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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2025 Starters thread 4

963 replies

TheSpoonyNavyReader · 20/04/2025 19:22

New thread for all of us.

Thank you for allowing me to rant, share our ups and downs. Our group blows my mind of how we are so supportive of each other.

OP posts:
Thread gallery
25
Whereissummer24 · 22/04/2025 20:06

SpottyUnicorn · 22/04/2025 12:52

I had terrible SEs last week after my first 5mg and I was close to moving to 3.75 on Sunday, but I couldn’t get over the thought that it might be ok this time, so I ended up giving myself another 5mg injection. I was ready to feel as horrible as I did last week, I got Pepto Bismol ready, lots of mints (they seem to help with nausea) and a freezer full of ice (also for nausea), however… the expected SEs never came!
It has been over 50h since then and I am feeling absolutely fine!

I weighed myself yesterday and so far, I’ve lost 8lbs, which seems to be one of the smallest losses here. As it’s still a loss and more than I would have been able to lose without MJ, I am thrilled! I wonder if having PCOS is having any impact on the speed I’m losing weight. Anyone else with PCOS here?

I’ve lost about the same - am telling myself it’s a marathon not a sprint! Don’t have PCOS but I’m pretty sure years of very low carb did something horrendous to my body. Am thinking about booking for a private health check though just to check everything is in order.

FrozenFractal · 22/04/2025 21:11

NSV I don’t think I’ve read about before - my verrucas disappeared!!! I’ve had a cluster on my heel I’ve bee trying to get rid of actual years, tried everything and it only got worse. I can only assume that once I reduced sugar and processed food, all the inflammation disappeared and my immune system was finally able to fight the HPV.

GameOfJones · 22/04/2025 21:20

@FrozenFractal I was listening to a really interesting Zoe podcast today on inflammation and how it is linked to diet so it could well be that!

RuthEvershedforPM · 22/04/2025 21:58

Hello all - sounding pretty positive in our MJ village today! Happy days. NSV - managed a couple tuck jumps and burpees at the gym today! I normally just swap for squats and walk outs when it gets to that bit of the class but today was feeling game. I am not sure I’ll make a habit of it due to the high chance of wetting myself - but it’s also a sign of just a touch more confidence:)

Justformounjaro · 22/04/2025 23:04

TheBossOfMe · 22/04/2025 19:53

Yeas, good point. I'm lucky I haven't had many side effects so haven't had to buy much and had gym equipment (all the gear!). And am a total clothes hoarder - I'm wearing a skirt today that I bought over 25 years ago. I appreciate in the short term it's an expense for some. But over the longer term, it must pay off, surely? Not least in health benefits and the associated cost saving with those?

Of course, it’s an investment but I was being slightly facetious (after shelling out £30 on needles and doubling the meat bill) 😊 DP wonders why most meals involve chicken and the fridge is full of protein yoghurts. Ingo’s comment gave me a wry smile.

soupforbrains · 23/04/2025 02:09

I’m definitely saving money on food. I’ll grant you that the clothes coats I’m not factoring in but that’s because I’m refusing to buy any until I get to goal. I’ve spent about £70 on needle tips, supplements etc. but I’ve bought in bulk so those will last me at least 3 months, more for most of them. So that’s only £25/ month which frankly I was previously spending in a week on wine alone. Which I’m completely not now. So add in the food savings and I’m pretty certain it’s covering the costs of the injections.

popdepop · 23/04/2025 07:22

Morning, w5d5 and NSV, lost 5 inches from my waist. Next milestone is another loss of 2.5 pounds and I'll be 1.5 Stone down.
5mg supression has kicked in more, just feel sick and put off food. Have a great day all

GameOfJones · 23/04/2025 07:31

Morning all! Weekly weigh in and I've lost another 2lbs which I'm thrilled with.

SW: 14st
CW: 12st 9lbs
GW: 10st 7lbs

That makes 19lbs down in 7 weeks and 2st 6lbs down from where I was last summer.

Jab day today as well and I need to decide whether to stick to 3.75mg or go up to 5mg. I'm thinking that as it's a quiet week and I don't have much on this weekend it may be the time to try 5mg. But then again 3.75mg has been working really well for me. Decisions decisions.

