression has been decent although mild nausea comes and goes and I’m a little constipated - unusual as pre MJ I had IBS! I have a 10mg pen in the fridge and have been trying to order a 12.5mg to last me a while before price rises, but now wondering if I’d be better staying at 7.5 or risk more nausea! I would much prefer to order as I need it according to how I felt and really really resent these price rises!

Gettingfitorbust · 18/08/2025 07:26

I did wonder if it was because I wasn’t eating enough, but I am having 3 decent meals and am only 5ft 2. It’s quite a psychological challenge isn’t it? Eat more to lose weight!

I’m using the app Nutracheck which calculated 1200 for me, and they are only light weights I’m using.

BoredReceptionist · 18/08/2025 07:38

Gettingfitorbust · 18/08/2025 07:26

I did wonder if it was because I wasn’t eating enough, but I am having 3 decent meals and am only 5ft 2. It’s quite a psychological challenge isn’t it? Eat more to lose weight!

I’m using the app Nutracheck which calculated 1200 for me, and they are only light weights I’m using.

I don’t know where you are, whether you’ve experienced this heat wave, but apparently that can cause water retention which would also look like no weight loss if that makes sense? Someone shared a post from Sally Gunnell explaining it, which made me feel better as I had no loss last week!

Gettingfitorbust · 18/08/2025 07:46

Thanks BoredReceptionist, that could be a factor maybe.
Love your Username btw!

BoredReceptionist · 18/08/2025 07:55

Gettingfitorbust · 18/08/2025 07:46

Thanks BoredReceptionist, that could be a factor maybe.
Love your Username btw!

I may be job hunting!!

SunandMoor · 18/08/2025 07:59

Hi checking in as I do enjoy reading these posts everyday!
wk 11 day 1 and I have lost 2.5lb this week which is great as last week I put a pound on for the first time! I have so far lost 1st 8lb so really happy (starting weight 15.2 now 13.8). I have made the brave decision to move from 5mg to 2.5mg as I did not feel 5mg gave me any more suppression that 2.5mg and I thought I could maybe get 6 weeks out of a 5mg pen to help with the price increase. Also I weirdly think it’s not a bad thing to have to use a bit of willpower! On my Shotsy app it shows the average loss and except for week 1 it’s 1.6lb a week and it was the same on 2.5mg as 5mg so that also supported my decision to move down. I think there is pressure to move up and I think I moved too quickly. I may regret this decision and do a half dose mid week but will let you know.

@Gettingfitorbust are you sure your portion sizes are 1200 calories. Might be worth weighing or really checking the sizes of portions? If so, then I am sure it will come off - trust in the process. In theory moving up should not make a difference if you are eating 1200 calories. I’d be tempted to do another week at 2.5mg.
good luck everyone.

ChiaraMontague · 18/08/2025 08:12

BMI just dipped under 30 for the first time in about 10 years! (It’s 29.8 but I’ll take it! 😂)

SW: 104.5kg
CW: 93.3kg
GW: 75kg

flameprincess · 18/08/2025 08:57

Has anyone tried split dosing and had any success? I'm in my second week of 5mg and I've noticed that the first 3 days after the jab the supression is insane to the point I struggle to get my calories in, but into day 4 it wanes and I am raging hungry again (though I am satiated very quickly upon eating). I'd rather have the hunger and enjoy my food but get full quick, than be off food completely but I can't drop down to 2.5mg again as that was becoming ineffective on my appetite as a whole.

I am wondering whether to inject 2.5mg on day 1 and another 2.5mg on day 4 and perhaps that will be a better balance for me rather than taking the 5mg in one hit...

Bloozie · 18/08/2025 10:13

W9D1 for me. Life has been madly chaotic over the last month, I’ve stopped recording everything I eat, my water intake has been patchy, some days I’ve only had one meal because I’ve been so busy, others I’ve eaten out and drunk too much alcohol… We’ve been having home renovations that have gone very very wrong and work has been horrific, then straight into my son and husband’s birthday week.

I went to take my injection yesterday and pen said no. Time had run away with me and I’d already done the 4th jab. No syringes to extract the golden dose. Luckily I buy from a local pharmacy so went this morning and he sold me two pens because of the price increase. I’m still on 2.5mg and feel it’s working well so I took one 2.5 and one 5. Pharmacist was happy to suggest that I split the doses on the 5 if I feel I don’t want to go up, as long as I store it in the fridge and am happy to go off license. I am.

