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Menopause

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Family history of breast cancer and HRT - what to ask at my consultant appointment?

1 reply

ChazsBrilliantAttitude · 12/08/2026 13:46

I have a family history of breast cancer as DM had breast cancer close to the age of 40. I can’t remember exactly when as it’s over 50 years ago when I was a child. She died of another cancer at the age of 52 in the 1980s so no BRCA testing was done for her. I was screened for BC risk annually by the NHS from my mid 30s to early 50s (now covered by standard screening).
I also have a male sibling with prostate cancer.
I also suffered from endometriosis.
I’m 57 and I am tired, with brain fog and disrupted sleep.
I do use vaginal oestrogen as I know that is safe.

My GP has referred me to a consultant to discuss HRT risk. My appointment is next week any advice on what I should ask would be appreciated.

My thoughts were:

  1. Do I need BRCA testing?
  2. Are there options that are lower risk?
  3. Am I overthinking this?
  4. If I do take something will I need additional screening?

I want to get as much as I can out of the appointment.

I am realistic, I know there is a theoretical risk for everyone of taking HRT but for most it is outweighed by the benefits. I want enough information that I can do a proper risk benefit analysis for myself.

OP posts:
WhereAreWeNow · Today 22:26

I'm high risk (brca) and still take HRT.
What cancer did your mum die of and what other family history do you have? That will determine whether you can get a brca test on the NHS. It might be worth doing.
There are no special low risk options. Having said that, transdermal estrogen is lower risk than oral and micronised progesterone is lower risk than synthetic.
You won't get additional screening just because you're on HRT but you would if you did turn out to be higher risk due to a genetic mutation.
Good luck!

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