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Menopause

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HRT Micro-dosing in Peri

5 replies

Justsurfing · 04/11/2025 11:43

Hi ladies, does anyone have any experience of HRT micro-dosing? I am nearly 46 and starting to feel some mild peri symptoms. I don't feel these are bad enough to take the full HRT route just yet and have been looking at micro-dosing options, with the aim to keep a minimal, steady flow of hormones I've used chatgpt for ideas of a regime which I plan to discuss with my GP but would be interested to hear from anyone who has done this and your experience.
I used to take a low dose combined pill which i think kept my symptoms at bay however have recently had to stop due to it effecting my hair and causing vaginal dryness. These have improved slightly since stopping.
Thank you

OP posts:
Justputsomeyoghurtonit · 04/11/2025 19:52

How does one micro dose HRT? You are either on it, or not surely?

Do you mean take a low dose of oestrogen and therefore keep the progesterone to the minimum?

MrsArcher23 · 04/11/2025 19:58

The solution for vaginal dryness is a vaginal estrogen pessary. It will only get worse if you don’t treat it directly.

WellMaybeYouShouldntBeLivingHeeeeeeee · 04/11/2025 20:01

A DIY hormone regime created with advice from Chat GPT, eh? What could possibly go wrong

Chapattli · 04/11/2025 20:19

I'd be really interested to hear the responses although I'm aware itd be totally off label and I doubt anyone has ever been prescribed a lower than usual starting dose of Oestrogen.

I have tried going on HRT due to debilitating symptoms and got debilitating side effects which, as a full-time carer, I struggled to deal with.

I'd love to be able to try a very low dose and wonder just how little oestrogen you could take without progesterone. Sorry to all those that I make angry for discussing it.

JinglingSpringbells · 04/11/2025 20:33

@Justsurfing What do you consider a micro dose?

You can start with half a pump of gel. No reason not to. I did but it didn't control my symptoms. That's roughly the same as half a 25mcg patch.

You'd still have to use sequential progesterone of some sort for half the month. You can't get away with not using it.

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