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Sequential HRT and period has come early

11 replies

Adgitateddragonfly · 02/11/2026 07:56

I’m new to HRT - in peri and taking HRT mainly for the dreadful hormonal migraines.

This is month 2 and my period has arrived early, while there are still 5 progesterone tablets in the pack. I thought it was suppose to work a little like birth control, in that stopping the progesterone each month would trigger a period (that’s what happened last month).

Do I continue to take the rest of the progesterone or should I stop it and start it again on day 15 of this cycle? I’d love to be able to ask my doctor these questions, but by the time I get an answer it might be too late!

OP posts:
JinglingSpringbells · 02/11/2026 08:03

You stick to the regime. Finish the 5 tablets and then start the pack again ON THE SAME DATE EACH MONTH. Don't try to work it round your withdrawal bleed.

So whatever date you started this cycle (eg 16th October) start your next progesterone on 16h November.

Starting the bleed early is normal at first and your own cycle needs to be 'controlled' by HRT- that can take a few months.

Just one thing - you are supposed to take 2 capsules a day. So the pack has 30. Just wondering why you have 5 left? That suggests you have taken an odd number? How many days and how many tablets have you taken so far?

blueskyview · 02/11/2026 08:07

Yes mine always comes around day 10/11 of the progesterone but I carry on with the regime.

SquirrelStateOfMind · 02/11/2026 08:07

I think you keep taking it, your body's still adjusting. I'm on the sequi patches; month 1, period arrived early, in line with the pre HRT cycle; month 2, it waited still the end of the progesterone part, which meant no period at all that month! Now coming to the end of month 3, and it looks like it will happen in the progesterone break as it's supposed to.

Don't know if it's relevant to you, but I am getting mixed results in terms of symptoms. As none are serious, I am giving the current prescription a fair chance to settle before looking at review, and will see how things are after six months.

Adgitateddragonfly · 02/11/2026 08:09

Thank you! I’ll continue with the tablets then and hope it all sorts itself out.

I’ll check the box but I think it’s one capsule per day (the round white balls that are hard to swallow) for 15 days, and the oestrogen is the gel pump.

OP posts:
Autumnallaround · 02/11/2026 08:09

You take them all.

Pick a date each month and always start on the same date.

So I picked the 21st of the month and took them every month on that date. Irrespective of bleeding.

blueskyview · 02/11/2026 08:10

I take 2 per day.

uptowngal19 · 02/11/2026 08:11

I was also prescribed 1 per day
not 2. Also had less predicable bleeds since starting but I’m still in my first 6 months and adjusted from sequi patches to patches plus capsules after 3 so thinking it will take a while to settle.

JinglingSpringbells · 02/11/2026 08:15

Adgitateddragonfly · 02/11/2026 08:09

Thank you! I’ll continue with the tablets then and hope it all sorts itself out.

I’ll check the box but I think it’s one capsule per day (the round white balls that are hard to swallow) for 15 days, and the oestrogen is the gel pump.

It's 2 tablets a day, for 12 or 14 days, for sequential @Adgitateddragonfly

Looks as if you have misread the instructions?

JinglingSpringbells · 02/11/2026 08:18

Can we just clear this up?

OP says she is on sequential- that is a cycle.
The dose is 200 mgs (2 capsules) for either 12 or 14 days a cycle.
The choice of 12 days or 14 is partly down to how much you bleed- 14 days is more progesterone, but 12 days a month is adequate for endometrial protection.

The daily dose of 1 capsule is for women who are using combined continuous HRT in post menopause or late peri, who have very few natural periods, OR who have other symptoms whereby a daily dose is suggested.

Adgitateddragonfly · 02/11/2026 08:19

Oh crap it is 2 capsules! Thank you for pointing that out.

OP posts:
JinglingSpringbells · 02/11/2026 08:21

Adgitateddragonfly · 02/11/2026 08:19

Oh crap it is 2 capsules! Thank you for pointing that out.

Just carry on with 2 capsules a day till you get to your 14 days.
And whatever date you started the pack in October, start the next 14 days on the same DATE in November.

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