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Weight loss injections/treatments

Discuss weight-loss injections and treatments, including personal experiences. Mumsnet hasn't checked the qualifications of anyone posting here. You may wish to speak to a medical professional before starting any treatments.

March 2025 Starters thread 4

963 replies

TheSpoonyNavyReader · 20/04/2025 19:22

New thread for all of us.

Thank you for allowing me to rant, share our ups and downs. Our group blows my mind of how we are so supportive of each other.

OP posts:
Thread gallery
25
28Spring · 22/04/2025 07:01

@Lolliz87 sorry to hear about your SE’s, just wondering what could help; are you taking any electrolytes as that might help with migraines? I started taking this one after a bit of research as it’s sugar free and got lots of other great supplements in like calcium which we need at the mo…

freesoul.com/products/free-soul-hydrate-electrolytes

Alao one thing I’ve not had whilst on MJ is constipation or burps, trying to think why that is and maybe it’s the full fat Greek yogurt with raspberries for fibre, think that keeps me regular…I have had diarrhoea when I’ve had high sugar foods or alcohol (not recommending you have those to counteract constipation though!!) Just saying I’m not SE free just still learning what works and what doesn’t…

A PP asked about collagen supplements a while back, I found a sugar free one with no nasties that’s tasteless, just mix a sooonful into my Greek yogurt everyday…

https://ancientandbrave.earth/products/true-collagen-powder

And another PP asked about syringes for golden dose…I can’t find the link someone posted previously but they were from MediSupplies, as they’re medical grade on there which is what you need, maybe someone else can post link xxx

My new mantra is “WEIGHTS+WATER+WALKING” which seems to be working, downwards trajectory on average, so steady away! Im not at a gym anymore (spending that money on MJ and supplements! 🤣) but I found this woman who does weights with just dumbbells for those of you who just need something simple you can do in 10 mins here and there..,it’s free on Insta or you can pay one payment and get unlimited access for £29
https://fitbusymum.uk/

And thanks everyone for all your posts. it’s so motivating to be part of this community xxx

Fitness Home

GET YOUR SEXINESS BACK in 30 DAYS!!! Even if you are very busy and don't have much time for yourself. Visit my challenges GET YOUR SEXINESS BACK in 30 DAYS!!! Even if you are very

https://fitbusymum.uk

Justformounjaro · 22/04/2025 07:09

CFCmum · 21/04/2025 23:28

They are just really itchy, spoke to a pharmacist who said as long as they local to the injection they are ok. Don’t want to stop taking it but they are getting a bit much. The itch wakes me up. I had some mosquito bites do the same I must just have sensitive skin but if anybody has any ideas please share. I have tried changing sites, letting the pen warm up, ice, Flonase, antihistamines, hydrocortisone, anthisane cream. Nothing worked so far

Poor you ☹️ That must be so frustrating.

The things you’ve mentioned are the ones I’ve seen recommended too. Is it linked to the dose you are taking or have you had it since day 1?

Whilst I know it’s not the same as a mosquito bite, one of the things I have tried with them is the hot teaspoon on the bite as soon as I’ve been bitten and that takes away the itch. I wonder if that might make it a little more bearable?

AintNobodyHereButUsChickens · 22/04/2025 07:42

CFCmum · 21/04/2025 23:28

They are just really itchy, spoke to a pharmacist who said as long as they local to the injection they are ok. Don’t want to stop taking it but they are getting a bit much. The itch wakes me up. I had some mosquito bites do the same I must just have sensitive skin but if anybody has any ideas please share. I have tried changing sites, letting the pen warm up, ice, Flonase, antihistamines, hydrocortisone, anthisane cream. Nothing worked so far

Oh how annoying for you! I really hope you can get it to calm down 🤞🏼

AintNobodyHereButUsChickens · 22/04/2025 07:44

What are we supposed to do with the used pens? Just throw them in the household rubbish or into the sharps bin?

CFCmum · 22/04/2025 07:50

@Justformounjaro 4weeks at 2.5 we’re fine then started happening on golden dose and every other dose only been doing 3.75. They started small but get bigger each time

saxonyv · 22/04/2025 07:53

Justformounjaro · 21/04/2025 09:28

Thanks for the new thread Spoony.