Wouldratherbewatchingmafs · 23/04/2025 07:44

Hello everyone,

Hope you've all had a better last few days than me!! I'm starting to feel a bit better now but the last 36 hours have seen me have terrible diarrhoea. I've also been completely off my food :(
I think I will be taking a break from my injections until I feel completely better and then go back down to 2.5mg. My body clearly didn't like 5mg!! I've lost 5lbs this week but I'm not particularly happy as it's been at the expense of my health. However it has brought up my 6 STONE weight loss marker from last March.

My numbers below:
SW March 2024: 18 stone 10lbs
SW March 2025 (mounjaro): 14 stone 4.5lbs
CW: 12 stone 10lbs

Obviously a big part of me is very happy to see the back of those 6 stones and get to this point. However this week I hope I can gain 1lb or whatever as my body recuperates.

northernlight20 · 23/04/2025 08:00

Morning everyone. 3rd 5mg jab today, only had supression on the first week of 5mg jab. I’m ready to move up to 7.5mg. No loss this week.
sw 114.4kg
cw 107.3kg

Illbefinejustbloodyfine · 23/04/2025 09:06

@FrozenFractal that's interesting about the vertical, I've had a small one on the ball of my foot for ages. Still there currently (just checked...)

I am disappointed that my plantar fasciatis hasn't gone, lots of people have reported that there's went very quickly. Also, still snoring, nit as badly I don't think, but that could also be because I'm not drinking wine nightly

Oh well, can't have it all!

Illbefinejustbloodyfine · 23/04/2025 09:07

NSV - someone at work noticed I've lost weight. Also , I'm wearing a t shirt that was far too clingy before. It's the silky sort of jersey and was, well just tight really. Today, it's not!

akaFrosty · 23/04/2025 09:27

WK6 D1
2lbs loss this week so total loss 11.5lbs. Slower than others but I'm happy with that. It's more than I've been able to lose any other way. I took 3mg last week, but was starving by day 4.
I'll be cracking open my first 5mg this morning, but can't decide whether to do 3.75 or the full dose. I'm having dental work done tomorrow, so I'm worried about SEs.

@SmallSoupcon how are you feeling? Hope you're doing OK.

Illbefinejustbloodyfine · 23/04/2025 09:35

@soupforbrains I must be saving a fortune on wine! I've had 1 bottle a week for 5 weeks. I was getting through 5 - 7 bottles a week previously. Definitely problematic.

I've bought collagen powder but not much else really.

@akaFrosty I did the same, 3mg from the 5th dose, no loss atcall that week. then moved onto the 5mg pen. I did 3.75 on Sunday, and doing well on it so far I think. Definitely considering moving up to 5 for my next jab though. I'll see what happens at my weekly weigh in!

akaFrosty · 23/04/2025 09:38

Illbefinejustbloodyfine · 23/04/2025 09:35

@soupforbrains I must be saving a fortune on wine! I've had 1 bottle a week for 5 weeks. I was getting through 5 - 7 bottles a week previously. Definitely problematic.

I've bought collagen powder but not much else really.

@akaFrosty I did the same, 3mg from the 5th dose, no loss atcall that week. then moved onto the 5mg pen. I did 3.75 on Sunday, and doing well on it so far I think. Definitely considering moving up to 5 for my next jab though. I'll see what happens at my weekly weigh in!

Great, thanks for your thoughts. I don't want to be in the dentists chair with sulphur burps or diarrhea so I think I'll do 3.75.

SmallSoupcon · 23/04/2025 09:48

akaFrosty · 23/04/2025 09:27

WK6 D1
2lbs loss this week so total loss 11.5lbs. Slower than others but I'm happy with that. It's more than I've been able to lose any other way. I took 3mg last week, but was starving by day 4.
I'll be cracking open my first 5mg this morning, but can't decide whether to do 3.75 or the full dose. I'm having dental work done tomorrow, so I'm worried about SEs.

@SmallSoupcon how are you feeling? Hope you're doing OK.

