I'm 52 and on Evorel Sequi patches mainly for joint pain, but also helping with all the usual symptoms. The 50mg patch worked like magic for my joints for quite a few months. But the joint pain has come back, GP has added a 25mg patch to the mix to make 75mg. This has helped with brain fog, I feel much sharper, but still have joint pain. Would upping it to 100mg be too much? I've also not had a bleed for 2 cycles.