I need to get my head back in the game. I don’t weigh myself so god knows what the last month has done. The cortisol must be suppressing weight loss. But my clothes are fitting better, people are commenting on the loss now, and I feel much stronger and fitter walking the dogs… Onwards and downwards.

Still lucky and seeing no side effects. Very reluctant to move up to 5 because of this. I have a month of 2.5 to decide though.

RJmama · 18/08/2025 10:14

I found you all again!

I’ve just finished my first week on 5mg. Side effects haven’t been too bad: a bit of nausea and some tiredness, especially 2-3 days after jab day.

And I’ve lost 4lbs! Finally dipped into the 12st range, after weeks stuck around 13st 1/2/3, so that feels good.

I’m down just over a stone overall as well.

RussianDoll76 · 18/08/2025 10:47

Gettingfitorbust · 17/08/2025 22:47

I don’t know what to do. I’m on week 9 and had slowly lost 11lbs, which I was OK with, but my weight loss has completely come to a halt over the last 2 weeks which is a pain.
I haven’t gone up from 2.5mg as I haven’t felt hungry except for just before meal times, and am managing OK just below 1200 daily calories.
Im walking 10,000 steps and lifting light weights. Is there any point in going for 5mg seeing as suppression seems Ok?

I have had a few weeks of stalling half a pound here or there . I am also 5ft 2 and I walk and always pottering about but that’s it exercise wise . The last week I have made sure I have eaten at least 1500 calories and had a little extra carbs as I was being uber healthy and all but cut them out and I have lost 3lbs . It’s hard to get your head around eating more to lose weight and I did struggle I forced myself to eat more but It has definitely worked ! I will definitely be continuing! Good luck op 😁

Wishiwasgardening · 18/08/2025 11:03

I'm coming up to the end of week 8, 21lbs lost, which is 10% of my starting weight!

I've had an extremely stressful few weeks with my Autistic 15 year old having a mental health crisis, then running away from home. Police, hospital, CAMHS, social services all involved etc. I'm convinced that without the MH I'd have resorted to comfort eating and drinking too much - but amazingly I've kept going. The weight loss did plateaux for a couple of weeks, but seems to be coming off again now.

Wishiwasgardening · 18/08/2025 11:12

flameprincess · 18/08/2025 08:57

Has anyone tried split dosing and had any success? I'm in my second week of 5mg and I've noticed that the first 3 days after the jab the supression is insane to the point I struggle to get my calories in, but into day 4 it wanes and I am raging hungry again (though I am satiated very quickly upon eating). I'd rather have the hunger and enjoy my food but get full quick, than be off food completely but I can't drop down to 2.5mg again as that was becoming ineffective on my appetite as a whole.

I am wondering whether to inject 2.5mg on day 1 and another 2.5mg on day 4 and perhaps that will be a better balance for me rather than taking the 5mg in one hit...

Yes, I've been spilt dosing from about week 2. I jab every 3 days to smooth out the peaks and it works really well for me. I always use insulin syringes rather than click counting so I can measure what I'm getting much more accurately. Plus I feel it's less likely to contaminate the pen when I'm hoing over the recommended 30 days. I'm using tiny 0.3ml insulin syringes to make the measurements easier. I'm currently taking 1.33mg every 3 days, which is 0.15ml from a 5mg pen. If I feel the suppression is waning I just increase by 0.05ml. I'm meticulous at calculating and recording, using dose diary and my own spreadsheet to be sure.

FoxRedPuppy · 18/08/2025 13:47

Just trying to catch up! I’m back from festival weekend with no phone signal. It was awesome.

I’ve jabbed, but not weighed (I only weigh in the morning, completely naked 😂)

I drank lots of beer and cider and the odd mojito over the weekend. And ate what I wanted (albeit smaller portions and no snacks). Loaded fries and a battered sausage as well as pizza!

Im on HRT (started with gel and now patches). I haven’t noticed weight gain and it certainly hasn’t stopped me losing. It’s far more likely to be from perimenopause/menopause.

Puffalicious · 18/08/2025 14:25

Hey all,

I'm in the 11s & that has buoyed me,👏 but after these weeks of plateau, only 1lb off. Perhaps I really am not eating enough. I also felt like the 2.5mg was, indeed, better for me so I might do another week of 3.75mg & then review down to 2.5mg- I'll see. I'm slower than many on here, but I'll just need to accept that.

I'll be 9 weeks tomorrow- does that make me week 9 or 10? 😃 I'm confused 😕.

SW 13st 3lbs
CW 11st 13lbs
GW 10st 10lbs (Healthy BMI).

