Hi I'm totally new to this and I'm just wondering if anyone has a similar story or any effects of the depo injection I've recently came back from a holiday after getting the injection for the second time two months ago I have woke up with really bad anxiety worrying and panic attacks I have gone from being so happy to so depressed I have two little ones and thought it would be best to get some advice so I spoke to the doctor over the phone and they said it was very rare to become depressed or have anxiety from the depo injection I know nothing about it or why this is happening and would love to hear your stories 