Start date on Mounjaro 1 March 2025

SW 15st 0lbs
CW 13st 13.7lbs

I’ve started to develop a reaction to my injection site ☹️ This is really annoying as DP is likely to notice this red mark on my stomach when I’ve not told him I’m using Mounjaro. I’m going to say it’s because my belt has rubbed in the wrong place because my trousers are falling down but that will only be believable for so long. I might have to start injecting in my thigh instead and blame mozzies biting me when gardening.

It started last week so I read about it. Took the pen out of the fridge early, used antihistamine cream afterwards but still came up as a red blotch and the one from last week hasn’t completely disappeared yet. It’s not hugely itchy which is something.

Edited

Do you wipe your stomach with the alcohol wipe?
I used to inject for a different condition and found wherever I wiped my skin with the wipe I’d have a reaction - it could’ve just been coincidence but might be worth omitting the wipe to see if it helps, maybe just wipe the area with a clean flannel and warm water before injecting instead.

SmallSoupcon · 22/04/2025 07:57

Morning all, weigh day today. No loss for me this week but it's no surprise as my suppression had been rubbish. Went up to 5mg yesterday so hopefully that'll switch things up.

SW 14st 3lbs
CW 13st 2lbs
GW 11st

saxonyv · 22/04/2025 08:06

Just caught up on all messages, can’t find specific ones to reply to but I echo what other posters have said about using electrolytes, I have some beroca type ones that you can pick up relatively cheap in the pharmacy.

Also someone mentioned about feeling flat and can attest to that! Feel like I’m going through the motions, although I was an emotional eater so maybe I’m not getting the same dopamine fix’s from food anymore so need to seek it from somewhere else 🤔

JudgingJudy · 22/04/2025 08:48

I use High 5 Zero. They come in a few flavours and help the water go down - which is a little struggle as I feel cold!

Weights +Water +Walking - I'm going to try this.

Did I read some people saying on the last thread, if they don't eat, the urge passes off? OMG is this magic? That has never happened to me. Is it a real thing?

@CFCmum that is worrying and sounds like you've tried everything. The tip of skipping the alcohol wipe is worth trying. I just inject post shower, I don't do anything to the local area and I've never had a problem. I'm an acupuncturist also and we don't clean the site before needling. The needle is pushing a micro amount of alcohol into the skin and maybe that is causing your reaction. You could also wait a few seconds to make sure all the alcohol was evaporated but I'd just skip.

TheBossOfMe · 22/04/2025 08:58

Another one recommending electrolytes as well - I used to get horrible post run headaches until I started taking them. I don't buy expensive "athlete" sachet ones, just cheap tablets that I drop in my bottle of water.

As predicted, after a somewhat overindulgent long weekend, I've gained a tiny bit, but looking back at how much I used to gain over Easter or Christmas, or a weekend away with friends, it's nothing close to the 3-4lb that I'd usually put on, only 0.6lb. Given I felt like I didn't really deny myself anything that I wanted to eat, and really hammered the chocolate, hot cross buns and wine, that feels like a result! I should be able to shift that again in no time, and continue the downward journey.

Annoyingly feel extremely full this morning though, not nauseous but I suspect I'll have to force lunch down, because I feel like I feel immediately after a very big meal, with a load of food sitting in my stomach. It's not a nice feeling at all, and I woke up really early because I felt so uncomfortable with it all sitting there. Zero problems going to the loo, so I'm not constipated or anything - it's just evidence of how much MJ slows your digestion down I guess. I'll have to keep reminding myself of how much I don't like this feeling whenever I'm tempted to eat more than I should - I definitely didn't need the hot cross bun bread and butter pudding last night!

Also feeling a tiny bit flat - but think that's more related to the fact that DD goes back to school today (she's a boarder because of the amount I travel overseas for work) and it'll be two weeks before I see her again because she's got loads on over the first two weeks back. Apart from the annoyance of my ex taking her on holiday over Mother's Day, it's felt like we've had a really lovely Easter holiday together and it's going to be very quiet indeed without her here.

@saxonyv I know what you mean about dopamine fix from food! I kind of still get it (still cooking really nice food, just keeping carbs down, protein up and packing my plate with veg) but it's not as much of a hit as it was. I'm trying to use exercise as the substitute, I definitely get a dopamine kick from that, especially as I'm starting to run a bit faster and lift heavier.

