This is my third post this week HRT related so clear I am having an adjustment period!! - wondering if sometime may be able to offer some insight on this for me - I started HRT 19 days ago - 1 pump of oestrogel to start and 4 days ago I started on progesterone for days 15-26. I am also hypothyroid and on 87.5mg of thyroxine. The last few days I have been having hyperthyroid symptoms - since the progesterone it seems - anxious symptoms even though I don’t feel anxious about anything, increased heart rate, hot flashes, awful sleep unable to fall and stay asleep, nervous stomach feeling like I’m about to go into a job interview- all the same symptoms I had when I had sub acute thyroiditis and my TSH dropped to 0 - has anyone else experienced this with HRT? I feel wired but tired. I am thinking of stopping as it’s making me feel worse not better. I am 43 and it was a bit of an experiment due to a few peri symptoms but always hard to tell as they overlap often with thyroid problems. Thanks - any input/advice welcome!