Well done on your loss! I went up to 5mg on Monday. No noticeable improvement to my mood as yet, but I'm full of gas and air 😂
I've decided to try walking as therapy. I've been going out for 45 minute stomps, hoping for some kind of cumulative effect...

soupforbrains · 23/04/2025 09:49

@Illbefinejustbloodyfinewell exactly! My wine bill alone covers about 2/3 or the monthly costs of the injections and I’m definitely saving the rest with not buying convenience food and snacks on my commute/when I’m at work. Regardless of whether the ‘main’ food bill has come down. We also used to have takeaway 1-2 times a week and now just aren’t so thats a saving too.

The wine thing I find very interesting. As in general I just don’t even think of it. I’ve got a full wine rack in my kitchen and it’s just sitting there. Before MJ I would want (and have) a (large) glass of wine every night. And on stressful days polish off a bottle. But it just doesn’t even cross my mind. Nor does Gin which I also love.

I did drink quite a lot of wine last week but that was at the wake after dad’s funeral. Although I found the effects of MJ interesting. Some people have said that they had bad hangovers but I had none at all. What I DID notice was that I didn’t even get tipsy. Despite drinking a lot over a prolonged period. I think/assume that because MJ slows down absorption from the stomach my body was taking in the alcohol at a much slower rate. Slow enough in fact that my liver was metabolising it out of the system at roughly the same rate. I DID find though that that acidity of the wine sitting in my stomach was uncomfortable and gave me heartburn and made me just generally feel a bit ‘ick’.

today is not an official weigh day so hopefully things will work out for Saturday. But according to my scales this morning ive now lost 20% of my total targeted loss. In less than 2 months so that’s exciting. (Especially as I have such a lot to lose. 8st3lb total loss targeted)

GameOfJones · 23/04/2025 09:52

@Wouldratherbewatchingmafs sorry you've not been feeling well. But a 6 stone loss is absolutely incredible. Hope you feel better soon.

RuthEvershedforPM · 23/04/2025 09:59

Morning all

wk 7 day 1 today and the third lot of 5mg. Thrilled to have lost now 8.1kg which is a quarter of my target. Still don’t think I can see it really - argh!

feeling a little flat today - entering a busy work period, house is filthy and eldest back off to uni after a 10 days at home.

hoping to find some mojo!

TheBossOfMe · 23/04/2025 10:12

@Wouldratherbewatchingmafs Amazing weight loss. From everything I've been reading the advice is not to stop completely if you have bad SEs on a higher dose, but just to reduce back down to the lower dose that was OK for you. Maybe talk to your prescriber about what's best rather than completely stopping? 6 stone is incredible though!

@Illbefinejustbloodyfine Those NSVs are great, aren't they?

Yesterday was the first day that I really had to force myself to eat my calories, but managed it - lots of protein and veg, but also a lot of fruit. I'm super focused on making sure I eat a decent diet because I already have iron absorption issues and don't want to make those worse. So loading up on good nutrients, which is making me realise how many of my calories used to come from empty carbs (chopped mushrooms and lentils are my new best friends, eating them in place of white rice works really well for me) and TBH wine.

I gained all of my weight in a short space of time after an injury and subsequent operation - just carried on eating as if I was doing all the exercise I did before, and it piled on so fast, especially since I eat out a lot socially and for work. I think I went up two dress sizes in about 12 months, which is horrific. Almost all of which went straight to my belly. And then even when I was able to exercise again, the extra weight made it hard for me to actually do it properly. Try doing a burpee when your fat belly slams into the ground 😂

So NSV for me today was doing 10 burpees in a row, without any painful belly contact with the floor. I was dying doing them, felt a bit sick at the end and they weren't exactly great form wise. But I did them. Done badly is better than not done at all. I haven't been able to do that for 2 years now.

Oh, and I've shifted my post-Easter weight gain. Yay. Just moved the needle back to where I was before the weekend but that's fine.

