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Really anxious about progesterone

3 replies

bestcatlife · 19/10/2026 18:46

Hi,
I’m 42 and have been experiencing symptoms for a couple of years. Explained all to my gp and have been prescribed 1 pump per day of oestrogen and 1 tablet of progesterone every day. I already take the progesterone only pill and assumed this would be ‘enough’ but gp said no, although research is being done apparently.
im really nervous because I suffer badly with depression and at the moment it is very bad due to - I think, a combination of life circumstances and perimenopause.
ive heard bad things about progesterone and I’m worried things will get worse with my MH…
has anyone had good experiences with it?

my main symptoms are increased anxiety, feeling of ‘overwhelm’ and awful brain fog (with dizziness/vertigo) I’m putting off starting it but I really do need to as these symptoms are awful. 😞

thanks

OP posts:
toiletpaperthief · 19/10/2026 18:51

I suffered from a hormone imbalance in my 30's and by OBGYN game me progesterone pills "to balance it out", I had to stop taking them after a week because it sky rocketed my anxiety and thought I was going mad, but a) I've always had GAD and 2) I'm super sensitive to hormones. I went back to my hormonally unbalanced self and felt soooo much better. Everyone is different and because it happened to me doesn't mean it will happen to you. I was not peri menopasal.

Jmess · 20/10/2026 13:12

@bestcatlife some of us are very intolerant to progesterones me one of them. I have tried numerous and different ways and they all make me feel crap do please don’t continue thinking you have to put up with it .
I’m butter y on Cyclogest vaginally once a month to create a bleed . Ask about digogesterone - Nalvee too it’s been re- released for use in hrt for this. Meant to be more tolerable but personally I don’t believe I’ll find something that really suits me.

I know a friend of a friend who ended up in a bad way trying to persevere with progesterone that gave her depression and suicidal thoughts , lost her relationship too.
its supposed to be the hormone that we need for calm etc but it did nothing like that for me !!

Seensta · 20/10/2026 13:42

It took me a while to find the right progesterone (I’m now on the bio identical one for 2 weeks out of 4) It took a few months to acclimatise but I now actually really look forward to the 2 weeks that I’m taking it! My anxiety is much better (it was previously quite debilitating) and I sleep so much better. I hadn’t actually thought about it until I read your post, but my brain fog is so much better these days too; it was pretty awful at one point.

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