I have been prescribed estrogen gel for peri symptoms. My NP has prescribed a low dose initially - one pump of 0.06% gel so 0.75 mg per day. My understanding was that if menstruating still (I am) you had to take progesterone too to reduce risk of endometrial cancer. I did ask the NP about this but she said at this low dose it's not necessary. But all the guidance including the drug leaflet says it is. Does anyone have experience of taking low dose estrogen gel without a progesterone?