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Fatigue after starting HRT three weeks ago, has anyone else experienced this?

2 replies

Easter4us · 08/08/2026 20:19

I started HRT 3 weeks ago and am finding it very difficult to adjust. I’m very fatigued. I had a weeks holidays from work last week which I spent at home but still very tired this week. I am on Slynd every day and oestrogel 2 pumps. My job is stressful, as is home with teenagers and I am supporting my father in his 80s who lives alone. Just wondering has anyone experienced this level of fatigue after starting HRT. I didn’t realise how difficult it is to get on HRT!! Any similar experiences starting off on HRT

OP posts:
darlingpuss · 08/08/2026 21:50

Yes, same here, 53 and perimenopausal. First month on Slynd and 2 pumps of gel. Doctor hopes that this will reduce or stop the monthly heavy periods that I am finding so debilitating.

I have felt more tired than usual but 15 days in I’m starting to feel better in myself.

JinglingSpringbells · 09/08/2026 09:05

Why are you using Slynd? Is this doubling up as contraception?

It's not the usual form of progesterone - most women are offered micronised progesterone.

Progesterone affect mood and it might be worth considering changing to another type.

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