well what are your needs?
Do you need to buy a house? If so how large?
Do you have a deposit?
Where are you considering moving to?
How old are your kids?
Will you be working (I ask because childcare will be one of your major expenses if you are working, especially if your kids are young).
As an eg, a 2 bed flat in my area of London will be about £3-400K, which with a 10% deposit would cost about £2000 in mortgage payments.
To rent it would be about £1500 per month.
Full time childcare will probably cost you between £700-£1500 per month per child, depending on their ages (the younger the child, the more expensive of course).
Council tax will be about £150 per month
Running a car will be about £50 per month in tax and insurance, plus whatever you use in fuel (say £100 a month for low mileage?).
Public transport will be about £80 per month for a zone 1-2 travel card (x 2 of course if both partners commute)
Utilities will be about £60 per month depending on usage.
Food will be about £400 a month plus depending on how extravagent you are!
I think you'd get a better idea if you supply a bit more info tbh?