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Menopause

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Progesterone intolerance, what worked for you?

51 replies

abouttoturn50 · 25/05/2024 19:02

I'm 49, I have tried HRT twice, the oestrogen part made me feel great but I'm having issues with the progesterone side. Firstly I tried Evorel Sequi which was great until the progesterone part which made me feel anxious and my mood was very low so I had the coil fitted and that was horrendous, the anxiety and dark thoughts were unbearable, I had it removed after only 2 weeks as I was going into a very dark place! I've gone through a cycle with no HRT, I'm 4 days before my period and I feel shit! Headaches, fuzzy head, fatigue and apathetic so I'm pretty sure I do need HRT! Should I have maybe tried longer on the Sequi? Just looking for suggestions before I speak to my GP really. Both times I was just told to stop rather than being given an alternative.

OP posts:
silverhamster · 26/05/2024 18:37

JinglingSpringbells · 26/05/2024 17:47

@silverhamster Tibolone is a type of HRT but it's synthetic (not body identical.) It does have an estrogenic effect on the body.

It doesn't require an additional progestogen with it because the compounds in it combine estrogen and progestogen.

I am not a medical professional, and don't fully understand it, but when I was on Tibolone a blood test showed I had zero detectable blood estrogen.

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