TheBossOfMe · 22/04/2025 09:02

@JudgingJudy The urge definitely passes, especially if you have a drink of water or something liquid whilst waiting for it to go. I think I've been guilty of confusing thirst with hunger in the past. So I get urges mid-morning, late afternoon and sometimes late evening - rather than having a snack (and I never snacked badly, but even fruit or nut calories eventually add up) I'll have a drink of some sort, and the urge to eat usually goes within about 10 mins.

TheSpoonyNavyReader · 22/04/2025 09:12

As you know I lost a disappointing 1LB last week.

I am a daily weigher got on the scales this morning and I am down 3lbs so I have hit 2 stone loss, if it stays like that until Friday.

OP posts:
TheBossOfMe · 22/04/2025 09:44

That's brilliant, @TheSpoonyNavyReader. Just goes to show how non-linear this journey is. I'm finding the losses come in fits and starts as well. My losses are a lot smaller, but still averaging 2.5ish lb per week, which is what I'd expected on my lower starting weight.

NHS BMI calculator still says I'm overweight though. Bloody Asian genes 😂

TheSpoonyNavyReader · 22/04/2025 09:50

TheBossOfMe · 22/04/2025 09:44

That's brilliant, @TheSpoonyNavyReader. Just goes to show how non-linear this journey is. I'm finding the losses come in fits and starts as well. My losses are a lot smaller, but still averaging 2.5ish lb per week, which is what I'd expected on my lower starting weight.

NHS BMI calculator still says I'm overweight though. Bloody Asian genes 😂

I was obese with a BMI of 31 at the start of March and now my BMI is 26.9 which blows my mind.

You are smashing it.

OP posts:
CFCmum · 22/04/2025 09:53

@JudgingJudy thanks I have tried not wiping with alcohol as well unfortunately they still appear 😢

soupforbrains · 22/04/2025 09:53

@TheSpoonyNavyReaderthats similar to me. I was sad to have ‘only’ maintained last week but I also weigh daily but only ‘log’ an official weight once a week. The day after my official weigh in I was down a lb and then down another one today so I’m feeling happier in the knowledge that it was just a momentary pause due to other factors rathe than the weight loss stalling.

I'm just about to order my next pen and I’m going to order a 5mg pen. I don’t plan to step all the way up to 5mg but I’m noticing the effects of the 2.5mg reducing so I’d like to gradually increase and 5mg pen will give me more flexibility around that. At the moment I am doing 2 x 1.25mg injections per week. Which would be 15 clicks on the 5mg pen. I plan to increase to 20clicks to start off with and only continue to increase in small increments as it fees necessary.

AddictedtoCrunchies · 22/04/2025 09:59

I'm in week 2 of 5mg and so far the awful SE of week 1 haven't appeared. Long may that last! I'm tired and have some on/off nausea like morning sickness but no stomach issues. I'm still not getting anywhere near the suppression I got in the first two weeks on 2.5mg though.

Weigh on #6 and down a stone. Happy with that but need to knuckle down now as only two weeks until my hot holiday.

TheSpoonyNavyReader · 22/04/2025 10:02

soupforbrains · 22/04/2025 09:53

@TheSpoonyNavyReaderthats similar to me. I was sad to have ‘only’ maintained last week but I also weigh daily but only ‘log’ an official weight once a week. The day after my official weigh in I was down a lb and then down another one today so I’m feeling happier in the knowledge that it was just a momentary pause due to other factors rathe than the weight loss stalling.

I'm just about to order my next pen and I’m going to order a 5mg pen. I don’t plan to step all the way up to 5mg but I’m noticing the effects of the 2.5mg reducing so I’d like to gradually increase and 5mg pen will give me more flexibility around that. At the moment I am doing 2 x 1.25mg injections per week. Which would be 15 clicks on the 5mg pen. I plan to increase to 20clicks to start off with and only continue to increase in small increments as it fees necessary.

I am going straight to 7.5 on Friday, as 5 has not done much for me, I have been lucky that my SE are feeling cold, constipation and dry lips.

I will let you all know what 7.5 is like and I can go down to 5 if I need to.

My son is Type 1 diabetic and we were chatting yesterday and he said that his medication has to be cold but once opened it can be stored at room temperature and used within 28 days. His diabetic consultant said that it will still work over 28 days and it is still ok for 3 months. My son is going travelling to Asia for his Honeymoon so will not have access to a fridge sometimes. The consultant said it’s the same for GLP1. This is what I am going to do for maintenance when I get there.

