As above! I switched a week or so ago as I had noticed some increasing anxiety and my GP suggested Oestrogel. I'm a week in (2 pumps) and feel dreadful, achy, stiff, anxious. Can anyone relate/advise? Do you think it's worth persevering and for how long? I'm 61 and have been on Kliovance for 6 years with pretty good effect. Wishing I hadn't brought it up at my review