Have been on HRT for nearly three years. I'm 48. Evorel 50 patches, vagifem pessaries and Utrogestan tablets. All brilliant and sorted out my symptoms. I feel I'm struggling lately. I'm exhausted all the time, mood swings are common and no desire for sex at all. Work has been very busy and draining and there has been a lot going on with family and friends, so I don't know if it's just that or if I need dosage increasing. Anyone have any experience of this? Just made an appointment to chat with my doctor, but it won't be until the end of March! Thanks.