BMI is 27.5 today, so I'm happy to be there.

Puffalicious · 18/08/2025 14:26

Wishiwasgardening · 18/08/2025 11:12

Yes, I've been spilt dosing from about week 2. I jab every 3 days to smooth out the peaks and it works really well for me. I always use insulin syringes rather than click counting so I can measure what I'm getting much more accurately. Plus I feel it's less likely to contaminate the pen when I'm hoing over the recommended 30 days. I'm using tiny 0.3ml insulin syringes to make the measurements easier. I'm currently taking 1.33mg every 3 days, which is 0.15ml from a 5mg pen. If I feel the suppression is waning I just increase by 0.05ml. I'm meticulous at calculating and recording, using dose diary and my own spreadsheet to be sure.

Edited

Great to hear this as I may dose 2.5mg with my next 5mg pen to lessen these cost rises.

HappyWineDay · 18/08/2025 15:30

Bloozie · 18/08/2025 10:13

W9D1 for me. Life has been madly chaotic over the last month, I’ve stopped recording everything I eat, my water intake has been patchy, some days I’ve only had one meal because I’ve been so busy, others I’ve eaten out and drunk too much alcohol… We’ve been having home renovations that have gone very very wrong and work has been horrific, then straight into my son and husband’s birthday week.

I went to take my injection yesterday and pen said no. Time had run away with me and I’d already done the 4th jab. No syringes to extract the golden dose. Luckily I buy from a local pharmacy so went this morning and he sold me two pens because of the price increase. I’m still on 2.5mg and feel it’s working well so I took one 2.5 and one 5. Pharmacist was happy to suggest that I split the doses on the 5 if I feel I don’t want to go up, as long as I store it in the fridge and am happy to go off license. I am.

I need to get my head back in the game. I don’t weigh myself so god knows what the last month has done. The cortisol must be suppressing weight loss. But my clothes are fitting better, people are commenting on the loss now, and I feel much stronger and fitter walking the dogs… Onwards and downwards.

Still lucky and seeing no side effects. Very reluctant to move up to 5 because of this. I have a month of 2.5 to decide though.

I think I would recommend that you do try to weigh yourself regularly. Without doing that, it's difficult for you to be able to assess how the previous month has actually gone. I always find that regardless of whether I "feel" hungry, if the effects are wearing off then I'm eating more and it's time to move up with the dose.
There is the option of counting clicks and moving to 3.75 rather than jumping to 5, if the weight loss has stalled - but as I say, if you don't measure, then it's hard to tell

Bloozie · 18/08/2025 15:53

HappyWineDay · 18/08/2025 15:30

I think I would recommend that you do try to weigh yourself regularly. Without doing that, it's difficult for you to be able to assess how the previous month has actually gone. I always find that regardless of whether I "feel" hungry, if the effects are wearing off then I'm eating more and it's time to move up with the dose.
There is the option of counting clicks and moving to 3.75 rather than jumping to 5, if the weight loss has stalled - but as I say, if you don't measure, then it's hard to tell

Yeah I do see this. But I have a tendency to fixate on the numbers if I know the numbers, and it becomes all-consuming. If I've had a 'bad' week, I find it insanely demotivating. And the scale of the journey ahead of me also becomes daunting. This is the first diet I've ever been on where I've just trusted the process rather than weigh myself obsessively, and I've found it much, much easier as a result. Clearly taking a drug that suppresses my appetite is a big part of this, but also not putting pressure on myself is making a huge difference.

I'm taking photos of myself, I have clothes I keep trying on, I can feel my knickers getting looser... Maybe when I am smaller I can pick up on weighing myself again.

I'm not at risk of eating more when I use my spreadsheet and record my calories. I aim for 1200 a day, don't beat myself up if I go to 1500. Not using the spreadsheet has been stupid these last few weeks. I haven't made terrible decisions - when I eat out I have steak or chicken and salad, not fries, if I have to get fast food it's a KFC rice bowl... There hasn't been a binge day, or even a day when I haven't chosen my food mindfully and picked the best of what's on offer. I just haven't kept control of it all.

I'll think on weighing myself. Not least because I'm currently just lying to my pharmacist and saying numbers. I have no idea how accurate they are, but he can see I'm obese, so...

