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Heavy bleeding after missed progesterone on HRT, has anyone experienced this?

9 replies

Cars4Gov · 15/07/2026 22:14

I've been on HRT for 6 months, all going well but I missed taking progesterone recently and experienced light bleeding which settled down after a few days...however bleeding has now restarted and much heavier. Quite a shock after such a long time of no periods.

From research it seems to be the balance isn't right. I will contact my GP but has anyone experienced this? Will I be able to continue HRT, and will the dose of Progesterone 100mg need to change?

OP posts:
Neurodiversitydoctor · 16/07/2026 06:31

You are bleeding because your uterine lining has been stimulated by the oestrogen and you are only 6 months out from your last period. Have you now taken your progesterone ?

Cars4Gov · 16/07/2026 07:18

I haven't had a period for 2 years, as I'm 55, been on HRT for 6 months. Missed progesterone but have now taken progesterone regularly for a few weeks, not missed any dose but have just experienced bleeding.

I'll contact my Dr as I know unexplained bleeding has to be investigated just disappointed as HRT seemed to be working and I was finally seeing the benefits.

OP posts:
SoScarletItWas · 16/07/2026 07:27

Sounds like you’re taking 100mg progesterone daily, ie continuous? How many days did you miss? Your current bleed could still be as a result of missing doses and your womb lining isn’t yet resettled.

I suspect all that will happen is your GP sends you for a scan to check all is well with your uterus.

It’s right that post meno bleeding needs to be investigated. I am not a dr but if it happened to me, I wouldn’t class this as ‘unexplained’ exactly, because I think stopping the progesterone is the explanation!

But do discuss with GP.

FanSpamTastic · 17/07/2026 01:31

I have had this - I missed around 3 days. It was a big shock! I went to the doctors and was referred for a scan - all was fine. Since then I’ve been v careful to take it regularly. Not had any recurrences, not had to change my dosage.

JinglingSpringbells · 17/07/2026 06:43

How many days or weeks did you miss?
Missing it for a day or two won't cause that much bleeding- maybe a bit of spotting. But if you missed it for weeks, that's different.

What dose of estrogen are you on?

Some women need to double the amount of progesterone to 200mgs a day to control the womb lining/

There is no reason from what you've said why you can't carry on with hrt but see your GP for a eview.

SnozPoz · 17/07/2026 06:53

Just get it checked out at your doctor's. If you were in perimenopause, bleeding when you missed your progesterone wouldn't be too strange, but if you haven't had a period in two years then you are officially in menopause and that's more worrying.

Divebar2021 · 17/07/2026 06:57

I had this when I misunderstood the dose of progesterone I was supposed to be taking and only took 1 tablet rather than 2. I was a little bit younger though (52) if that makes a difference.

Theolittle · 19/07/2026 03:42

im in Peri and still get light periods. Im also on mounjaro for 7weeks and haven’t had a period since starting. I’ve been on HRT for 4 years and now on 100mg plus oestrogen patches.

Ive just been away for a few days and missed progesterone. Yesterday I felt awful all day - very tired, very down, very heavy unexpected period in a very stressful situation. Got back to a social situation and I was struggling to cope so decided wine was a good idea to energise myself - and almost had a meltdown, completely lost it and didn’t feel myself at all for a few hours. I still can’t sleep my mind is weird!

I’ve had one other time I missed tablets and similar again - had a very stressful work situation that i couldn’t cope with then a horrible migraine a couple of days later

Hope you are ok. I wonder if some people are more sensitive to missed doses

Theolittle · 19/07/2026 04:04

Sorry have realised yours is a different situation - my brain really isn’t working well right now!

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