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Vaginal estrogen cream - side effects/over dose

4 replies

Tanfastic · 20/10/2026 19:49

I’ve been on this for a few years mainly to try and keep the pesky UTI’s at bay (I’m 53). It’s worked a treat so far even though I only use it once a week as I find it quite messy. I forgot a dose recently and so in my haste I decided to take a double applicator full (one applicator two days in a row). The next day my nipples were sore and I started getting the stretchy clear egg white discharge (tons of it) like I used to get when I ovulated. I’ve also got a painful vulva, like burning pain which seems to move around. I’ve been like this a week now. Has anybody else had anything like this after (over dosing 🙄) on it? I understood it shouldn’t have any systemic effects but this seems too much of a coincidence.

I don’t have a UTI as I’ve sent a dip to the lab in case it was that. I’ve also treated for thrush in case it was that. The timing seems too coincidental not to be the cream.

not had a period or ovulated for ten months (and to be honest since my periods stopped I’ve never felt better). I do have a gp appointment for something else on Friday so was going to mention if it doesn’t clear.

anyone had these issues?

OP posts:
MarcusBrigstockesfringe · 21/10/2026 15:14

Hi op. I use about three times the normal dose many times a week to help with scar tissue in my vulva.

I've never had any side effects. I don't find it messy either. Just shove it in at bedtime and change pants when I shower in the morning (obviously!)

MarcusBrigstockesfringe · 21/10/2026 15:15

Tbh that's a teeny tiny dose you are using, even if you double it up. I'm not sure how that would cause side effects. My private gynae tells me to use it daily and liberally. I use it like moisturiser.

JinglingSpringbells · 21/10/2026 15:17

More likely to be another period on the way. After 10 months you are not yet post menopause.
One application of vaginal estrogen is 100 times weaker than the strength of 1 day HRT on estrogen

Tanfastic · 21/10/2026 17:57

JinglingSpringbells · 21/10/2026 15:17

More likely to be another period on the way. After 10 months you are not yet post menopause.
One application of vaginal estrogen is 100 times weaker than the strength of 1 day HRT on estrogen

Oh great, I was hoping you wouldn’t say that 😤😂. Interestingly, when I consulted Dr Google it said it could cause these symptoms as some could enter the bloodstream so that’s why I was interested if it had happened to anybody else as I wasn’t sure it was correct.

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