HappyWineDay · 18/08/2025 16:33

@Bloozie I can completely understand your reasoning for not wanting to weigh, which is fair enough. I think your spreadsheet sounds a good idea as an alternative, in that it is keeping you mindful of what you are actually eating. Without using a tool like that I would personally find it so easy for bad habits to slip back in. Like you say, it allows you to keep control.
So if you feel you can get back to keeping that up to date, that sounds like a good plan. And if you are finding it difficult keeping the calories under control, then that's maybe the time to consider increasing your dose.

Focusispower · 18/08/2025 19:04

I don’t track now food or calories now @Bloozie but weighing has helped me to see impact even on weeks when I felt a bit grim and thought I hadn’t lost weight. If I feel like I’ve fallen off the wagon then I will go back to it, but I’m aiming for sustainable and not perfect, so I’ve had the odd drink, I have chocolate or an ice cream.

OP posts:
Sam187 · 18/08/2025 21:19

Hey all, W11D6 (jab night tonight and daily weigher). I had 0.18ml left in my 5mg pen, so golden dosed that with insulin needle and did 45 clicks of my new 5mg pen - just worked it out to be 5.5mg rather that 5 (oops)! Guess we'll see if the SEs kick in now 😂. Been on 3.75mg for around 6wks and starting to feel suppression wane, alongside a plateau, so hoping this gives a little boost.

We are getting a new fridge freezer at the weekend. Can someone please link me to the cool bag that keeps the pen cold? Just during the switch over, don't want to take any chances as I'm going over 30 days with my pen.

Loving all the losses this week! ❤️

Librariesrule · 19/08/2025 07:23

W9 D1
4lb off well happy. Having no loss last week focused the mind and I consciously made the effort to make sure I ate more and drank more water. Jab day today, have a good day everyone 😃

FoxRedPuppy · 19/08/2025 09:06

I actually can’t remember what week I am! 9 or 10! Anyway I’ve maintained this week, which given the amount of alcohol and chips I ate over the weekend, I’m happy with!

SunandMoor · 19/08/2025 09:55

Sam187 · 18/08/2025 21:19

Hey all, W11D6 (jab night tonight and daily weigher). I had 0.18ml left in my 5mg pen, so golden dosed that with insulin needle and did 45 clicks of my new 5mg pen - just worked it out to be 5.5mg rather that 5 (oops)! Guess we'll see if the SEs kick in now 😂. Been on 3.75mg for around 6wks and starting to feel suppression wane, alongside a plateau, so hoping this gives a little boost.

We are getting a new fridge freezer at the weekend. Can someone please link me to the cool bag that keeps the pen cold? Just during the switch over, don't want to take any chances as I'm going over 30 days with my pen.

Loving all the losses this week! ❤️

@Sam187 i use this one there are much more expensive options but this kept my pen cool on a trip to the US.
https://www.amazon.co.uk/dp/B0D474QQJ2?ref=ppx_yo2ov_dt_b_fed_asin_title&th=1

YOUSHARES Insulin Cooler Travel Case - Monjaro Travel Case with 2 Ice Packs, Keep Medicine Cool While Traveling for Diabetic Supplies (Blue) : Amazon.co.uk: Health & Personal Care

YOUSHARES Insulin Cooler Travel Case - Monjaro Travel Case with 2 Ice Packs, Keep Medicine Cool While Traveling for Diabetic Supplies (Blue) : Amazon.co.uk: Health & Personal Care

https://www.amazon.co.uk/dp/B0D474QQJ2?ref=ppx_yo2ov_dt_b_fed_asin_title&th=1&tag=mumsnet&ascsubtag=mnforum-weight-loss-injections-5391310-june-2025-starters-mounjaro-thread-5

neveroutofthekitchen · 19/08/2025 10:00

Sam187 · 18/08/2025 21:19

Hey all, W11D6 (jab night tonight and daily weigher). I had 0.18ml left in my 5mg pen, so golden dosed that with insulin needle and did 45 clicks of my new 5mg pen - just worked it out to be 5.5mg rather that 5 (oops)! Guess we'll see if the SEs kick in now 😂. Been on 3.75mg for around 6wks and starting to feel suppression wane, alongside a plateau, so hoping this gives a little boost.

We are getting a new fridge freezer at the weekend. Can someone please link me to the cool bag that keeps the pen cold? Just during the switch over, don't want to take any chances as I'm going over 30 days with my pen.

Loving all the losses this week! ❤️

If you have an insulated drinks bottle that will fit the pen, pop some ice (no water) in the bottom of the drinks bottle, wrap the pen in a sheet of kitchen towel and add the pen to the bottle. As the ice slowly melts and the kitchen towel absorbs the cold water, the pen will stay cool for up to 48 hours.

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