SW 10st 4.6lb/144.6lb BMI 25.7 (prescribed MJ because of diabetes risk and hideous waist measurement)
CW 9st 3.9lb/129.9lb BMI 23 - 14.7lb down, 55.26% of target achieved. (Still overweight because of ethnicity but about to tip into healthy weight)
GW 8st 6lb/118lb (26.6lb total target loss, 11.9lb to go) BMI 20.9 (low BMI advised as target by doctor)

Loss by week:
W1 5.5lb
W2 1.3lb
W3 0.7lb (ate out loads)
W4 3.3lb
W5 0.5lb gain (ate out loads)
W6 4.4lb (Easter week plus period)
W7 so far no actual loss but shifted the 0.6lb gain over the long weekend

Jab day tomorrow but that's a week +1day from my last one, and the suppression is still there. Possibly 5mg is fine to continue on for now - I'll get my 7.5mg pen next week but might count clicks to continue at 5mg if I'm still tracking a weight loss and have enough suppression to continue the re-education of eating habits without feeling like I can't eat properly.

EchoNova · 23/04/2025 10:22

Morning everyone. Took my 3rd 5mg yesterday, thankfully no awful SE's which I was dreading, a little bit of nausea day after jab but that is it. Weighed myself this morning and I'm down 5lbs so I am thrilled however I had the flu last week so that has also contributed to the loss too as I was out of action for a few days.

@RuthEvershedforPM I'm the same in that I cannot see any difference either clothes still fit (mind I live in leggings and sweatshirts), the first time someone tells me I look like I've lost weight will hit like crack 😂

My story so far:

SW: 13st 7lbs
CW: 12st 2lbs
GW: 10st 5lbs

Week 1: -5lbs
Week 2: -3lbs
Week 3: -1lb
Week4: -4lb
Week 5: -1lb
Week 6: -5lbs
Total: 1st 5 lbs (19lbs)

I look to be following the same trend as when I have lost weight in the past with a two weekly weightloss cycle - small or no loss followed by a bigger loss the following week. If I stay on this path I'll be thrilled.

TheBossOfMe · 23/04/2025 11:20

Your pattern is really similar to mine, @EchoNova - small losses followed by a bigger drop rather than steady by week.

Things that are really working for me (and I've noticed the weeks where I've lost a lot have been the weeks when I've really stuck to these rules as much as possible):

Keeping to a 16:8 intermittent fasting pattern - which also works in terms of not eating too late and having my dinner mostly digested before I go to bed

Maximising sleep - definitely has an impact on my weight loss, no idea why. And being in bed by 11pm. Late nights seem to fuck with my eating habits the next day.

Eating round my plate, starting with protein, then vegetables and then complex carbs (mostly lentils and beans). Other carbs largely get left because I'm too full by then. I seem to not be able to eat things like bread, pasta rice and potatoes without slowing my weight loss a lot, so they need to be deprioritised!

Eating lots of fruit - I don't have much of a sweet tooth for puddings but have a bad habit of snacking on chocolate or ice cream in the evening at the weekends. I've replaced that with fruit, which I keep chopped up in the fridge (mostly orange segments, grapes and pomelo) so its nice and cold and easy to just grab.

At least 8 portions of fruit and veg a day, preferably 10. I know that sounds like a lot, but it's actually not that hard to do if you replace half the carbs on your plate with vegetables for both lunch and dinner, and snack on crudités and hummus if you need an in-between meal snack. Seems to help keep me regular as well!

One small portion of greek yoghurt a day after lunch (which is always protein plus salad, or protein plus a cup of vegetable soup), with nuts and seeds in it to increase protein intake.

Daily exercise even if it's just walking 5km after work. It doesn't have to be anything too strenuous to have an impact for me - if anything, I have to remind myself not to eat all my calories back after a run or weights session, whereas I don't feel the need to fuel after walking.

Logging everything on MFP - including weighing it all.

Writing this all down because there will be times when I'll stall and need to remind myself what works.

Amjam2025 · 23/04/2025 11:20

@TheBossOfMe I pushed my jab day back + 1 day to today aswel (i jabbed this morning) but also felt that suppression was still pretty good. That was my third 5mg jab. No awful side effects just nice suppression so i can still eat but don't get too tempted. I'll see how I get on this week and decide whether to move up or not. When i was on 2.5mg, the last two weeks were really hard and I had little to no suppression and winged it on willpower alone so got my fingers crossed that the 5mg is better.

