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Estrogen patch

8 replies

positive1000vibes · 03/11/2026 15:41

Hi everyone. I am 47 and started HRT a week ago - I am on evorel 50 (still having periods so progesterone will start on 200mg in the middle of the cycle). I am pretty sure that the estrogen made my sleep more difficult (didn't sleep at all) and also made me more anxious. I am thinking of asking for a lower dose (25).

  1. Has anyone experienced insomnia and anxiety when they first started estrogen and did it settle down after a few weeks? and
2.anyone who has experience going for a lower dose and worked for them?
OP posts:
Autumnallaround · 03/11/2026 15:43

I slept bril

Autumnallaround · 03/11/2026 15:45

Sorry accidental post.

I slept brilliantly from the start. Oestrogen is my favourite hormone 😁 it's progesterone that made me anxious and unhappy.

However just checking you know that your progesterone is taken on the same day each month, irrespective of your cycle.

So choose a date and then take it on the same date each month.

pineapplebun82 · 03/11/2026 15:53

I’m not on estrogen yet, but have been taking progesterone for 10 days from day 15 of my cycle...so it depends..

positive1000vibes · 03/11/2026 15:55

Autumnallaround · 03/11/2026 15:45

Sorry accidental post.

I slept brilliantly from the start. Oestrogen is my favourite hormone 😁 it's progesterone that made me anxious and unhappy.

However just checking you know that your progesterone is taken on the same day each month, irrespective of your cycle.

So choose a date and then take it on the same date each month.

thanks. I thought you take it on day 15 of your existing cycle (though obviously my cycle is unpredictable). So are you saying you just start day 15-25 lets say and you stick to that every month?

OP posts:
positive1000vibes · 03/11/2026 15:56

pineapplebun82 · 03/11/2026 15:53

I’m not on estrogen yet, but have been taking progesterone for 10 days from day 15 of my cycle...so it depends..

how did it make you feel? I have read mixed reviews. I have taken high doses while pregnant but that was ages ago. Dr said to take it vaginally because of a condition I have.

OP posts:
Autumnallaround · 03/11/2026 16:01

positive1000vibes · 03/11/2026 15:55

thanks. I thought you take it on day 15 of your existing cycle (though obviously my cycle is unpredictable). So are you saying you just start day 15-25 lets say and you stick to that every month?

Yes exactly that.

You should never try and align it to a pre HRT cycle. This creates a cycle of it's own.

So I started HRT on the 6th January. I then added in progesterone on the 21st of January and every month after that.

pineapplebun82 · 03/11/2026 16:02

Hi, yes, been like that for couple of years now as my periods started coming really close together. I’m fine on it, not sure if I can tell the difference. Take it in the evening and sleep well on those days. Apparently, a period is supposed to come on few days after you stop taking it. I have had maybe 3/4 cycles when it didn’t…

JinglingSpringbells · 03/11/2026 16:25

It's a bit too soon to make a call on this @positive1000vibes .

Presumably you started HRT for symptoms and maybe those symptoms are just ramping up a bit regardless of HRT? It's easy to link the two, but it could be a coincidence. The medical advice is give a type and dose 3 months.

However, I do think that some GPs start women on too high a dose .

When I started (gel) my consultant - exceptionally well qualified and an expert in HRT/hormones - advised quarter a pump of gel and build up gradually.
That's half a 25mgs patch. I worked up to 2 pumps over several weeks.

So, you can only experiment. I wonder if gel might be a better option for you anyway?

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