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Evorel and anxiety

6 replies

Member988644 · 25/11/2025 20:07

Anyone have worse anxiety when on Evorel oestrogen only patches?
I went on a low dose 31/2 months ago to help with anxiety, but have felt much worse. I am on 25mcg and doc thought it might help me. The thought of upping the dose to 50 terrifies me as am so bad on 25mcg.

OP posts:
Shouldvegonewithalex · 25/11/2025 20:10

Yes. I came off it for that reason. I was OK for 2 weeks but had to take a progesterone tablet too - and it hit me like a train. I was a sobbing, irrational mess, it was awful. I stopped taking it after that. I know I need to go back to the docs ideally but my symptoms are pretty mild so I haven't made it a priority.

Speak to your GP, maybe a different treatment would be better for you - or an even lower dose.

SkibiddyRizz · 25/11/2025 20:15

My anxiety has increased and lm now wondering if it is connected

Member988644 · 25/11/2025 20:44

SkibiddyRizz · 25/11/2025 20:15

My anxiety has increased and lm now wondering if it is connected

I just don’t know what to do, go up, go down or come off altogether!

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Member988644 · 25/11/2025 20:45

Shouldvegonewithalex · 25/11/2025 20:10

Yes. I came off it for that reason. I was OK for 2 weeks but had to take a progesterone tablet too - and it hit me like a train. I was a sobbing, irrational mess, it was awful. I stopped taking it after that. I know I need to go back to the docs ideally but my symptoms are pretty mild so I haven't made it a priority.

Speak to your GP, maybe a different treatment would be better for you - or an even lower dose.

Thanks and yes I should speak to my GP

OP posts:
Frenchexs · 26/11/2025 21:35

Yes and no, it helped my constant background anxiety but at certain points during my cycle (seems to coincide with when my own estrogen would be spiking or raising) i get a very distinct wired but tired feeling but I’m giving it another month (1.5 months in) to see if it levels out. Have just reduced caffeine and that is helping.

Member988644 · 27/11/2025 06:14

Frenchexs · 26/11/2025 21:35

Yes and no, it helped my constant background anxiety but at certain points during my cycle (seems to coincide with when my own estrogen would be spiking or raising) i get a very distinct wired but tired feeling but I’m giving it another month (1.5 months in) to see if it levels out. Have just reduced caffeine and that is helping.

I have bitten the bullet and made an appointment with a menopause specialist for next week. I have also researched it and apparently having a dose of oestrogen that it too low can adversely affect the brain and cause anxiety, increasing the dose usually sorts this problem out. I had a hysterectomy in 2017 so have not had to take progesterone,
It will be interesting to hear what the doctor says about this, I will post again after I have seen her.

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