I dressed in tight fitting clothes this morning and have had lots of lovely comments about looking slimmer which I'm absolutely over the moon with....makes me want to keep going and keep losing!! I'd encourage ppl to try wearing something more slim fit if you've not had comments yet (if you feel comfortable to) i think you'll be surprised at how many more ppl notice and will defo give you a mood lift!

I'm sorry I can't remember who wrote the comment about taller people finding that when they lose weight it doesn't show as much....yeah, I didn't think of that actually, I guess it's tough one way or another no matter what shape, size or height we are! Idnlove to know how much weight we've now lost between us all in this group. Absolutely love MJ and love this group:)

Illbefinejustbloodyfine · 23/04/2025 11:22

I'm having a strange time atm with food. Last night, I wanted to eat. I'd had 3 meals and a snack. Wasn't hungry, didn't need to eat, but really wanted the feeling of sitting down after the DC were in bed and snacking. Pre MJ this would be 1/2 to 1 bottle wine, maybe crisps or salted/chilli nuts. Biscuits, chocolate....

I went round in circles with it for a bit then had a tonic water and a handful of dried fruit/nut mix which did the trick. Absolutely didn't want chocolate.

Similar scenario just now, WFH today. Protein yogurt for breakfast. Ended up having a small slice apple. Again, not hungry but the urge to snack.

Wouldratherbewatchingmafs · 23/04/2025 11:36

TheBossOfMe · 23/04/2025 10:12

@Wouldratherbewatchingmafs Amazing weight loss. From everything I've been reading the advice is not to stop completely if you have bad SEs on a higher dose, but just to reduce back down to the lower dose that was OK for you. Maybe talk to your prescriber about what's best rather than completely stopping? 6 stone is incredible though!

@Illbefinejustbloodyfine Those NSVs are great, aren't they?

Yesterday was the first day that I really had to force myself to eat my calories, but managed it - lots of protein and veg, but also a lot of fruit. I'm super focused on making sure I eat a decent diet because I already have iron absorption issues and don't want to make those worse. So loading up on good nutrients, which is making me realise how many of my calories used to come from empty carbs (chopped mushrooms and lentils are my new best friends, eating them in place of white rice works really well for me) and TBH wine.

I gained all of my weight in a short space of time after an injury and subsequent operation - just carried on eating as if I was doing all the exercise I did before, and it piled on so fast, especially since I eat out a lot socially and for work. I think I went up two dress sizes in about 12 months, which is horrific. Almost all of which went straight to my belly. And then even when I was able to exercise again, the extra weight made it hard for me to actually do it properly. Try doing a burpee when your fat belly slams into the ground 😂

So NSV for me today was doing 10 burpees in a row, without any painful belly contact with the floor. I was dying doing them, felt a bit sick at the end and they weren't exactly great form wise. But I did them. Done badly is better than not done at all. I haven't been able to do that for 2 years now.

Oh, and I've shifted my post-Easter weight gain. Yay. Just moved the needle back to where I was before the weekend but that's fine.

SW 10st 4.6lb/144.6lb BMI 25.7 (prescribed MJ because of diabetes risk and hideous waist measurement)
CW 9st 3.9lb/129.9lb BMI 23 - 14.7lb down, 55.26% of target achieved. (Still overweight because of ethnicity but about to tip into healthy weight)
GW 8st 6lb/118lb (26.6lb total target loss, 11.9lb to go) BMI 20.9 (low BMI advised as target by doctor)

Loss by week:
W1 5.5lb
W2 1.3lb
W3 0.7lb (ate out loads)
W4 3.3lb
W5 0.5lb gain (ate out loads)
W6 4.4lb (Easter week plus period)
W7 so far no actual loss but shifted the 0.6lb gain over the long weekend

Jab day tomorrow but that's a week +1day from my last one, and the suppression is still there. Possibly 5mg is fine to continue on for now - I'll get my 7.5mg pen next week but might count clicks to continue at 5mg if I'm still tracking a weight loss and have enough suppression to continue the re-education of eating habits without feeling like I can't eat properly.

Edited

Thanks for your advice. Yes I will speak to the provider, good idea. I was thinking to push out my next jab by one or 2 days and go down to 3.75 or 2.5mg