OP posts:
GiveMeWordGames · 22/04/2025 11:13

@TheBossOfMe @Amjam2025 the flip side of being taller (I'm 5ft 8) is that of course the weight coming off also doesn't look as obvious. 😁I also think what you describe is one of the reasons I've been able to kid myself, year on year, that I wasn't gaining THAT much weight and that I looked "ok", even as I crept up through clothes sizes.

24 hours after my first 5 mg and it's made me realise how much the appetite suppression had worn off on 2.5. Breakfast this morning was a small amount of greek yoghurt, apple and granola and that was pushing it. Two days ago I was happily having a couple of boiled eggs.

I've also dug out my weights. Bought years ago second hand in a well-meaning moment and then buried in assorted locations around the house as I barely used them. 🙄 Time to start making sure I don't lose too much muscle.....

GiveMeWordGames · 22/04/2025 11:14

TheSpoonyNavyReader · 22/04/2025 09:12

As you know I lost a disappointing 1LB last week.

I am a daily weigher got on the scales this morning and I am down 3lbs so I have hit 2 stone loss, if it stays like that until Friday.

Excellent news.

Lolliz87 · 22/04/2025 11:15

28Spring · 22/04/2025 07:01

@Lolliz87 sorry to hear about your SE’s, just wondering what could help; are you taking any electrolytes as that might help with migraines? I started taking this one after a bit of research as it’s sugar free and got lots of other great supplements in like calcium which we need at the mo…

freesoul.com/products/free-soul-hydrate-electrolytes

Alao one thing I’ve not had whilst on MJ is constipation or burps, trying to think why that is and maybe it’s the full fat Greek yogurt with raspberries for fibre, think that keeps me regular…I have had diarrhoea when I’ve had high sugar foods or alcohol (not recommending you have those to counteract constipation though!!) Just saying I’m not SE free just still learning what works and what doesn’t…

A PP asked about collagen supplements a while back, I found a sugar free one with no nasties that’s tasteless, just mix a sooonful into my Greek yogurt everyday…

https://ancientandbrave.earth/products/true-collagen-powder

And another PP asked about syringes for golden dose…I can’t find the link someone posted previously but they were from MediSupplies, as they’re medical grade on there which is what you need, maybe someone else can post link xxx

My new mantra is “WEIGHTS+WATER+WALKING” which seems to be working, downwards trajectory on average, so steady away! Im not at a gym anymore (spending that money on MJ and supplements! 🤣) but I found this woman who does weights with just dumbbells for those of you who just need something simple you can do in 10 mins here and there..,it’s free on Insta or you can pay one payment and get unlimited access for £29
https://fitbusymum.uk/

And thanks everyone for all your posts. it’s so motivating to be part of this community xxx

Thank you will give your suggestions a go. Jabbed last night and so far so good….havent woken with a headache/migraine like I have done after 5mg anyway so maybe this is the way forward! X

yikesanotherbooboo · 22/04/2025 11:47

Thankyou Spoony , signing in.

SpottyUnicorn · 22/04/2025 12:52

I had terrible SEs last week after my first 5mg and I was close to moving to 3.75 on Sunday, but I couldn’t get over the thought that it might be ok this time, so I ended up giving myself another 5mg injection. I was ready to feel as horrible as I did last week, I got Pepto Bismol ready, lots of mints (they seem to help with nausea) and a freezer full of ice (also for nausea), however… the expected SEs never came!
It has been over 50h since then and I am feeling absolutely fine!

I weighed myself yesterday and so far, I’ve lost 8lbs, which seems to be one of the smallest losses here. As it’s still a loss and more than I would have been able to lose without MJ, I am thrilled! I wonder if having PCOS is having any impact on the speed I’m losing weight. Anyone else with PCOS here?

TheBossOfMe · 22/04/2025 13:07

@SpottyUnicorn PCOS here as well, along with sluggish thyroid, poor iron/ferritin/B12. I think it's highly likely that with PCOS weight loss will be slower - I think 8lb is a good, healthy, sustainable loss.

FrozenFractal · 22/04/2025 13:09

Illbefinejustbloodyfine · 21/04/2025 20:08

What electrolytes are you using? I'm struggling with headaches a bit.

@Illbefinejustbloodyfine I tried these, after reading some good reviews about the ingredients. I find it easier to drink than just plain water and liked all the flavours.

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